Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Uncommon coexistence of myasthenia gravis and amyotrophic lateral sclerosis

  • Cho, Eun Bin (Department of Neurology, Gyeongsang National University Changwon Hospital) ;
  • Yang, Tae-won (Department of Neurology, Gyeongsang National University Changwon Hospital) ;
  • Jeong, Heejeong (Department of Neurology, Gyeongsang National University Changwon Hospital) ;
  • Yoon, Changhyo (Department of Neurology, Gyeongsang National University Changwon Hospital) ;
  • Jung, Seunguk (Department of Neurology, Gyeongsang National University Changwon Hospital) ;
  • Park, Ki-Jong (Department of Neurology, Gyeongsang National University Changwon Hospital)
  • Received : 2019.06.07
  • Accepted : 2019.07.08
  • Published : 2019.07.31
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Abstract

Myasthenia gravis (MG) and amyotrophic lateral sclerosis (ALS) are distinct disorders. ALS affects motor neurons that control muscle movement, while MG controls communication between neurons and muscles, which occurs at neuromuscular junctions. However, on rare occasions, ALS develops after MG and vice versa. The coexistence of the two diseases represents a diagnostic challenge and requires thoughtful interpretation of clinical features. We present the case of a 53-year-old Korean male who developed ALS after MG, confirmed by clinical and electrophysiological follow-up.

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References

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