Applied Microscopy

  • Volume 50
  • /
  • Pages.20.1-20.9
  • /
  • 2020
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  • 2287-5123(pISSN)
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  • 2287-4445(eISSN)
Korean Society of Microscopy (한국현미경학회)
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Fine structure of the intercalated disc and cardiac junctions in the black widow spider Latrodectus mactans

  • Yan Sun (Department of Biological Sciences, Dankook University) ;
  • Seung-Min Lee (Department of Biological Sciences, Dankook University) ;
  • Bon-Jin Ku (Department of Biological Sciences, Dankook University) ;
  • Myung-Jin Moon (Department of Biological Sciences, Dankook University)
  • Received : 2020.08.07
  • Accepted : 2020.09.15
  • Published : 2020.12.31
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Abstract

Arthropods have an open circulatory system with a simple tubular heart, so it has been estimated that the contractile pumping structure of the cardiac muscle will be less efficient than that of vertebrates. Nevertheless, certain arthropods are known to have far superior properties and characteristics than vertebrates, so we investigated the fine structural features of intercalated discs and cardiac junctions of cardiac muscle cells in the black widow spider Latrodectus mactans. Characteristically, the spider cardiac muscle has typical striated features and represents a functional syncytium that supports multiple connections to adjacent cells by intercalated discs. Histologically, the boundary lamina of each sarcolemma connects to the basement membrane to form an elastic sheath, and the extracellular matrix allows the cells to be anchored to other tissues. Since the intercalated disc is also part of sarcolemma, it contains gap junctions for depolarization and desmosomes that keep the fibers together during cardiac muscle contraction. Furthermore, fascia adherens and macula adherens (desmosomes) were also identified as cell junctions in both sarcolemma and intercalated discs. To enable the coordinated heartbeat of the cardiac muscle, the muscle fibers have neuronal innervations by multiple axons from the motor ganglion.

Keywords

Acknowledgement

This work was partly supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (NRF-2019R1I1A3A01062105).

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