Ceramist (세라미스트)

The Korean Ceramic Society (한국세라믹학회)
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Mass spectrometry based on nanomaterials

나노물질을 이용한 질량분석 기술 개발동향

  • Park, Jong-Min (Materials Science and Engineering, Yonsei University) ;
  • Noh, Joo-Yoon (Materials Science and Engineering, Yonsei University) ;
  • Kim, Moon-Ju (Materials Science and Engineering, Yonsei University) ;
  • Pyun, Jae-Chul (Materials Science and Engineering, Yonsei University)
  • 박종민 (연세대학교 신소재공학과) ;
  • 노주윤 (연세대학교 신소재공학과) ;
  • 김문주 (연세대학교 신소재공학과) ;
  • 변재철 (연세대학교 신소재공학과)
  • Received : 2018.08.29
  • Accepted : 2018.09.19
  • Published : 2018.09.30
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Abstract

In conventional MALDI-TOF mass spectrometry, analyte molecules are known to be ionized by mixing with organic matrix molecules. As the organic matrix molecules are made into small fragments, they generate unreproducible mass peaks such that MALDI-TOF mass spectrometry is nearly impossible in the low mass-to-charge (m/z) range (< 1000). Additionally, the dried sample mixed with matrix were made as inhomogeneous crystal on metal plate. When the laser radiation was made on the sample crystal, the amount of generated sample ion was observed to be quite different according to the radiation point. Therefore, the quantitative analysis was very difficult even for the sample spots at the same concentration for the conventional MALDI-TOF mass spectrometry. In this work, we present laser desorption/ionization (LDI) mass spectrometry based on solid-matrices for the quantitative analysis of small molecules in the low m/z range by using MALDI-TOF mass spectrometry: (1) Carbon based nanostructures; (2) Semiconductor based nanomaterials; (3) Metal based nanostructures.

Keywords

References

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