• 미생물학회지
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• 제35권4호
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• pp.258-265
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• 1999

출아효모에서는 질소원의 고갈과 MATa/MAT${\alpha}$ 이배체 세포의 감수분열기 특이적인 유전자 발현에 의해 체세포분열기의 G1기에서 감수분열기로의 진행이 결정된다. 이러한 두 경로는 감수분열기 특이적인 IME 유전자군에 의한 전사조절에 의해 활성화되어 감수분열기가 시작된다. 본 연구는 IME2 유전자가 protein kinase 로서 감수분열기의 어떤 과정에 직접 관여하는가를 조사하기 위하여 먼저 PCR mutagenesis를 통하여 온도감수성 ime2 변이주를 분리하였다. 전체 62개의 온도감수성 변이주 중에서 온도에 따른 포자형성능과 감수분열기 재조합 빈도에 대하여 명확한 차이를 나타내는 3종류의 변이주들(ts ${\cdot}$ ime2-11, ts ${\cdot}$ ime2-12와 ts ${\cdot}$ ime2-13)을 선택하였다. 이러한 3종류의 온도감수성 변이주를 이용하여 제한온도에서 감수분열기 초기과정 중 결손을 조사하기 위해, FACScan analysis를 한 결과 IME2유전자가 감수분열기의 DNA 복제과정의 개시 및 완료에 관여함을 알 수 있었고, his4 혹은 arg4 locus에서 감수분열기 재조함 빈도의 측정으로 재조합 과정에 중요한 역할을 한다는 것을 알 수 있었다. 더욱이${\Delta}$mre4 파괴주에 IME2유전자를 과다발현시켜 그 영향을 조사한 결과, 감수분열기 특이적인 protein kinase 인 IME2와 MRE4가 감수분열기 초기과정인 재조합 과정에서는 동일한 경로에 작용한다는 것이 제시되었다.

• 대한치과보철학회지
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• 제31권4호
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• pp.625-642
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• 1993

Whether stress-absorbing elements are functional in an implant system has been an issue of interest in oral implantology. The unique feature of the IMZ implant system is the planned imitation of the stress-distributing function of the structural unit of the tooth, periodontium, and alveolar bone through the use of an intramobile element(IME). The purpose of this study was to compare the difference in the displacement and the stress distibutions of IMZ implant with a polyoxymethylene(POM) or a titanium IME under static load. Two dimensional finite element analysis(FEA) was applied for this study and two finite element models were created. PATRAN program(DPA Co.,USA), a software for FEA, and SUN-SPARC2GX(SUN Co., USA), a workstation computer, were used. $1Kg/mm^2$ of static load was loaded individually on each three point of crown of implant prosthesis ; central fossa(load 1), mesial cusp tip(load 2), distal cusp tip(load 3), The displacements of X- and Y-axis and total displacement were measured at mesial and distal cusp tips, mesial and distal points between crown and IME, and implant apex. The von Mises stress was measured at mesial and distal points between crown and IME, mesial and distal points between IME and TIE, mesial and distal alveolar crest, the mesial and distal midpoints of implant, and implant apex. The difference in resultant values were compared and evaluated statistically using paired t-test. The results were as follows : 1. Under the load 1, all the displacement of implant with titanium IME at 5 measuring points was larger than that of with POM IME except total and Y-axis displacement at implant apex. And the differences in stress distributions with POM and titanium were varied. 2. Under the load 2, all the displacement of implant with titanium IME at 5 measuring points was larger than that of with POM IME except X-axis displacement at distal cusp tip. And the differences in stress distributions were varied. 3. Under the load 3, all the displacement of implant with titanium IME at 5 measuring points was larger than that of with POM IME except Y-axis displacement at mesial cusp tip. And the differences in stress distributions were varied. 4. For the displacement, there was significant difference statistically only in total displacement (P<0.1), but was no significant difference in X- and Y-axis displacement(P>0.1). For the stress, there was no significant difference among the compared values.

• 한국통신학회논문지
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• 제28권7C호
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• pp.726-732
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• 2003

본 논문은 계산량을 줄이는 움직임 추정 (motion estimation: ME) 방법을 제안한다. 이 방법은 움직임 추정이 필요 없다고 판단되는 매크로블록(macro-block: MB)들에 대한 움직임 추정 과정을 생략함으로써 고속의 움직임 추정을 가능하게 한다. 그래서, 제안된 방법은 움직임 생략 기법 (ME skipping technique: MEST)이라고 부른다. 일반적으로 움직임 추정은 정수 화소 단위 움직임 추정 (IME)과 반화소 단위 움직임 추정 (HME)로 구성된다. MEST는 IME 과정 바로 직전에 수행되고, 이미 부호화된 주위의 MB들의 움직임 추정 오차에 기초한 기준에 따라 IME 과정을 생략할지를 판단한다. 하나의 MB에 대한 IME 과정이 생략되는 것으로 판단되었을 경우 (이 경우를 ME 생략 모드 (ME skip mode)라 부른다), IME 과정은 생략되고 그 MB에 대한 정수 화소 단위 움직임 벡터를 예측벡터로 대치한다. 예측된 그 벡터는 HME의 입력으로 사용된다. 한편, ME 생략 모드가 아닌 경우(ME non-skip mode)의 MB들에 대한 IME 과정은 생략되지 않고 보통의 IME과정을 수행하게 된다. 따라서 MEST는 ME 생략 모드로 판단되는 MB들이 많을수록 계산량을 감소시키는데 효과적이다. 뿐만 아니라 MEST가 비디오 부호화기에 적용되었을 경우, 좀 더 정화한 율제어 (rate control)과 채널 오류에 좀 더 강한 비트열 (bitstream)을 제작하는데 도움을 준다. 실험을 통해, MEST가 같은 화질을 유지하면서도 이러한 장점을 가짐을 보인다.

• IEIE Transactions on Smart Processing and Computing
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• 제3권6호
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• pp.397-403
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• 2014

A new video compression standard called High Efficiency Video Coding (HEVC) has recently been released onto the market. HEVC provides higher coding performance compared to previous standards, but at the cost of a significant increase in encoding complexity, particularly in motion estimation (ME). At the same time, the computing capabilities of Graphics Processing Units (GPUs) have become more powerful. This paper proposes a parallel integer-pel ME (IME) algorithm for HEVC on GPU using the Compute Unified Device Architecture (CUDA). In the proposed IME, concurrent parallel reduction (CPR) is introduced. CPR performs several parallel reduction (PR) operations concurrently to solve two problems in conventional PR; low thread utilization and high thread synchronization latency. The proposed encoder reduces the portion of IME in the encoder to almost zero with a 2.3% increase in bitrate. In terms of IME, the proposed IME is up to 172.6 times faster than the IME in the HEVC reference model.

• The Korean Journal of Pain
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• 제23권1호
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• pp.28-34
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• 2010

Background: An independent medical examination (IME) is a critical process for awarding reparation for injury. However, conducting an IME in pain medicine is very difficult, not only because pain is a subjective symptom, but also because there are no proper objective methods to demonstrate it. This study was conducted to compare IME reports and the court decisions on the disability status of the patients. Methods: We analyzed 79 IME reports and 25 corresponding court decisions on the disability status of patients. The diagnoses, causal relationships between the patients' status and the trauma, McBride's degree of disability, the American Medical Association's impairment ratings, the estimated annual cost for future treatment, and the necessity of care-giving were compared and analyzed. Results: The diagnoses in the 79 cases were complex regional pain syndrome (CRPS) type I (58 cases), CRPS type II (7 cases), peripheral neuropathy (5 cases), myofascial pain syndrome (4 cases), herniated intervertebral disc (2 cases), and fibromyalgia (1 case). The types of accidents were road traffic accidents (50 cases), military injuries (14 cases), industrial accidents (11 cases), and others (4 cases). The IME reports and the court decisions stated considerably different McBride's degrees of disability (P = 0.014). However, there was no significant difference in the estimated cost for future treatment between the IME reports and the court decisions (P = 0.912). Conclusions: IME reports should be accurate, fair, and based on objective findings. Feedback on IMEs from the court decisions is helpful for reference use.

• Journal of Microbiology and Biotechnology
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• 제20권8호
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• pp.1179-1184
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• 2010

We report the generation of the first monoclonal antibody that specifically binds to the polysaccharide chitosan. Mice were immunized with a mixture of chitosans, and hybridoma clones were screened for specific binders, resulting in the isolation of a single clone secreting a chitosan-specific IgM, mAbG7. In ELISAs, the antibody could bind to chitosans of varying composition, but demonstrated the highest affinity for chitosans with lower degrees of acetylation (DA) and very poor binding to chitin. We tested the ability of the antibody to bind to chitosan in situ, using preparations of fungal cell walls. Immunofluorescence microscopy confirmed that the antibody bound strongly to the cell walls of fungi with high levels of chitosan, whereas poor staining was observed in those species with cell walls of predominantly chitin or cellulose. The potential use of this antibody for the detection of fungal contamination and the protection of plants against fungal pathogens is discussed.

• 농촌계획
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• 제20권1호
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• pp.127-134
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• 2014

This study, in order to complement instability of analysis result stemming from the choice between reference point and comparison point which is pointed out as the defect of shift-share analysis, conducted shift-share analysis using Gross Regional Domestic Product (GRDP) trend of Geumgang area, Chungcheongnam-do for the period from 2000 to 2011. As a result of the analysis, (1) industries that had both the positive Regional Share Effect (RSE) and Industrial Mixed Effect (IME) were service industries such as manufacturing industry, electricity gas, transportation industry, art, etc., which are positively influencing the regional industry. (2) industries that had both the negative RSE and IME were other service industries such as wholesale and retail businesses, lodging industry, food industry, real estate business and leasing service, business service industry, public administration, etc., which provide basic livelihood services for the residents. (3) industries that had the positive RSE and negative IME were agriculture, forestry and fishery industry, mining industry, construction industry, and educational service industry. (4) industries that had the negative RSE and positive IME were info-communications industry, financial and insurance businesses, health industry, etc.

• 대한의용생체공학회:의공학회지
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• 제23권3호
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• pp.227-233
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• 2002

이식형 인공중이는 음질과 주파수 특성이 우수하며 기존의 공기전도형 보청기가 가지는 고이득에서의 왜곡과 음향 피이드백에 의한 링잉 현상을 해소할 수 있어 차세대 보청기로 주목받고 있다 특히 두 개의 영구자석을 같은 극기리 접착한 후 코일내부에 위치시킨 타동 전자 트랜스듀서 방식의 이식형 인공중이는 외부의 자기장에 대해 영향을 받지 않으며 진동효율이 높고 자석과 코일의 간격조정이 필요 없는 동시에 주파수 응답특성이 우수하다. 본 연구에서는 이식형 인공중이에 사용하위해 개발된 타동 전자 트랜스듀서의 음향 모델을 구현한 후 정상인의 귀의 청각 모델에 적용시켜 트랜스듀서를 통하여 내이로 전달되는 신호의 주파수 특성을 해석하였다. 해석된 결과를 정상인의 귀의 주파수 특성과 비교함으로써 인공중이를 사용할 경우와 정상인의 귀와의 신호전달 특성 차이를 조사하였고 이를 통하여 정상인의 청각특성에 가까운 신호를 전달시킬 수 있는 인공중이의 설계가 가능하도록 하였다.

• 한국경영정보학회:학술대회논문집
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• 한국경영정보학회 2007년도 International Conference
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• pp.764-769
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• 2007

This paper proposes a new model to· evaluate the effectiveness of websites using balanced scorecard (BSC) and weighted formula based methods.fisrt, we Use BSC method to find out the cause-and-effect relationships between the measure and website activities, and our proposed model evaluates website performance from six perspectives: business value, operational excellence, customer value, website interface, management, maintenance, and learning and innovation. Next, we usedformula-based approach to identify what makes website performance low by developing the evaluation formula through investigating website users; finally, case studies of two famous websites are given to show how our method can be used Our evaluation model can not only evaluate website performance but also suggest how to improve performance.

• 한국멀티미디어학회논문지
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• 제21권1호
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• pp.18-25
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• 2018

In High Efficiency Video Coding (HEVC), integer motion estimation (IME) requires a large amount of computational complexity because HEVC adopts the high flexible and hierarchical coding structures. In order to reduce the computational complexity of IME, this paper proposes the search range reduction algorithm, which takes advantage of motion vectors similarity between different layers. It needs only a few modification for HEVC reference software. Based on the experimental results, the proposed algorithm reduces the processing time of IME by 28.1% on average, whereas its the $Bj{\emptyset}ntegaard$ delta bitrate (BD-BR) increase is 0.15% which is negligible.