• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.3
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• pp.479-482
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• 2002

Jookrhyuk (Bambusae Caulis in Liqamen) is one of the most important ingredients for treating Diabetes mellitus. Various aspects of quality of Jookrhyuk produced in Korea depending on carbonization process were compared. The pH Value was the highest in Jinyoungsangsa Jookrhyuk(pH 3.17) among the three different Jookrhyuk samples. Damyangsan Jookrhyuk that contains high level of total sugars(8.0 Brix, %) show incresed level of tar contents, it exhibited positive realationship between total sugar and tar contents. Concentration of methanol and phenolic compounds which are related to toxicity were the highest in Damyangsan Jookrhyuk(1.34㎎/㎖, 3.84㎎/㎖ respectively). The harmful heavy elements were not found in the evaluated Jookrhyuk samples. In coclusion, it was suggested that Bambusae Caulis in Liqamen should be further puryfied for using as main oral medicines for treating Diabetes mellitus.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.1
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• pp.151-156
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• 2003

This study was carried out to investigate the optimal mixed extract with Bambusae Caulis in Liquamen in order to strengthen anti-diabetic effects on the hyperglycemia induced by streptozotocin in mice. The original Bambusae Caulis in Liquamen filtered and refined. The effects of Bambusae Caulis in Liquamen and Mixed extracts(Bamboo Juice) with Bambusae Caulis in Liquamen were administered to mice for 4weeks and its anti-diabetic effect examined. Mice used in this experiment were divided into three groups and saline(control), Bamboo Juice mixed with refined Bambusae Caulis in Liquamen(BJ＋BCL.D) and distrilled water mixed with refined Bambusae Caulis in Liquamen(DW＋BCL.D) were given orally for 28days respectively. And then, experemental groups were observed in terms of blood sugar, creatinine, BUN and GPT. The amount of glucose was significantly decreased in the Bambusae Caulis in Liquamen and Mixed extracts(Bamboo Juice) with Bambusae Caulis in Liquamen-treated groups compared with the control group(P<0.01). The amount of creatinine, BUN and GPT did not show any differences among Control, BJ＋BCL.D and DW＋BCL.D groups. In conclusion. it was found that Bambusae Caulis in Liquamen and Mixed extracts(Bamboo Juice) with Bambusae Caulis in Liquamen were nontoxic to kidney and liver and also effective on murine hyperglycemia induced with STZ. Mixed extracts(Bamboo Juice) were more effective for decreasing blood glucose than Bambusae Caulis in Liquamen D. BJ＋BCL.D can be used as optimal mix material with Bambusae Caulis in Liquamen D for control Diabetes.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.3
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• pp.532-536
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• 2002

Jookrhyuk (Bambusae Caulis in Liqamen) was extracted at low temperature (100℃ - 160℃) and purified by adsorption and distillation and their physicochemical properties were compared. In case of colour among all Jookrhyuk samples the L value appeared to be higher in the purified Jookrhyuk,and the b value appeared to be higher in crude Jookrhyuk. Purified Jookrhyuk showed much lower level of total sugar and tar contents than crude Jookrhyuk. A considerable reduction in concentration of methanol and phenolic compounds was achieved by purification process, whereas the content of acetic acid was increased. Therefore it was suggested that adsoption and distillation could be used as one of effective purification methods of various Joockrhyuk samples.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.6
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• pp.1253-1259
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• 2002

This study was carried out to investigate the effects of Bambusae Caulis in Liquamen from different production process on blood sugar of the diabetic mice induced with Streptozotocin(STZ). The original Bambusae Caulis in Liquamen filtered and refined. Bambusae Caulis in Liquamen D(H-BCL.D) extracted at high temperature(1000℃), Bambusae Caulis in Liquamen A(L-BCL.A) and Bambusae Caulis in Liquamen B(L-BCL.B) extracted at low temperature (250～450℃) were administerd to mice for 4weeks and its anti-diabetic effect examined. Mice used in this experiment were divided into four groups(Control, H-BCL.D, L-BCL.A and L-BCL.B). Experemental groups were observed in terms of blood sugar, Creatinine, BUN and GPT. The amount of glucose was significantly decreased in the Bambusae Caulis in Liquamen-treated groups compared with the control(P < 0.05). The amount of Creatinine did not show any differences among four groups. The amount of Blood Urea Nitrogen did not show any differences in the L-BCL.A and B-treated groups, but did show slightly decrease(P<0.05) at H-BCL.D-treated group. The amount of GPT did not show any differences among four groups. In conclusion, it was found that Bambusae Caulis in Liquamen from extracted at high or low temperature were effective on murine hyperglycemia mice induced with STZ respectively.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.5
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• pp.1217-1223
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• 2003

This study was carried out to understand the effects of Bambusae Caulis in Liquamen manufactured by different production process mixed with Silk Worm Powder on blood sugar in the db/db mice. Refined Bambusae Caulis in Liquamen D(L-BCL.D and H-BCL.D) manufactured by low or high temperature production process and original Bambusae Caulis in Liquamen producted by Hanlim pham Co. (BCL) and Silk Worm Powder were used. The effects of L-BCL.D+Silk Worm Powder, H-BCL.D+Silk Worm Powdr and BCl+SWP were observed in terms of blood sugar, creatinine, BUN, GPT in db/db mice. The amount of glucose was significantly decreased (P < 0.01) in the expremental groups compared with the control. The amount of Creatinine did not show any differences among four groups. The amount of blood urea nitrogen observed significant decrease in the case of BCL group. The amount of GPT did not show any differences among four groups.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.1
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• pp.177-182
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• 2003

This study was carried out to understand the effects of Bambusae Caulis in Liquamen on blood sugar in the db/db mice. Refined Bambusae Caulis in Liquamen C. D(BCL.C. D)manufactured by high temperature production process and Bambusae Caulis in Liquamen(H-BCL) manufactured & distributed by HANLIM PHARM.COM., LTD were used. The Bambusae Caulis in Liquamen extracted from bamboo charooal manufacturing process was filtered and refined. The effects of Bambusae Caulis in Liquamen were administered orally to mice for 6weeks and its anti-diabetic effect examined. The effects of BCL.C. D and H-BCL were observed in terms of blood sugar. creatinine. BUN and GPT in db/db mice. The results were as follows : The amount of glucose was slightly decreased (P<0.05) in the B CL.C-treated groups compared with the control. The amount of glucose was significantly decreased (P<0.01) in the BCL.D and H-BCL-treated groups compared with the control. The amount of creatinine did not show any differences among four groups. The amount of blood urea nitrogen did not show any differences in the case of BCL.C-treated groups. but observed significant decrease in the case of BCL.D and H-BCL-treated groups. The amount of GPT did not show any differences in the case of BCL.D-treated groups. but observed significant increase in the case of BCL.C and H-BCL-treated groups.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.1
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• pp.152-158
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• 2005

This study was carried out to understand the physiological properties and the effects of Bambusae Caulis in Liquamen manufactured by three different production process on blood glucose of the mice induced with streptozotocin. Original, filtered and refined Bambusae Caulis in Liquamen manufactured by three different production process were used. The physiochemical properties of original, filtered and refined Bambusae Caulis in Liquamen manufactured by three different production process were compared. Furthermore, the effects of original, filtered and refined Bambusae Caulis in Liquamen were observed in terms of blood glucose, BUN, ALT in the mice induced with streptozotocin. The results were as follows : The range of the pH manufactured by three different production processes was $2.28{\sim}3.17$ Concentration of methanol and phenolic compounds which are related to toxicity were lowest in filtered Bambusae Caulis in Liquamen(L-BCL [E] B) manufactured by using electric furnace at $215{\circ}C$ during 8.10/hour. The blood glucose contents was decreased in the experimental groups compared with the control. The amount of BUN and ALT did not show any differences between control and experimental group.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.5
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• pp.1456-1462
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• 2004

This study was carried out to understand the effects of Bambusae Caulis in Liquamen manufactured by different production facilities on blood glucose of the mice induced with streptozotocin. Filtered Bambusae Caulis in Liquamen manufactured by two different facilitiesproduction process were used. The physiochemical properties of filtered Bambusae Caulis in Liquamen manufactured by two different facilities(300L×300W×400H and 700L×700W×800H electric furnace) were compared. Furthermore, the effects of filtered Bambusae Caulis in Liquamen were observed in terms of blood glucose, BUN and AL T in the mice induced with streptozotocin. The results were as follows : The pH value was the highest in L-BCL(E)B(pH 2.83) between manufactured by two different facilities. The L-BCL(E)B which observed low values of Hunter's color values show decreased concentration of methanol and phenolic compounds. The blood glucose contents was decreased in the experimental groups compared with the control. The amount of BUN and ALT did not show any differences between control and experimental group.