Animal Bioscience

Asian Australasian Association of Animal Production Societies (아세아태평양축산학회)
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Evaluation of genetic differentiation and search for candidate genes for reproductive traits in pigs

  • Elena Romanets (Faculty of Biotechnology, Don State Agrarian University) ;
  • Siroj Bakoev (Faculty of Biotechnology, Don State Agrarian University) ;
  • Timofey Romanets (Faculty of Biotechnology, Don State Agrarian University) ;
  • Maria Kolosova (Faculty of Biotechnology, Don State Agrarian University) ;
  • Anatoly Kolosov (Faculty of Biotechnology, Don State Agrarian University) ;
  • Faridun Bakoev (Faculty of Biotechnology, Don State Agrarian University) ;
  • Olga Tretiakova (Faculty of Biotechnology, Don State Agrarian University) ;
  • Alexander Usatov (Academy of Biology and Biotechnology named after. DI. Ivanovsky, Southern Federal University) ;
  • Lyubov Getmantseva (Faculty of Biotechnology, Don State Agrarian University)
  • Received : 2023.08.11
  • Accepted : 2023.11.22
  • Published : 2024.05.01
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Abstract

Objective: The use of molecular genetic methods in pig breeding can significantly increase the efficiency of breeding and breeding work. We applied the Fst (fixsacion index) method, the main focus of the work was on the search for common options related to the number of born piglets and the weight of born piglets, since today the urgent task is to prevent a decrease in the weight of piglets at birth while maintaining high fertility of sows. Methods: One approach is to scan the genome, followed by an assessment of Fst and identification of selectively selected regions. We chose Large White sows (n = 237) with the same conditions of keeping and feeding. The data were collected from the sows across three farrowing. For genotyping, we used GeneSeek GGP Porcine HD Genomic Profiler v1, which included 68,516 single nucleotide polymorphisms evenly distributed with an average spacing of 25 kb (Illumina Inc, San Diego, CA, USA). Results: Based on the results of the Fst analysis, 724 variants representing selection signals for the signs BALWT, BALWT1, NBA, and TNB (weight of piglets born alive, average weight of the 1st piglets born alive, total number born alive, total number born). At the same time, 18 common variants have been identified that are potential markers for both the number of piglets at birth and the weight of piglets at birth, which is extremely important for breeding work to improve reproductive characteristics in sows. Conclusion: Our work resulted in identification of variants associated with the reproductive characteristics of pigs. Moreover, we identified, variants which are potential markers for both the number of piglets at birth and the weight of piglets at birth, which is extremely important for breeding work to improve reproductive performance in sows.

Keywords

Acknowledgement

This work was supported by the Russian Science Foundation grant no. 22-76-10015.

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