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Bony Union of Osteochondral Lesion of the Talus after Bone Marrow Aspirate Concentrate and Matrix-Induced Chondrogenesis: A Case Report

골수흡인물 농축액 및 기질유래연골형성 수술 이후 관찰된 거골의 골연골병변의 골유합: 증례 보고

  • Tae Hun Song (Department of Orthopaedic Surgery, Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Jin Soo Suh (Department of Orthopaedic Surgery, Ilsan Paik Hospital, Inje University College of Medicine) ;
  • Jun Young Choi (Department of Orthopaedic Surgery, Ilsan Paik Hospital, Inje University College of Medicine)
  • 송태훈 (인제대학교 의과대학 일산백병원 정형외과학교실) ;
  • 서진수 (인제대학교 의과대학 일산백병원 정형외과학교실) ;
  • 최준영 (인제대학교 의과대학 일산백병원 정형외과학교실)
  • Received : 2023.10.06
  • Accepted : 2023.10.28
  • Published : 2023.12.15

Abstract

Traditionally, arthroscopic microfracture and autologous osteochondral autograft transplantation have been the primary surgical treatments for osteochondral lesions of the talus. On the other hand, recent advancements have introduced alternative approaches, such as autologous chondrocyte transplantation, matrix-derived autologous chondrocyte transplantation, intra-articular injection of concentrated bone marrow aspirate concentrate, and the use of fibrin glue to address chondral defects. Furthermore, some studies have explored a combination of bone marrow aspirate and matrix-derived chondrogenesis. In light of these developments, this report presents a case study of a young male patient in his early twenties with a relatively large osteochondral lesion exceeding 1.5 cm2 on the medial talar dome. Instead of removing the osteochondral lesion, a surgical approach was employed to retain the lesion while addressing the unstable cartilage in the affected area. This approach involved a combination of bone marrow aspirate concentrate and matrix-derived chondrogenesis. The treatment yielded favorable clinical outcomes and ultimately successfully induced the bony union of osteochondral lesions. This paper reports the author's experience with this innovative approach with a review of the relevant literature.

Keywords

References

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