Annals of Clinical Neurophysiology

  • 제25권2호
  • /
  • Pages.78-83
  • /
  • 2023
  • /
  • 2508-691X(pISSN)
  • /
  • 2508-6960(eISSN)
대한임상신경생리학회 (The Korean Society of Clinical Neurophysiology)
권호 표지
DOI QR코드

DOI QR Code

Nociplastic pain

  • Jeong Hee Cho (Department of Neurology, National Health Insurance Service Ilsan Hospital)
  • 투고 : 2023.08.05
  • 심사 : 2023.09.27
  • 발행 : 2023.10.30
PDF 다운로드
⟨ 이전 논문 다음 논문 ⟩

초록

Nociplastic pain refers to pain arising from altered nociception without evidence of tissue or somatosensory damage. It encompasses various clinical conditions with shared neurophysiological mechanisms involving different organ systems. Nociplastic pain can occur independently or alongside chronic pain conditions with a nociceptive or neuropathic origin. This review introduces the concept of nociplastic pain, its clinical manifestations and the underlying pathophysiology. Taking a biopsychosocial approach can lead to a better understanding of nociplastic pain and improved treatment outcomes for affected individuals.

키워드

참고문헌

  1. Raja SN, Carr DB, Cohen M, Finnerup NB, Flor H, Gibson S, et al. The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises. Pain 2020;161:1976-1982. https://doi.org/10.1097/j.pain.0000000000001939
  2. International Association for the Study of Pain. IASP terminology [Internet]. Washington (DC): International Association for the Study of Pain; c2023 [accessed 2023 Aug 3]. Available from: https://www.iasp-pain.org/resources/terminology/.
  3. Cohen SP, Vase L, Hooten WM. Chronic pain: an update on burden, best practices, and new advances. Lancet 2021;397:2082- 2097. https://doi.org/10.1016/S0140-6736(21)00393-7
  4. Murphy AE, Minhas D, Clauw DJ, Lee YC. Identifying and managing nociplastic pain in individuals with rheumatic diseases: a narrative review. Arthritis Care Res (Hoboken) 2023;75:2215-2222. https://doi.org/10.1002/acr.25104
  5. Kosek E, Cohen M, Baron R, Gebhart GF, Mico JA, Rice ASC, et al. Do we need a third mechanistic descriptor for chronic pain states? Pain 2016;157:1382-1386. https://doi.org/10.1097/j.pain.0000000000000507
  6. World Health Organization. ICD-11 for mortality and morbidity statistics [Internet]. Geneva: World Health Organization; c2023 [accessed 2023 Aug 3]. Available from: https://icd.who.int/browse11/l-m/en#/http://id.who.int/icd/entity/1326332835.
  7. Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, et al. Chronic pain as a symptom or a disease: the IASP classification of chronic pain for the International Classification of Diseases (ICD-11). Pain 2019;160:19-27. https://doi.org/10.1097/j.pain.0000000000001384
  8. Fitzcharles MA, Cohen SP, Clauw DJ, Littlejohn G, Usui C, Hauser W. Nociplastic pain: towards an understanding of prevalent pain conditions. Lancet 2021;397:2098-2110. https://doi.org/10.1016/S0140-6736(21)00392-5
  9. Nicholas M, Vlaeyen JWS, Rief W, Barke A, Aziz Q, Benoliel R, et al. The IASP classification of chronic pain for ICD-11: chronic primary pain. Pain 2019;160:28-37. https://doi.org/10.1097/j.pain.0000000000001390
  10. Kosek E, Clauw D, Nijs J, Baron R, Gilron I, Harris RE, et al. Chronic nociplastic pain affecting the musculoskeletal system: clinical criteria and grading system. Pain 2021;162:2629-2634. https://doi.org/10.1097/j.pain.0000000000002324
  11. Nijs J, Lahousse A, Kapreli E, Bilika P, Saracoglu I, Malfliet A, et al. Nociplastic pain criteria or recognition of central sensitization? Pain phenotyping in the past, present and future. J Clin Med 2021;10:3203.
  12. den Boer C, Dries L, Terluin B, van der Wouden JC, Blankenstein AH, van Wilgen CP, et al. Central sensitization in chronic pain and medically unexplained symptom research: a systematic review of definitions, operationalizations and measurement instruments. J Psychosom Res 2019;117:32-40. https://doi.org/10.1016/j.jpsychores.2018.12.010
  13. Nijs J, George SZ, Clauw DJ, Fernandez-de-las-Penas C, Kosek E, Ickmans K, et al. Central sensitisation in chronic pain conditions: latest discoveries and their potential for precision medicine. Lancet Rheumatol 2021;3:e383-e392. https://doi.org/10.1016/S2665-9913(21)00032-1
  14. Ramaswamy S, Wodehouse T. Conditioned pain modulation-A comprehensive review. Neurophysiol Clin 2021;51:197-208. https://doi.org/10.1016/j.neucli.2020.11.002
  15. Ibancos-Losada MDR, Osuna-Perez MC, Castellote-Caballero MY, Diaz-Fernandez A. Conditioned pain modulation effectiveness: an experimental study comparing test paradigms and analyzing potential predictors in a healthy population. Brain Sci 2020;10:599.
  16. Neblett R. The central sensitization inventory: a user's manual. J Appl Biobehav Res 2018;23:e12123.