• The Korea Journal of Herbology
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• v.26 no.3
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• pp.15-21
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• 2011

Objectives : The application of polymerase chain reaction (PCR) for the discrimination of the herbal medicine Leonuri Herba (Leonurus japonicus) was evaluated by the comparison of the DNA sequence with Lamiaceae herbal medicine. Method : Genetic analysis showed that phylogenetic tree and comparing sequences through the DNA analysis of rbcL (ribulose-1, 5-bisphosphatecarboxylase) region and trnL-F (tRNA-Leu, trnL-trnF intergeni cspacer, and tRNA-Phe) region of chloroplast DNA from six Lamiaceae sold in market. And we developed IMCF and IMCR primers in order to distinction Leonuri Herba in six Lamiaceae using rbcL and trnL-F sequences. Results : Genetic analysis showed that six Lamiaceae showed individual group on phylogenetic tree. PCR amplification product of Leonuri Herba and another five Lamiaceae were developed for amplification of a 281 bp sequence and the specific PCR amplification of a 460 bp sequence that was exclusive to Leonuri Herba was designed using IMCF and IMCR primers. Conclusion : PCR analysis based on the chloroplast DNA sequences allows the discrimination of Leonuri Herba-based medicine.

• Food Science and Biotechnology
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• v.18 no.1
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• pp.239-244
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• 2009

In the current study, inhibitory activity of 8 selected Korean edible plants of Lamiaceae family against $\alpha$-glucosidases, prepared from rat small intestine acetone powder was evaluated. Total flavonoids and oxygen radical absorbance capacity (ORAC) were also investigated. Methyl alcohol extracts of Scutellaria indica (SI) had the highest $\alpha$-glucosidase inhibitory activity relevant for potentially managing hyperglycemia, followed by Clinopodium gracile (CG) and Thymus quinquecostatus (TQ). These 3 species also showed significant antioxidant activity in ORAC system. The $\alpha$-glucosidase inhibitory activity of the extracts was compared to selected phenolics. Among the standard phenolics tested quercetin which was major flavonoid in the extracts had the highest $\alpha$-glucosidase inhibitory activity. CG, TQ, and SI which had high quercetin content and ORAC values also exhibited significant sucrase inhibitory activity. Results suggested that selected 3 Korean Lamiaceae species have the potential development of effective dietary strategy for postprandial hyperglycemia and oxidative stress-linked diabetes complications.

• Korean Journal of Plant Taxonomy
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• v.41 no.3
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• pp.249-252
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• 2011

Scutellaria tuberifera C. Y. Wu & C. Chen belonging to Lamiaceae, a species previously unrecorded for Korean flora, was collected streamside in the Andeok valley of Seogwipo-Si, on Jeju island. This species can be distinguished from others of Scutellaria from Korea by having rhizomes with leafless and branching stolons at the nodes, globose to ovoid tubers 5-7 mm in diameter at the terminal parts, and stems densely spreading pilose. Photos of the habit and illustration are provided.

• Korean Journal of Plant Taxonomy
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• v.49 no.2
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• pp.198-201
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• 2019

We report Scutellaria krasevii Kom. & I. Schischk. ex Juz. (subfamily Scutellarioideae, family Lamiaceae) as a new recorded species of Mongolia. This species is morphologically similar to S. galericulata but can be differentiated by the presence of comparatively thick and triangular-cordate leaves having a heteromerously deep-crenate margin, a densely reclinate pubescent stem, and a densely pubescent corolla. A taxonomic description, a key to the genus in Mongolia, habit photographs, and scanning electron photomicrographs of nutlets are provided for species identification. We also present a table for a comparison of the diagnostic characteristics with those of related species. This species grows along the banks of the Unit river, Khutag-Undur soum, Bulgan province, Mongolia, approximately 2,300 km far away from the type locality in Russia.

• Korean Journal of Plant Taxonomy
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• v.52 no.4
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• pp.269-274
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• 2022

Dracocephalum rupestre Hance is a perennial herb distributed across China, Mongolia, and Korea. This study reports the first complete chloroplast genome sequence of D. rupestre. The plastome is 151,230 bp long and exhibits a typical quadripartite structure comprising a large single-copy region of 82,536 bp, a small single-copy region of 17,408 bp, and a pair of identical inverted repeat regions of 25,643 bp each. It contains 130 genes, comprising 85 protein-coding genes, 37 tRNA genes, and eight rRNA genes. Phylogenetic analysis of D. rupestre and related species of Lamiaceae showed that the genus Dracocephalum is a monophyletic group, and D. rupestre is most closely related to D. psammophilum.

• Korean Journal of Plant Taxonomy
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• v.43 no.2
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• pp.99-102
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• 2013

The natural populations of Lycopus lucidus Turcz. ex Benth. var. hirtus Regel (Lamiaceae) were found in Gangwon province, Korea. This taxon was mainly distinguished from L. lucidus Turcz. ex Benth. var. lucidus by having multicellular hairs on the stem and leaves. However, the delimitation of this taxon from the typical plants of this variety (var. lucidus) was never assessed and the existence of this taxon was obscure in Korea. So, we provide a detailed morphological description of this taxon, as well as its geographical distribution and habitat.

• Korean Journal of Plant Taxonomy
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• v.40 no.4
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• pp.262-266
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• 2010

A new variety of Elsholtzia splendens (Lamiaceae) was found by the roadside of a mountain base at Jungmun-dong, Seogwipo-si, Jeju-do. The new taxon is termed Elsholtzia splendens var. fasciflora N.S. Lee, M.S. Chung & C.S. Lee, var. nov. The Korean name 'Da-bal-kkot-hyang-yu' was given. The morphological characters and illustrations of the species based on the holotype are provided together with a photograph of the habitat. It is distinctly distinguished from Elsholtzia splendens var. splendens by a few characteristics: leaves that area 2-4 cm long, leaves beneath the inflorescence, typically mostly 4; and inflorescence mosyly 2-4, fascicled, involucres oval.

• Korean Journal of Plant Taxonomy
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• v.47 no.2
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• pp.161-169
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• 2017

The genome size is one of the basic characters of an organism, and it is widely applied in various fields of biology, such as systematics, breeding biology, population biology, and evolutionary biology. This factor was recently highlighted in genome studies because choosing a representative of a plant group having the smallest genome size is important for the efficiency of a genome project. For the estimation of the genome size, flow cytometry has recently been highlighted because it is a convenient, fast, and reliable method. In this study, we report the genome sizes of 15 taxa of Lamiaceae from nine genera distributed in Korea using flow cytometry. Data pertaining to the genome size for all of our species have not been reported thus far, and the data from Agastache, Clinopodium, Elsholtzia, and Isodon are the first reported for each genus. The genome sizes of 15 genera and 39 species were reported to the Plant DNA C-values Database (http://data.kew.org/cvalues/). Scutellaria indica L. has a genome size of 0.37 pg (1C). This is the fourth smallest value among the 98 Lamiaceae taxa in the Angiosperm DNA C-value Database, indicating that this taxon can be used as a reference species in the genome studies in Lamiaceae as a native Korean species. The largest genome size observed in this study is in Phlomis umbrosa Turcz. (1C=2.60 pg), representing the possible polyploidy origin of this species in the family.

• Natural Product Sciences
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• v.6 no.2
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• pp.66-69
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• 2000

Salvia bucharica belonging to the family Lamiaceae (Labiatae), afforded a novel terpenoid (1) named as salvatrione. The structure of 1 was elucidated through extensive 2-D NMR experiments and the biogenetic pathway of 1 has also been proposed. On biogenetic grounds, 1 may be considered to be a pseudo-triterpenoid as it is derived from the coupling of mono/ diterpenic units and not from squalene.

• Korean Journal of Pharmacognosy
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• v.47 no.2
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• pp.192-196
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• 2016

The herb of Agastache rugosa (Lamiaceae) called Korean mint as a spice or Agastache Herba as a crude drug is known to contain highly fragrant volatile substances. This research aimed to establish the quantitative gas chromatography (GC) method on the essential oil of A. rugosa using the three standard compounds, estragole, methyleugenol, pulegone, and to find whether the essential oil has anti-Alzheimer's activity. The GC quantification method was established by determining the linearity of calibration curve ($R^2$), linear range, and both limit-of-detection (LOD) and limit-of-quantification (LOQ). The $IC_{50}$ of the essential oil on the activities of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) were determined to be $69.06{\pm}0.26$ and $76.71{\pm}0.58{\mu}g/ml$, respectively.