• Korean Journal of Microbiology
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• v.35 no.4
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• pp.258-265
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• 1999

Entry into meiosis in the yeast Saccharomyces cerevisiae is regulated by two major factors: the cell type MATa/MAT${\alpha}$ and the nutriational state (starvation) of the cell. The two independent regulations act through IME1and IME2 expression to initiate meiosis. IME2 encodes a meiosis-specific protein kinase, and it enabled MATa/MAT${\alpha}$ diploid cells to undergo meiosis and sporulation. The PCR mutagenesis method was applied for the isolation of thermosensitive ime2 mutants. Among sixty two mutants isolated from the phenotype of defective spore formation under the restrictive temperature, three with the most easily observed temperature-sensitive phenotype (ts ${\cdot}$ime2-11, ts ${\cdot}$ime2-12 and ts ${\cdot}$ime2-13) were selected for further study. To understand the detailed functions of IME2, we examined the defects of these mutants in the early meiotic pathway including the premeiotic DNA replication and exhibited decreased level in meiotic recombination. These results suggest that the IME2 gene plays essential role in meiotic recombination pathway as well as premeiotic DNA replication. As the result of the IME2 overexpression in ${\Delta}$mre4. moreover, it was suggested that the IME2 and MRE4 genes act on the same pathway of initiation step in meiotic recombination.

• The Journal of Korean Academy of Prosthodontics
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• v.31 no.4
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• pp.625-642
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• 1993

Whether stress-absorbing elements are functional in an implant system has been an issue of interest in oral implantology. The unique feature of the IMZ implant system is the planned imitation of the stress-distributing function of the structural unit of the tooth, periodontium, and alveolar bone through the use of an intramobile element(IME). The purpose of this study was to compare the difference in the displacement and the stress distibutions of IMZ implant with a polyoxymethylene(POM) or a titanium IME under static load. Two dimensional finite element analysis(FEA) was applied for this study and two finite element models were created. PATRAN program(DPA Co.,USA), a software for FEA, and SUN-SPARC2GX(SUN Co., USA), a workstation computer, were used. $1Kg/mm^2$ of static load was loaded individually on each three point of crown of implant prosthesis ; central fossa(load 1), mesial cusp tip(load 2), distal cusp tip(load 3), The displacements of X- and Y-axis and total displacement were measured at mesial and distal cusp tips, mesial and distal points between crown and IME, and implant apex. The von Mises stress was measured at mesial and distal points between crown and IME, mesial and distal points between IME and TIE, mesial and distal alveolar crest, the mesial and distal midpoints of implant, and implant apex. The difference in resultant values were compared and evaluated statistically using paired t-test. The results were as follows : 1. Under the load 1, all the displacement of implant with titanium IME at 5 measuring points was larger than that of with POM IME except total and Y-axis displacement at implant apex. And the differences in stress distributions with POM and titanium were varied. 2. Under the load 2, all the displacement of implant with titanium IME at 5 measuring points was larger than that of with POM IME except X-axis displacement at distal cusp tip. And the differences in stress distributions were varied. 3. Under the load 3, all the displacement of implant with titanium IME at 5 measuring points was larger than that of with POM IME except Y-axis displacement at mesial cusp tip. And the differences in stress distributions were varied. 4. For the displacement, there was significant difference statistically only in total displacement (P<0.1), but was no significant difference in X- and Y-axis displacement(P>0.1). For the stress, there was no significant difference among the compared values.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.7C
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• pp.726-732
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• 2003

The paper proposes a motion estimation (ME) technique to reduce computational complexity. It is achieved by skipping ME process for macro-blocks decided to be in no need of the operation. Thus, it is called ME skipping technique(MEST). In general, the ME is composed of integer pixel precision ME (IME) followed by half pixel precision ME (HME). The MEST is performed just before an IME process and makes a decision on skipping the IME process according to a criterion based on ME errors of adjacent macro-blocks (MBs) already encoded. When the IME process for a MB is decided to be skipped, which is called ME skip mode, the IME process is skipped and the integer pixel precision motion vector of the MB is just replaced by a predicted vector and used as the input of HME. On the other hands, the IME processes for MBs in ME non-skip mode are not skipped but normally performed. Accordingly, the MEST is very effective to reduce computational complexity when MBs in ME skip mode is abundant. In addition, when the MEST is applied to video encoder, it contributes to more accurate rate control and more robusaess for channel errors. It is experimentally shown that the MEST has the above advantages while maintaining good reconstructed image quality.

• IEIE Transactions on Smart Processing and Computing
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• v.3 no.6
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• pp.397-403
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• 2014

A new video compression standard called High Efficiency Video Coding (HEVC) has recently been released onto the market. HEVC provides higher coding performance compared to previous standards, but at the cost of a significant increase in encoding complexity, particularly in motion estimation (ME). At the same time, the computing capabilities of Graphics Processing Units (GPUs) have become more powerful. This paper proposes a parallel integer-pel ME (IME) algorithm for HEVC on GPU using the Compute Unified Device Architecture (CUDA). In the proposed IME, concurrent parallel reduction (CPR) is introduced. CPR performs several parallel reduction (PR) operations concurrently to solve two problems in conventional PR; low thread utilization and high thread synchronization latency. The proposed encoder reduces the portion of IME in the encoder to almost zero with a 2.3% increase in bitrate. In terms of IME, the proposed IME is up to 172.6 times faster than the IME in the HEVC reference model.

• The Korean Journal of Pain
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• v.23 no.1
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• pp.28-34
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• 2010

Background: An independent medical examination (IME) is a critical process for awarding reparation for injury. However, conducting an IME in pain medicine is very difficult, not only because pain is a subjective symptom, but also because there are no proper objective methods to demonstrate it. This study was conducted to compare IME reports and the court decisions on the disability status of the patients. Methods: We analyzed 79 IME reports and 25 corresponding court decisions on the disability status of patients. The diagnoses, causal relationships between the patients' status and the trauma, McBride's degree of disability, the American Medical Association's impairment ratings, the estimated annual cost for future treatment, and the necessity of care-giving were compared and analyzed. Results: The diagnoses in the 79 cases were complex regional pain syndrome (CRPS) type I (58 cases), CRPS type II (7 cases), peripheral neuropathy (5 cases), myofascial pain syndrome (4 cases), herniated intervertebral disc (2 cases), and fibromyalgia (1 case). The types of accidents were road traffic accidents (50 cases), military injuries (14 cases), industrial accidents (11 cases), and others (4 cases). The IME reports and the court decisions stated considerably different McBride's degrees of disability (P = 0.014). However, there was no significant difference in the estimated cost for future treatment between the IME reports and the court decisions (P = 0.912). Conclusions: IME reports should be accurate, fair, and based on objective findings. Feedback on IMEs from the court decisions is helpful for reference use.

• Journal of Microbiology and Biotechnology
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• v.20 no.8
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• pp.1179-1184
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• 2010

We report the generation of the first monoclonal antibody that specifically binds to the polysaccharide chitosan. Mice were immunized with a mixture of chitosans, and hybridoma clones were screened for specific binders, resulting in the isolation of a single clone secreting a chitosan-specific IgM, mAbG7. In ELISAs, the antibody could bind to chitosans of varying composition, but demonstrated the highest affinity for chitosans with lower degrees of acetylation (DA) and very poor binding to chitin. We tested the ability of the antibody to bind to chitosan in situ, using preparations of fungal cell walls. Immunofluorescence microscopy confirmed that the antibody bound strongly to the cell walls of fungi with high levels of chitosan, whereas poor staining was observed in those species with cell walls of predominantly chitin or cellulose. The potential use of this antibody for the detection of fungal contamination and the protection of plants against fungal pathogens is discussed.

• Journal of Korean Society of Rural Planning
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• v.20 no.1
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• pp.127-134
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• 2014

This study, in order to complement instability of analysis result stemming from the choice between reference point and comparison point which is pointed out as the defect of shift-share analysis, conducted shift-share analysis using Gross Regional Domestic Product (GRDP) trend of Geumgang area, Chungcheongnam-do for the period from 2000 to 2011. As a result of the analysis, (1) industries that had both the positive Regional Share Effect (RSE) and Industrial Mixed Effect (IME) were service industries such as manufacturing industry, electricity gas, transportation industry, art, etc., which are positively influencing the regional industry. (2) industries that had both the negative RSE and IME were other service industries such as wholesale and retail businesses, lodging industry, food industry, real estate business and leasing service, business service industry, public administration, etc., which provide basic livelihood services for the residents. (3) industries that had the positive RSE and negative IME were agriculture, forestry and fishery industry, mining industry, construction industry, and educational service industry. (4) industries that had the negative RSE and positive IME were info-communications industry, financial and insurance businesses, health industry, etc.

• Journal of Biomedical Engineering Research
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• v.23 no.3
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• pp.227-233
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• 2002

The IME(implantable middle ear) system is Promising due to its ability to free from sound feedback and Produce a good sound quality and intelligibility with low distortion even if it is operated with high gain for severe hearing impaired. The differential electromagnetic vibration transducer. which was developed for using in IME system and has two small magnets attached the same Pole facing in the coil. is not influenced by environmental external magnetic field. Besides, it has high vibration efficiency and good frequency response characteristics. In this Paper, using acoustic model of the transducer and ear model of normal Person. the signal transfer characteristics of the IME system are analyzed and investigated From the differences of the characteristics between normal ear and the IME system, it is Possible that design of the IME system that have the signal transfer characteristics similar to normal person's ear.

• 한국경영정보학회:학술대회논문집
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• 2007.06a
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• pp.764-769
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• 2007

This paper proposes a new model to· evaluate the effectiveness of websites using balanced scorecard (BSC) and weighted formula based methods.fisrt, we Use BSC method to find out the cause-and-effect relationships between the measure and website activities, and our proposed model evaluates website performance from six perspectives: business value, operational excellence, customer value, website interface, management, maintenance, and learning and innovation. Next, we usedformula-based approach to identify what makes website performance low by developing the evaluation formula through investigating website users; finally, case studies of two famous websites are given to show how our method can be used Our evaluation model can not only evaluate website performance but also suggest how to improve performance.

• Journal of Korea Multimedia Society
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• v.21 no.1
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• pp.18-25
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• 2018

In High Efficiency Video Coding (HEVC), integer motion estimation (IME) requires a large amount of computational complexity because HEVC adopts the high flexible and hierarchical coding structures. In order to reduce the computational complexity of IME, this paper proposes the search range reduction algorithm, which takes advantage of motion vectors similarity between different layers. It needs only a few modification for HEVC reference software. Based on the experimental results, the proposed algorithm reduces the processing time of IME by 28.1% on average, whereas its the $Bj{\emptyset}ntegaard$ delta bitrate (BD-BR) increase is 0.15% which is negligible.