Applied Chemistry for Engineering (공업화학)

The Korean Society of Industrial and Engineering Chemistry (한국공업화학회)
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One-pot Synthesis of Multifunctional Mn3O4/mesoporous Silica Core/shell Nanoparticles for Biomedical Applications

  • Lee, Dong Jun (School of Chemical and Biological Engineering, Seoul National University) ;
  • Lee, Nohyun (School of Advanced Materials Engineering, Kookmin University) ;
  • Lee, Ji Eun (School of Chemical Engineering, Chonnam National University)
  • Received : 2021.12.23
  • Accepted : 2022.01.07
  • Published : 2022.02.10
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Abstract

Multifunctional nanomaterials based on mesoporous silica nanoparticles (MSN) and metal oxide nanocrystals are among the most promising materials for theragnosis because of their ease of modification and high biocompatibility. However, the preparation of multifunctional nanoparticles requires time-consuming multistep processes. Herein, we report a simple one-pot synthesis of multifunctional Mn3O4/mesoporous silica core/shell nanoparticles (Mn3O4@mSiO2) involving the temporal separation of core formation and shell growth. This simple procedure greatly reduces the time and effort required to prepare multifunctional nanoparticles. Despite the simplicity of the process, the properties of nanoparticles are not markedly different from those of core/shell nanoparticles synthesized by a previously reported multistep process. The Mn3O4@mSiO2 nanoparticles are biocompatible and have potential for use in optical imaging and magnetic resonance imaging.

Keywords

Acknowledgement

This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2021R1A2C1011317) and Chonnam National University (Grant number : 2021-2505).

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