• Journal of Sasang Constitutional Medicine
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• v.21 no.3
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• pp.17-29
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• 2009

1. Objectives: We study on indications and directions of Euphorbiae Kansui Liou ex Wang in Sasang Constitutional Medicine by applications of Euphorbiae Kansui Liou ex Wang. 2. Methods: We analyzed indications and directions by bibliographical applications of Radix Euphorbiae Kansui Liou ex Wang in Traditional Oriental Medicine and Sasang Constitutional Medicine. 3. Results and Conclusions: 1) Euphorbiae Kansui Liou ex Wang is used for various indications which are congested fluids, accumulation, edema, and etc in Traditional Oriental Medicine and Sasang Constitutional Medicine. 2) In Sasang Constitutional Medicine, Euphorbiae Kansui Liou ex Wang is taken by powder in a single-medicine prescriptions and taken with calomelas by powder and tablet in prescriptions, and we have need of clinical study of Radix Euphorbiae Kansui in the future.

• Journal of Sasang Constitutional Medicine
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• v.30 no.2
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• pp.64-73
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• 2018

Objectives We report 1 treatment case with Euphorbiae Kansui Radix which is based on Sasang constitutional Medicine for Chronic Dizziness in Soyangin. Methos We treated Soyangin patient suffering form chronic dizziness. We prescribed Euphorbiae Kansui Radix for her physical symptoms. The improvement of her dizziness was evaluated by Visual Analogue Scale(VAS). Results After the Euphorbiae Kansui Radix was given, the patient's Dizziness was improved. And there was not any adverse effect. Conclusions This study shows that using Euphorbiae Kansui Radix can be effective treatment for Soyangin chronic dizziness patient.

• Journal of Sasang Constitutional Medicine
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• v.23 no.4
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• pp.541-547
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• 2011

1. Objective We report a series of 3 cases Euphorbiae Kansui. Radix(Gam-sui) which is based on Sasang constitutional Medicine for Tension-Type Headache in Soyangin. 2. Methods We treated a 3 Soyangin patients that had Tension-Type Headache. We prescribed Euphorbiae Kansui. Radix(Gam-sui) for their physical symptoms. The improvement of their Tension-Type Headache was evaluated 3. Results After the Euphorbiae Kansui. Radix(Gam-sui) was given, the patient's Headache and physical symptoms were improved. 4. Conclusions This cases studies showed an efficient result of using Euphorbiae Kansui. Radix(Gam-sui) in the Tension-Type Headache of Soyangin.

• Journal of Sasang Constitutional Medicine
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• v.27 no.3
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• pp.333-345
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• 2015

Objectives We report a series of 2 cases which is based on Sasang constitutional Medicine for Atopic dermatitis in Soyangin using oriental medeicine therapy with Euphorbiae Kansui. Radix (Gam-sui) Methods We treat 2 Soyangin patients that had Atopic dermatitis. We prescribed oriental medeicine therapy with Euphorbiae Kansui. Radix (Gam-sui) for their physical symptoms. The improvement of their Atopic dermatitis was evaluated. Results After using oriental medeicine therapy with Euphorbiae Kansui. Radix (Gam-sui), patients' physical symptoms were improved. Conclusions These case studies showed an efficient result of using oriental medeicine therapy with Euphorbiae Kansui. Radix (Gam-sui) in the Atopic dermatitis of Soyangin.

• The Journal of Korean Medicine
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• v.21 no.1
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• pp.103-108
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• 2000

Paralytic ileus is one of the gastro-intestinal symptoms of a patient who is in the post-symptom period resulting from stroke. The purpose of this study was to examine the efficacy of Euphorbiae Kansui Radix(Gan-sui) for a patient who has suffered from severe paralytic ileus as post-symptoms caused by 3rd stroke. The subject was a 70-year-old woman who had been troubled with dyspepsia, abdominal flatus and other pains during the past 10 years, and whose symtoms worsened because of her recent 3rd stroke. At the time of admission, she complained of abdominal flatus, conspitation, quadri weakness(Lt>Rt) and dysathria. For the first 10 days after admission, she was treated with Oriental' Western Medicine, which failed to relieve any symptom. However, after taking Euphorbiae Kansui Radix(Gan-sui), gastro-intestinal vermicular movement improved, so the symptoms of abdominal flatus and conspitation disappeared. As a consequence, the accompanying paralytic ileus condition also improved.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.6
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• pp.593-600
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• 2014

This study is aimed to investigate the anti-inflammatory effect of Euphorbiae kansui radix methanol extract (ERE) in lipopolysaccharide(LPS)-stimulated mouse peritoneal macrophages. Peritoneal macrophages were obtained from thioglycollate-injected Balb/c mice. Cells were stimulated with LPS or LPS plus interferon-gamma (IFN-${\gamma}$) in the presence of ERE and various inflammatory markers were assayed. Finally, LPS-induced signaling molecules were measured. ERE up to $400{\mu}g/m{\ell}$, was not cytotoxic to ERE inhibited LPS/IFN-${\gamma}$-induced nitric oxide (NO), inducible NO synthase. ERE also reduced the levels of cyclooxygenase-2 and the proinflammatory cytokines such as tumor necrosis factor-${\alpha}$, interleukin(IL)-6 and IL-12. The inhibitory effect of ERE on LPS-induced $I{\kappa}B{\alpha}$ degradation was weak but phosphorylation of JNK, p38 and ERK1/2 was strongly suppressed. Our data indicated that the anti-inflammatory effect of ERE in LPS-stimulated macrophages was partly mediated by its inhibition of JNK, p38 and ERK1/2.

• Journal of Sasang Constitutional Medicine
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• v.34 no.2
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• pp.65-74
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• 2022

Objective In this study, we report significant improvement of edema patient who was diagnosed with Soyang person chest bind syndrome/pattern based on Sasang Constitutional Medicine. Methods The patient was identified as Soyang person chest bind syndrome/pattern and treated with Hyeongbangjihwang-tang-ga-moktong and Euphorbiae Kansui. Radix(Gam-sui). To evaluate the results of this treatment, the patient assessed edema by using the Numeral Rating Scale(NRS). Result and Conclusion After treatment with Hyeongbangjihwang-tang-ga-moktong and Euphorbiae Kansui. Radix(Gam-sui), patient's symptms were improved. This study shows that Sasang Constituitional medicine can be effective treatment for edema.

• Journal of Sasang Constitutional Medicine
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• v.20 no.2
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• pp.1-10
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• 2008

1. Objectives I investigated the effects and mechanisms of Semen Tiglii(ST, 巴豆), Radix Euphorbiae Kansui(REK, 甘遂) and Pedicelus Melo(PM, 瓜莘) in the view of Sasang Constitutional Medicine. 2. Methods I analyzed the literature about oriental medicine and Sasang Constitutional medicine related to herbal Medicine. The contents analyzed were efficacious disease, dosage, usage, side effect, toxicity. 3. Results The first, similarities of ST, REK and PM are improving Gwangyuk, the Chest Discomfort with Constipation, Dysuria and Nausea, toxic, used in urgency, asministered by itself and used shaped powder. The second, ST and REK used the diseases related water and food metabolism in Soumin and Soyangin. PM used the diseases related Qi and fluid metabolism in Taeumin. The third, diarrhea caused by ST and REK is symptom to retrieve the diseases related water and food metabolism. The vomiting caused by PM is symptom to retrieve the diseases related Qi and fluid metabolism. 4. Conclusions The ST, REK and PM is good herbal medicine (() retrieve the urgency symptom caused by the body unbalance in Sasang Constitutional Medicine. The proper dosage is essential because of toxicity of drugs.

• Journal of Korean Medicine Rehabilitation
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• v.25 no.1
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• pp.53-61
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• 2015

Objectives The purpose of this study is to compare the common herbs for pain related disease between Yak-Jing and textbook of herbology. Methods We searched the formation of "Koho" and theory of Todo yoshimasu. We selected the common herbs that is used for pain related disease in Yak-Jing and textbook of herbology. These herbs were compared with each other. Result 1. Common Herbs for pain related disease are Ephedrae Herba (麻黃), Aconiti Lateralis Preparata Radix (附子), Euphorbiae Kansui Radix (甘遂), Euphorbiae pekinensis Radix (大戟) Daphnis Genkwa Flos (芫花), Atractylodis Rhizoma (朮), Paeonia Radix Rubra (芍藥), JujubaeFructus (大棗), Gypsum (石膏), Anemarrhenae Rhizoma (知母), Cinnamomi Ramulus (桂枝), Poria (茯苓), Rhei Rhizoma (大黃), Natrii Sulfas (芒草), Pueraiae Radix (葛根). There are some difference between textbook of herbology and Yak-Jing about Aconiti Lateralis Preparata Radix (附子), Paeonia Radix Rubra (芍藥), Atractylodis Rhizoma (蒼朮), Pueraiae Radix (葛根). 2. Preparata Radix (附子) excrete water poisons (水毒) in Yak-Jing, but it has the effect of restore yang and tonify fire (回陽補火) in textbook of herbology. 3. Paeonia Radix Rubra (芍藥) is effective for pathological condition caused by the formation of the band and spasm (結實拘攣) in Yak-Jing, but it is to cure heat pattern in textbook of herbology. 4. Atractylodis Rhizoma (蒼朮) has the effect of water-draining (利水) in Yak-Jing, but it has the effect of dispersing (發散) in textbook of herbology. 5. Pueraiae Radix (葛根) is used in dyspnea and sweating (喘而汗出) in Yak-Jing, but it is to cure engender fluid (生津), skin disease, diarrhea in textbook of herbology. Conclusion There are some difference between textbook of herbology and Yak-Jing in the herb medicine that is used in pain related disease.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.4
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• pp.153-164
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• 2005

Purpose : This study was designed to make a basis of in vivo or clinical study about colporrhea. Methods : This study is based on Yang's study, An investigation on the prescriptions of colporrhea(1999). We investigate the prescriptions in the Yang's study and examine the frequency of metioned single herb. Also we investigate the herb's classification. Results and Conclusion : 1) Single herb frequently used in the prescriptions was as follows. (()- Frequency) Paeoniae Radix Alba白芍藥(16), Glycyrrhizae Radix甘草(15), Poria白茯?(13),　Angelicae gigantis Radix當歸, Citri Pericapium陳皮(11), Atractylodis macrocephalae Rhizoma白朮(10), Zingiberis Rhizoma乾薑　, Atractylodis Rhizoma蒼朮, Ailanthi Cortex樗根白皮, Phellodendri Cortex黃柏, Ginseng Radix人蔘, Cyperi Rhizoma香附子(9),　Dioscoreae Rhizoma山藥, Corni Fructus山茱萸, Bupleuri Radix柴胡, Cnidii Rhizoma川芎, Gardeniae Fructus梔子(8), Rehmanniae Radix preparat熟地黃, Pinelliae Rhizoma半夏(7), Foeniculi Fructus小茴香, Scutellariae Radix黃芩, Angelicae dahuricae Radix白芷, Cinnamomi肉桂(5), CortexAlismatis Rhizoma澤瀉, Moutan Cortex牧丹皮, Aconiti iateralis preparata Radix附子, Plantaginis Semen車前子(4), Ostreae Concha牡蠣, Euphorbiae pekinensis Radix大戟, Aucklandiae Radix木香, Rhei Radix et Rhizoma大黃, Ledebouriellae Radix防風, Astragali Radix黃?, Rehmanniae Radix生地黃, Daphnis genkwa Flos莞花, Evodiae Fructus吳茱萸, Euphorbiae kansui Radix甘遂(3) 2) Herbs specifically frequently used in the prescriptions of colporrhea were as follows. Atractylodis Rhizoma蒼朮, Ailanthi Cortex樗根白皮, Phellodendri Cortex黃柏, Cyperi Rhizoma香附子, Bupleuri Radix柴胡, Gardeniae Fructus梔子　3)Herbs frequently used were classified by herbal medicine's classification. The　result was as follows. (()-The number of herbs)　補益藥（1９). 淸熱藥(18). 解表藥(10), 收澁藥(9), 溫裏藥(7), 理氣藥(6), 利水?濕藥(6), 瀉下藥（５)