• 동의생리병리학회지
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• 제16권3호
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• pp.567-571
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• 2002

In order to prove the sedative, anticonvulsive effects of Incenses and to identify the effect of this medicine to cerebral glutamic acid and GABA density in experimental animal. we used Incense which was made of traditional herb medicines. We also examined what kind of material is to be involved in biosynthesis of these elements. In addition we experimented to find out synthesis of active GABA-T. Incenses were inhaled 8 hours a day for 4 weeks to mice. Finally we have following results. On the convulsion induced by pentylenetetrazole(PTZ), Incenses showed significant anticonvulsive effect. Density of glutamic acid in brain was significantly decreased. On the contrary, density of GABA was significantly increased. The Activity of GABA- T in brain was significantly reduced. The quantity of lipid peroxide in the brain was significantly decreased. Activity of xanthine oxidase and aldehyde oxidase were significantly reduced in brain. From the above results, we confirmed that Incenses decreased the density of glutamic acid, increased GABA density and decreased the activity of GABA- T in brain. For the convulsion which was induced by PTZ, Incenses showed significant anticonvulsive effect. With this we can recognize that Incenses had ability to control the quantity of lipid peroxide in brain. In the conclusion, Incenses has significant anticonvulsive effect, so I strongly recommend to prescribe Incenses to treat convulsive disorder like epilepsy.

• 한국지반공학회논문집
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• 제28권10호
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• pp.17-25
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• 2012

NATM공법을 적용한 터널에서 숏크리트, 락볼트, 강지보재 등은 터널 굴착 후에 지반을 지지하기 위해 설치되는 주요한 지보재이다. 이전에는 H형강 지보재와 같은 강지보재가 많이 사용되었지만, 시공성이 떨어지는 등의 문제가 있어 격자지보재의 사용이 증가하였다. 본 연구에서는 기존의 격자지보재에서 스파이더와 강봉간의 접촉면적을 넓혀 강도가 증진된 신형 격자지보재를 개발하여 그 효과 및 성능을 검증하고자 LG-$50{\times}20{\times}30$, LG-$70{\times}20{\times}30$, LG-$95{\times}22{\times}32$ 세 가지 규격으로 3점 휨강도 실험과 4점 휨강도 실험을 실시하였다. 그 결과 기존의 격자지보재와 비교하여 신형의 격자지보재는 스파이더와 주강봉 접촉부에서는 평균 17.95%의 강도증진 효과가 있었고, 스파이더와 스파이더 사이에서는 평균 19.37%의 강도증진 효과가 있었으며 이는 스파이더와 주강봉 사이의 기계적 결합과 접촉면적 증가에 의한 격자지보재의 강성증가에 따른 결과로 사료된다.