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Research Trends of Randomized Controlled Trials on Herbal Medicine Treatment for Atopic Dermatitis-Focusing on CNKI

아토피 피부염의 한약 치료에 대한 무작위대조군연구 중심의 연구 동향 - CNKI를 중심으로

  • Yang, Geum-Jin (Korean Medicine Dermatology Clinical Research Center, Wonkwang University) ;
  • Jo, Eun-hee (Department of Korean Medicine Acupuncture and Moxibustion, College of Korean Medicine, Wonkwang University) ;
  • Kang, Su-Jin (Korean Medicine Dermatology Clinical Research Center, Wonkwang University) ;
  • Hong, Jieun (Department of Korean Medicine Acupuncture and Moxibustion, College of Korean Medicine, Wonkwang University) ;
  • Shim, Yu-Hwa (Korean Medicine Dermatology Clinical Research Center, Wonkwang University) ;
  • Lee, Ju-Hyun (Department of Ophthalmology, Otolaryngology & Dermatology, College of Korean Medicine, Wonkwang University) ;
  • Park, Min-cheol (Korean Medicine Dermatology Clinical Research Center, Wonkwang University)
  • 양금진 (원광대학교 한방피부과학연구소) ;
  • 조은희 (원광대학교 한의과대학 침구과) ;
  • 강수진 (원광대학교 한방피부과학연구소) ;
  • 홍지은 (원광대학교 한의과대학 침구과) ;
  • 심유화 (원광대학교 한방피부과학연구소) ;
  • 이주현 (원광대학교 한의과대학 안이비인후피부과) ;
  • 박민철 (원광대학교 한방피부과학연구소)
  • Received : 2019.11.04
  • Accepted : 2020.04.20
  • Published : 2020.04.25

Abstract

The purpose of this study was to analyze the research trends of randomized controlled trials on herbal medicine treatment for atopic dermatitis in China for the last 5 years. We searched for randomized controlled trials with the intervention of herbal medicine for the treatment of atopic dermatitis in the CNKI (China National Knowledge Infrastructure) from January 2014 to December 2018. For the screening of the paper, we used '特应性皮炎' and '异位性皮炎' which mean atopic dermatitis and search was limited to three areas within Medicine & Public Health: Traditional Chinese Medicine, Traditional Chinese Medicinal Herbs, Combination of Traditional Chinese Medicine with Western Medicine. Among the 136 searched studies, we selected a total of 34 studies and analyzed a year of publication, subject characteristics, study design and intervention, prescribed herbal medicine and herbs, pattern identification, evaluation criteria, and outcomes. Longmu decoction (龍牡湯) and Polia Sclerotium (茯笭) was the most frequently prescribed medicine and herb. The most commonly used pattern identification was Blood deficiency and Wind-dryness (血虛風燥), and among them, the most frequently prescribed herb is Rehmanniae Radix (生地黃). In most studies using the total effectiveness and SCORAD index as an outcome measure, the herbal medicine treatment group showed statistically better results than the control group. As a result of the safety assessment, the herbal medicine treatment group was reported having significantly fewer side effects compared to the control group. Hence, it was confirmed that the intervention including herbal medicine had a significant effect on atopic dermatitis. This study would be able to provide the basis of clinical research on atopic dermatitis and applied to the treatment of atopic dermatitis.

Keywords

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