• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.175-177
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• 2016

Breast cancer is the most common cancer among the population as a whole and among females, yet it is highly curable if diagnosed at an early stage. Different methods are used to diagnose breast cancer. One of these methods features immunological tests using flow cytometry to determine T-lymphocyte (CD4/CD8) ratios in peripheral blood. One hundred patients with breast cancer (50 from Basra, Iraq, and 50 from Baku, Azerbaijan) confirmed to have breast cancer by histopathology were studied. Blood samples were collected from all patients before initiation of treatment and were used for analysis. The mean age of women from Basra was $51.2{\pm}10.7years$ and that of women from Baku was slightly higher at $54.8{\pm}12.2$. The mean CD4/CD8 ratio in Basra was 1.4 and in Baku was 1.8 with P value < 0.05. The percentage of Basra patients who have CD4/CD8 value less than 1 was 50%, while the percentage for Baku patients was 24 % (p < 0.05). While the CD4/CD8 T-lymphocyte ratio might be useful for early diagnosis in patients with breast cancer parallel with other confirmed tests factors involved in explaining variation between countries such as that observed here need to be taken into account.

• Acta Via Serica
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• 제2권1호
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• pp.109-120
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• 2017

The city of Basra, established on the shore of Basra Bay in the south of modern Iraq, played an important role in agriculture and trade for centuries, with its geography and its position where two great rivers of Mesopotamia flow. Before being established with its current name by the Muslim Arabs, the city was known as Teredon in the Chaldean period and VehiŞtebad ErdeŞir in the Sasanid period. It was reestablished with the name Basra in the early period of Islam by Arabs between Hijri 14-16 (635-637 CE). Afterward, the city became one of the most important centers of trade, science and thought; had a perfect cultural diversity; and hosted important schools of Arabic language and thought for centuries. Besides the commercial effects of its being a transfer point on the axis of Europe, Mesopotamia, Iran, and India, the schools of thought which emerged here were affected by this mobility. In this paper, we try to reveal the philosophical-religious approach which the Ikhwan al-Safa school of thought in Basra, one of the most important cities of the Silk Road, created in parallel with the characteristics of this city. Shiite Ismaili beliefs and thoughts in the region and its characteristics which feed different religions and traditions emerging from Egypt and with the scientific approach of Greek thought; with Indian-Iranian teachings that merge Greek thought and Neoplatonic philosophy, give us the summary of Silk Road civilizations.

• 대한화학회지
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• 제54권5호
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• pp.506-514
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• 2010

benzoylisothiocyanate 와 아스파르트산 [BATA] (1), 글루탐산 [BATG] (2), 메티오닌 [BATM] (3), 루신 [BATL] (4), 및 트립토판 [BATT] (5) 등의 다양한 아미노산을 반응시켜 일련의 새로운 리간드인 N-[(benzoylamino)-thioxomethyl]-amino acid (HL)를 합성하였다. 이들 리간드의 특성을 원소분석, IR 및 NMR로 규명하였다. 이러한 리간드 (6-8)의 몇가지 전이금속 착물을 제조하여[M = Cu(II), Co(II), 또는 Ni(II)] 원소분석, IR 및 $^1H$ NMR을 통하여 특성을 규명하였다. 항균성에 대한 연구 결과 모든 리간드가 항균 활성을 보이지 않는 반면, ($ML_2$) 착물; [M=Cu(II),Co(II), 또는 Ni(II)]은 (Gram -ive) Escherichia (NCTC5933) 및 (Gram +ive) Staphylococcus (NCTC6571)에 대해 항균 활성을 보였으며 또한 (BALB/C) 알비노 쥐에 대해 독성을 보이지 않았다.

• 한국재료학회지
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• 제34권3호
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• pp.144-151
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• 2024

This work focuses on the fabrication of excellent magnetic structures for trapping breast cancer cells. Micromagnetic structures were patterned for trapping cancer cells by depositing 30 nm of permalloy on a silicon substrate. These structures were designed and fabricated using two fabrication techniques: electron beam lithography and laser direct writing. Two types of magnetic structures, rectangular wire and zig-zagged wire, were created on a silicon substrate. The length of each rectangular wire and each straight line of zig-zagged wire was 150 ㎛ with a range of widths from 1 to 15 ㎛ for rectangular and 1, 5, 10 and 15 ㎛ for zigzag, respectively. The magnetic structures showed good responses to the applied magnetic field despite adding layers of silicon nitride and polyethylene glycol. The results showed that Si + Si₃N₄ + PEG exhibited the best adhesion of cells to the surface, followed by Si + Py + Si₃N₄ + PEG. concentration of 5-6 with permalloy indicates that this layer affected silicon nitride in the presence of Polyethylene glycolPEG.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3035-3041
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• 2016

Breast cancer (BC) is the most common malignancy of women worldwide. In the past it was considered as disease of older middle aged women, but the incidence of BC in young females is growing in recent years concordant with studies in Pakistan. In this paper, we reviewed the mutant functions of tumor suppressor genes (BRCA1, BRCA2, p53, ATM and PTEN), epigenetic transformation and involvement of estrogen receptors in development of breast cancer. We further reviewed the current situation of BC in Pakistan that depicts a higher incidence in young females. According to SKMCH and RC data, age group 45-49 years is more prone to BC with high rate of incidence 45.42%. A few studies explored the high expression of ER, PR and HER-2/neu in Pakistani females. Moreover, presence of BRCA1 (c.1961dupA) mutation in Pakistani shows concordance with data in different areas of world. But we are unable to find an authentic study that can explore epigenetic based transformation of breast tumors in Pakistan. This area of research needs more attention to explore the complete picture of BC in Pakistan.

• 비교문화연구
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• 제36권
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• pp.241-270
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• 2014

The aim of this article is to review the traditional methodologies of teaching translation that concentrate on text-typologies and, as an alternative, to propose an eclectic multi-componential approach that involves a set of interdisciplinary skills with a view to improving the trainee translators' competences and skills. To this end, three approaches, namely a minimalist approach, a pre-transferring adjustment approach and a revision vs. editing approach are proposed to shift the focus of attention from teacher-centred approaches towards student-centred approaches. It has been shown that translator training programmes need to focus on improving the trainee translators' competences and skills, such as training them how to produce and select among the different versions they produce by themselves with justified confidence as quickly as they can (minimalist approach), adjust the original text semantically, syntactically and/or textually in a way that the source text supplely accommodates itself in the linguistic system of the target language (pre-transferring adjustment), and revise and edit others' translations. As the validity of the approach proposed relies partially on instructors' competences and skills in teaching translation, universities, particularly in the Arab world, need to invest in recruiting expert practitioners instead of depending mainly on bilingual teachers to teach translation.

• International Journal of Computer Science & Network Security
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• 제23권6호
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• pp.193-201
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• 2023

In this paper, we consider the maximum scatter traveling salesman problem (MSTSP), a travelling salesman problem (TSP) variant. The problem aims to maximize the minimum length edge in a salesman's tour that travels each city only once in a network. It is a very complicated NP-hard problem, and hence, exact solutions can be found for small sized problems only. For large-sized problems, heuristic algorithms must be applied, and genetic algorithms (GAs) are found to be very successfully to deal with such problems. So, this paper develops a hybrid GA (HGA) for solving the problem. Our proposed HGA uses sequential sampling algorithm along with 2-opt search for initial population generation, sequential constructive crossover, adaptive mutation, randomly selected one of three local search approaches, and the partially mapped crossover along with swap mutation for perturbation procedure to find better quality solution to the MSTSP. Finally, the suggested HGA is compared with a state-of-art algorithm by solving some TSPLIB symmetric instances of many sizes. Our computational experience reveals that the suggested HGA is better. Further, we provide solutions to some asymmetric TSPLIB instances of many sizes.

• Corrosion Science and Technology
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• 제23권1호
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• pp.20-32
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• 2024

Metal corrosion in acidic environments is a major issue in various industrial applications. This study evaluates the 4-piperonylideneaminoantipyrine (PPDAA) corrosion inhibition efficiency for mild steel in a hydrochloric acid (HCl) solution. The weight loss method was used to determine the corrosion inhibition efficiency at different concentrations and immersion time periods. Results revealed that the highest inhibition efficiency (94.3%) was achieved at 5 mM concentration after 5 hours of immersion time. To inspect the surface morphology of the inhibitor film on the mild steel surface, scanning electron microscopy (SEM) was used before and after immersion in 1.0 M HCl. Density functional theory (DFT) calculations were performed to investigate the molecular structure and electronic properties of the inhibitor molecule to understand the corrosion inhibition mechanism. Theoretical results showed that the inhibitor molecule can adsorb onto the mild steel surface through its nitrogen and oxygen atoms, forming a protective layer that prevents HCl corrosive attack. These findings highlight the potential of PPDAA as an effective corrosion inhibitor for mild steel in HCl solution. Moreover, combining experimental and theoretical approaches provides insights into the mechanism of corrosion inhibition, which is essential for developing effective strategies to prevent metal corrosion in acidic environments.

• Journal of Applied Biological Chemistry
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• 제65권4호
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• pp.329-335
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• 2022

Essential minerals are important for human health because they support biochemical reactions in metabolism and may play a role in the development of glucose-6-phosphate dehydrogenase deficiency (G6PD). We investigated the relationship between calcium, magnesium, urea, creatinine, total protein, glucose and vitamin D levels in G6PD deficiency in this study. The control group consisted of 40 people (23 females and 17 males) and the patient group consisted of 50 people (20 females and 30 males), all of whom were between the ages of (1-12 years). The findings revealed that the calcium level in patients, depending on sex factor, has a highly significant increase (p <0.0001) when compared to the control group, especially in children who are females rather than males who are affected by G6PD deficiency. In addition, the level of magnesium was found to be significantly different (p <0.0001) in children male patients when compared to the control group. On the other side, the level of total protein was found to be significantly high in children patients (p <0.01) when comparing with control group, and the levels of urea, creatinine and glucose were found to be highly significant increase (p <0.001) in patients when comparing to healthy groups, vitamin D levels were significantly lower (p <0.0001) with G6PD deficiency comparing to control group. In conclusion, the low and high significant associations between vitamin D, calcium, magnesium, urea, creatinine, and glucose indicate that more research is needed to better understand their roles in G6PD development.