Advances in nano research

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Nanostructured surfaces and disinfectants: A new frontier in environmental hygiene monitoring and surgical infection prevention

  • Jia Fang (Chun'an First People's Hospital Infection Control Department) ;
  • Meiyun Wu (Department of Rheumatology, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University)
  • Received : 2025.09.15
  • Accepted : 2026.02.19
  • Published : 2026.02.25
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Abstract

Healthcare-associated infections and, in particular, the surgical site infections (SSIs) are acute problems regardless of the enhancements in the antiseptic agents, sterilization procedures, and the observation of the environment. The primary techniques of the conventional approach to disinfection are the application of chemical agents, the effectiveness of which can be negatively determined by improper use, microorganism resistance, and the rapid recontamination of the surface. One of the newer methods that have been implemented in recent years with promising results is nanostructured surfaces to supplement environmental hygiene as well as reduce the number of microbes in clinical settings. The antimicrobial properties of the nanoscale-engineered surfaces are inherent to the physical action principles that comprise the membrane disruption, reduced microbial adhesion, and biofilm prevention in most of the cases that do not require chemical biocides. Nanostructured materials may also be implemented synergistically with legacy disinfectants to offer superior disinfectants, longer antimicrobial and greater reliable hygienic monitoring. The paper shall discuss the relevance of nanostructured surfaces in environmental hygiene monitoring and how this could be relevant in SSI prevention. We take into consideration the modern trends in nanofabrication processes, processes of antimicrobial protection as well as the compatibility with existing disinfectants, and new methods of determining the surface and microbial survival condition. The other problem of interest is the problem of durability, cost, safety and regulatory issues. The concept of nanostructured surfaces can be regarded as a novel development in the healthcare hygiene practices, based on an integration of materials science and infection prevention and environmental monitoring. They are able to contribute to the existence of stronger infection control measures, reduced reliance on chemical disinfectants, and improved patient outcomes in the surgical and high-risk clinical environments.

Keywords

References

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