Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Reference ranges for autonomic function tests in healthy korean adults

  • Park, Kee Hong (Department of Neurology, Gyeongsang National University Hospital) ;
  • Kim, Byoung Joon (Department of Neurology, Sungkyunkwan University School of Medicine) ;
  • Kang, Sa-Yoon (Department of Neurology, Jeju National University College of Medicine) ;
  • Oh, Sun-Young (Department of Neurology, Chonbuk National University School of Medicine) ;
  • Sohn, Eun Hee (Department of Neurology, Chungnam National University Hospital) ;
  • Song, Kyeong-jin (Department of Neurology, Chungnam National University Hospital) ;
  • Shin, Jin-Hong (Department of Neurology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine) ;
  • Kang, Kyoung Hwa (Department of Neurology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine) ;
  • Cho, Eun Bin (Department of Neurology, Gyeongsang National University Changwon Hospital) ;
  • Jeong, Heejeong (Department of Neurology, Gyeongsang National University Changwon Hospital) ;
  • Lee, Hyung (Department of Neurology, Keimyung University School of Medicine) ;
  • Kim, Hyun Ah (Department of Neurology, Keimyung University School of Medicine) ;
  • Kim, Rock Bum (Regional Cardiocerebrovascular Center, Gyeongsang National University Hospital) ;
  • Park, Ki-Jong (Department of Neurology, Gyeongsang National University Changwon Hospital)
  • Received : 2018.11.16
  • Accepted : 2018.12.07
  • Published : 2019.07.31
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Abstract

Background: The standardized autonomic function test has become widely available. However, there are no reference data for this test for the Korean population. This study explored reference data for sudomotor and cardiovagal function tests for the Korean population. Methods: The sweat volume by quantitative sudomotor axon reflex test, heart-rate response to deep breathing (HRdb), expiration:inspiration (E:I) ratio, and Valsalva ratio (VR) were measured in 297 healthy Korean volunteers aged from 20 to 69 years. Multivariate regression analysis was performed to evaluate the effects of age, sex, and body mass index on these variables. The 2.5th, 5th, 10th, 90th, 95th, and 97.5th percentile values were obtained for each investigation. Results: The sweat volume was higher in males than in females. The HRdb and E:I ratio were negatively correlated with age, and were higher in males than in females. The VR was negatively correlated with age, but it was not correlated with sex. Conclusions: This study has provided data on the reference ranges for sudomotor and cardiovagal function tests in healthy Korean adults.

Keywords

References

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