• 대한상한금궤의학회지
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• v.11 no.1
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• pp.1-9
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• 2019

Objective : The purpose of this study was to analyze the origin of Meretrix. Method : Bibliographies about Meretrix were examined focusing on the origin. Based on this analysis, the list and characteristics of the origin-mineral were presented. Results : Based on the Meretrix, the Korean and foreign literature were investigated to make a list, and the process of changing the origin was organized in chronological order. Based on these results, the shape of the currently cultivated or distributed drugs, the status of the distributed drugs and the status of the distributed products were summarized. In addition, the results of summarizing the adverse effects and sensitivities of the efficacy and prestige are as follows: 1. The origin of the Meretrix corresponded to the fall of the mollusks Merethrix metrix L. and Cyclina sinensis Gmelin, which are mollusks belonging to the reference family Veneridae. Their Herbal name is CONCHA CYCLINAE SEU MERETRICIS and they have therapeutic effects on cough, asthma, thirsty and chest heavies. 2. Munhap (文蛤) is a different name of GALLA CHINENSIS. It has therapeutic effects on various skin diseases. Conclusions : The Meretrix means two herbs. The first one is CONCHA CYCLINAE SEU MERETRICIS, the other is GALLA CHINENSIS. They should be used separately according to their clinical use.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.45 no.6
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• pp.600-605
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• 2012

In this study, we investigated the mechanism of inhibition of pathogenic bacteria by Pediococcus pentosaceus strain SH-10 isolated from hard Clam Meretrix meretrix sikhae. When P. pentosaceus SH-10 was co-cultured in MRS broth with pathogenic bacteria, including Bacillus cereus, Listeria monocytogenes, Salmonella choleraesuis and Staphyloccus aureus, no viable pathogenic cells were detected after 18 h of incubation. However, pediocin or a pediocin-like bacteriocin was not detected in cultures of P. pentosaceus SH-10 by the agar diffusion method. Organic acids were produced in MRS broth in proportion to the incubation time of P. pentosaceus SH-10. These results indicate that P. pentosaceus SH-10 inhibited the growth of pathogenic bacteria by lowering the pH of the growth medium through the production of organic acids, including sodium lactate, sodium acetate, and sodium citrate.

• Proceedings of the Malacological Society of Korea Conference
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• 1999.11a
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• pp.2-4
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• 1999

• Development and Reproduction
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• v.18 no.2
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• pp.89-98
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• 2014

The twenty-one individuals of Meretrix lusoria were secured from Gunsan, Shinan and Yeonggwang on the coast of the Yellow Sea and the southern sea in the Korean Peninsula, respectively. Amplification of a single COI fragment (720 bp) was imagined, and no apparent size differences were observed in amplified fragments between Meretrix lusoria and M. petechialis individuals. The size of the DNA fragments also varied excitedly, from 200 to 1,600 bp. The oligonucleotides primer BION-08 produced the least loci (a total of 17), with an average of 2.43 in the Gunsan population, in comparison to the other primers used. Remarkably, the primer BION-13 detected 42 shared loci by the three populations, major and/or minor fragments of sizes 200 bp and 400 bp, respectively, which were identical in all samples. The dendrogram gained by the seven oligonucleotides primers highlight three genetic clusters: cluster 1 (GUNSAN 01 ~ GUNSAN 07), cluster 2 (SHINAN 08 ~ SHINAN 14) and cluster 3 (YEONGGWANG 15 ~ YEONGGWANG 21). The longest genetic distance among the twenty-one Meretrix lusoria individuals that displayed significant molecular differences was between individuals GUNSAN no. 01 and SHINAN no. 14 (genetic distance = 0.574). Comparatively, individuals of SHINAN population were fairly closely related to that of YEONGGWANG population. In this study, PCR analysis has discovered significant genetic distances between two white clam population pairs (P<0.05).

• YAKHAK HOEJI
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• v.38 no.4
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• pp.394-400
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• 1994

As a previous step for the development of immunostimulating substance from marine natural products the two new lectins, MLA-II and MLA-III, have been isolated and purified from the hemolymph of Meretrix lusoria in addition to the previously reported MLA-I. The new lectins molecules were characterized as pure by electrophoretic studies.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.3
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• pp.528-532
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• 2011

This study was designed to investigate the collagen metabolism and tyrosinase activity of Meretrix extracts (ME). The effect of ME on type I procollagen production and collagenase activity in human normal fibroblasts HS68 after UVB (312 nm) irradiation was measured by ELISA method. The tyrosinase activity after treatment of ME was measured as well. Type I procollagen production was recovered by ME in UVB damaged HS68 cells. The increased collagenase activity after UVB damage was significantly recovered by ME. The tyrosinase activity and L-DOPA oxidation were significantly reduced as well. However, the effects on tyrosinase activity and L-DOPA oxidation were not powerful enough to be used as whitening agents. ME showed the anti-wrinkle effects and some whitening effects in vitro. These results suggest that ME may be a useful drug as an anti-wrinkle treatments.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.44 no.6
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• pp.605-611
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• 2011

This study examined the suitability of characteristics of potential strains of probiotic bacteria. Among 25 lactic acid bacteria isolated from Korean traditional fermented food, the Hard Clam Meretrix meretrix Shikhae, the SH-10 strain, which exhibited superior resistance to low pH and bile salts, was selected as a potential probiotic bacteria. By examining carbohydrate utilization, morphological properties, and the 16S rRNA gene sequence, the SH-10 strain was identified as Pediococcus pentosaceus (hereafter, P. pentosaceus SH-10). P. pentosaceus SH-10 was resistant to amikacin, cefotetan, ciprofloxacin, gentamicin, kanamycin, nalidixic acid, streptomycin, and vancomycin. Tests of antimicrobial activities against pathogens such as Bacillus cereus, Listeria monocytogenes, Salmonella choleraesuis, and Staphylococcus aureus, indicated that P. pentosaceus SH-10 inhibited the growth of pathogenic bacteria. These results suggest that P. pentosaceus SH-10 can be developed as a probiotic bacteria.

• The Korean Journal of Malacology
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• v.28 no.4
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• pp.377-384
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• 2012

The importance of biological resources has been gradually increasing, and mollusks have been utilized as main fishery resources in terrestrial ecosystems. But little is known about genomic and transcriptional analysis in mollusks. This is the first report on the transcriptomic profile of Meretrix lusoria. In this study, we constructed cDNA library and determined 542 of distinct EST sequences composed of 284 singletons and 95 contigs. At first, we identified 180 of EST sequences that have significant hits on protein sequences of the exclusive Mollusks database through BLASTX program and 343 of EST sequences that have significant hits on NCBI NR database. We also found that 211 of putative sequences through local BLAST (blastx, E < e-10) search against KOG database were classified into 16 functional categories. Some kinds of immune response related genes encoding allograft inflammatory factor 1 (AIF-1), B-cell translocation gene 1 (BTG1), C-type lectin A, thioester-containing protein and 26S proteasome regulatory complex were identified. To determine phylogenetic relationship, we identified partial sequences of four genes (COX1, COX2, 12S rRNA and NADH dehydrogenase) that significantly matched with the mitochondrial genomes of 3 species-Ml (Meretrix lusoria), Mp (Meretrix petechialis) and Mm (Meretrix meretrix). As a result, we found that there was a little bit of a difference between sequences of Korean isolates and other known isolates. This study will be useful to develop breeding technology and might also be helpful to establish a classification system.

• Korean Journal of Remote Sensing
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• v.37 no.5_1
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• pp.975-987
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• 2021

Potential habitat mapping of Meretrix lyrata which is found in large parts of South East Asian tidal flat was carried out to find out causes of collective death. Frequency Ratio (FR) method, one of geospatialstatistical method, was employed with some benthic environmental factors; Digital elevation model (DEM) made from Landsat imagery, slope, tidal channel distance, tidal channel density, sedimentary facesfrom WorldView-02 image. Field survey was carried out to measure elevation of each station and to collect surface sediment and benthos samples. Potential habitat maps of the all clams and the juvenile clams were made and accuracy of each map showed a good performance, 76.82 % and 69.51 %. Both adult and juvenile clams prefer sand dominant tidal flat. But suitable elevation of adult clams is ranged from -0.2 to 0.2 m, and that of juvenile clams is ranged from 0 to 0.3 m. Tidal channel didn't affect the habitat of juvenile clams, but it affected the adult clams. In the furtherstudy, comparison with case of Korean tidal flat will be carried out to improve a performance of the potential habitat map. Change in the benthic echo-system caused by climate change will be predictable through potential habitat mapping of macro benthos.

• The Korean Journal of Malacology
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• v.32 no.1
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• pp.25-30
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• 2016

Growth-line analysis was carried out on 80 hard clam (Meretrix petechialis) from the Neolithic Age Eurwang-dong Shell Midden, Incheon, Korea, to determine the seasonality of shellfish collection and site occupation. Growth increments and the marginal index (MI) of the specimens were examined. And then the marginal index was compared to the monthly MI of modern specimens under the assumption that the growth pattern was the same as it is today. MI of the archaeological specimens ranged from 0.12 to 1.55 and was divided into four categories: < 0.63, spring; 0.63-0.76, summer; 0.76-0.89, fall; $${\geq}_-0.89$$, winter collection. As a result, 57 specimens (71.25%) of 80 specimens represented spring, 8 (10.0%) summer, 3 (3.75%) fall and 12 (15.0%) winter collection. The result indicates that shellfish could be collected year-round at the site with an emphasis on spring. Based on the size distribution of shells and the content of the midden, however, it seems that the midden site was not occupied permanently throughout the year but was used repeatedly but temporally for shellfish gathering and processing.