• 동의생리병리학회지
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• 제17권3호
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• pp.842-844
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• 2003

Miller Fisher syndrome is characterized by ophthalmoplegia, ataxia and areflexia and develops after respiratory tract viral infection. Other events are GI tract infection, vaccination, digitalis intoxication, insect bite and delivery. Diagnosis of Miller Fisher syndrome can be made with clinical history taking, cardinal symptoms and normal findings of CT or MRI. We have experienced a case of Miller Fisher syndrome and treated with herbal medicine, eletro-acupuncture at paralytic external ophthalmic muscles. We enforced electro-acupuncture for 10 minutes daily. We used the PG-306 electro-acupuncture products(Suzuki Iryoki Co. Japan) and applied the low consequence wave of 1-8Hz. In 3 months, all the main symptoms disappered and the patient improved in health. Based on this experience, herbal medicine and eletro-acupuncture can be applied to the Miller Fisher syndrome.

• 대한한의학회지
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• 제20권4호
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• pp.98-105
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• 2000

Miller Fisher syndrome is characterized by acute external ophthalmoplegia, ataxia and areflexia in the abscence of significant motor or sensory deficit in the limbs and usually results in a complete recovery. Most cases have anteceding events like upper respiratory infection or other viral infections. Its accurate anatomic lesion sites and pathogenesis is still unknown. Recently we experienced a 47 year-old man who had a sudden onset of complete total ophthalmoplegia, ataxia, diplopia and whose condition was improved through Oriental medical treatment.

• 동의신경정신과학회지
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• 제20권3호
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• pp.229-236
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• 2009

Objectives : This study is designed investigate the effect of oriental medial therapy on a 63 year old female patient had Miller Fisher Syndrome with sleeplessness. Methods : We experienced a case of Miller Fisher Syndrome and treated with herbal medicine, eletro-acupuncture. The effects of treatment were measured by sleeping hour, taken measurements with a ruler(eyeball movement). Results : Whole condition (ophthalmoplegia, ataxia and so on) was improved and Oriental treatment had a good effect on sleeping hour. Conclusions : Oriental medical treatments were very effective for the patient had Miller Fisher Syndrome with sleeplessness.

• 척추신경추나의학회지
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• 제17권2호
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• pp.119-130
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• 2022

Objectives This study aimed to analyze the Korean medical treatment methods for Miller-Fisher syndrome from January 01, 2000 to December 31, 2021. Methods Six online databases (KISS, SCIENCEON, DBpia, RISS, KMBASE, and KoreaMed) were searched for clinical studies related to Miller-Fisher syndrome. Results Thirteen case reports were selected out of the 85 studies, and a total of 13 cases were analyzed. There were five kinds of Korean medicine treatment that were used in these studies. Acupuncture and herbal medicine were the most used interventions. Conclusions Korean medical treatment is found to be effective for Miller-Fisher syndrome. Although several limits remain, we expect that further research will be conducted to provide a better level of evidence.

• Journal of Acupuncture Research
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• 제29권6호
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• pp.105-110
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• 2012

Objectives : This study is designed to investigate the effect of oriental medical therapy on a 10 year old male patient had atypical Miller-Fisher syndrome with ophthalmoplegia and ptosis. Methods : We experienced a case of atypical Miller-Fisher syndrome and treated with acupuncture treatment, electro-acupuncture therapy, herbal medicine. The effect of treatment were evaluated with pictures of palpebra and eyeball movement. Results : After oriental medical treatment, ophthalmoplegia and ptosis was improved. Conclusion : Acupuncture, electro-acupuncture therapy and herbal medication is promising treatment for atypical Miller-Fisher syndrome with ophthalmoplegia and ptosis.

• 한방안이비인후피부과학회지
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• 제32권3호
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• pp.254-261
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• 2019

Objective : Miller-Fisher syndrome(MFS) is a type of acute inflammatory polyneuropathy, a disease characterized by abnormal muscle coordination, absence of tendon reflexes, and paralysis of the eye muscle. This study is to report a case of delayed facial palsy and dizziness in Miller-Fisher syndrome, treated with traditional Korean medicine. Methods : A 57-year-old male was diagnosed with Miller-Fisher syndrome accompanied by neurological symptoms such as right facial palsy and dizziness. He received traditional Korean medicine treatment such as acupuncture(including pharmacopuncture, needle embedding therapy, electroacupuncture) and herbal medicine for 17 days. Results : Each neurological symptoms were improved after traditional Korean medicine. In case of facial palsy, House Brackmann Grading System was reduced form grade 3 to grade 2, and Sunnybrook Scale was improved from 39 to 55. Also, other symptoms such as dizziness and headache was also improved. Conclusions : This case report suggests that traditional Korean medicine may have a role in treating neurological symptoms such as facial palsy and dizziness in patient diagnosed with Miller-Fisher syndrome.

• Annals of Clinical Neurophysiology
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• 제9권1호
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• pp.26-28
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• 2007

Miller Fisher syndrome (MFS) is a variant of Guillian-Barre syndrome (GBS) characterized by the triad of ophthalmoplegia, ataxia, and areflexia. Although recurrent GBS is a well known entity, the recurrence of MFS is extremely rare. Here we report an unusual case of recurrent MFS. Initially, the patient had presented with ophthalmoplegia, ataxia, areflexia, and tingling sensation of all extremities. After resolution of the first episode, the patient presented with atypical MFS characterized by ataxia, areflexia, and tingling sensation without ophthalmoplegia.

• Annals of Clinical Neurophysiology
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• 제8권1호
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• pp.71-73
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• 2006

Many neurologic signs are found in Miller Fisher syndrome (MFS) especially including pupillary abnormalities. But when internal ophthalmoparesis is first manifestation in MFS, diagnosis may be difficult in acute phase of illness. We report two cases of MFS presenting with internal ophthalmoplegia. Pupillary areflexia may be involved in acute phase of MFS. When acute bilateral internal ophthalmoparesis is encounted in clinical practice, initial manifestation of MFS should be included in differential diagnosis.

• Clinical and Experimental Pediatrics
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• 제57권12호
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• pp.542-545
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• 2014

Bickerstaff's brainstem encephalitis is characterized by ophthalmoplegia, ataxia, and disturbance of consciousness. It is similar to Miller Fisher syndrome, a variant of Guillain-Barre syndrome, in that they share features such as ophthalmoplegia and ataxia. The difference is that patients with Bickerstaff's brainstem encephalitis have impaired consciousness, whereas patients with Miller Fisher syndrome have alert consciousness and areflexia. Here, we report the case of a 3-year-old child who was diagnosed with Bickerstaff's brainstem encephalitis presenting typical clinical features and interesting radiological findings. The patient showed ophthalmoplegia, ataxia, and subsequent stuporous mentality. Brain magnetic resonance imaging revealed high signal intensity in the pons and cerebellum around the 4th ventricle on a T2-weighted image. He was successfully treated with intravenous immunoglobulin. Differentiation of Bickerstaff's brainstem encephalitis and Miller Fisher syndrome is often difficult because they possess many overlapping features. Brain magnetic resonance imaging may be helpful in diagnosing Bickerstaff's brainstem encephalitis, especially when lesions are definitely found.

• 한방안이비인후피부과학회지
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• 제33권2호
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• pp.130-139
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• 2020

Objectives : The aim of this study is to report the effect of Korean Medicine Treatment for patient with ophthalmoplegia in Miller-Fisher Syndrome. Methods : A patient with ophthalmoplegia treated with herbal medicine, cupping therapy and acupuncture(including pharmacopuncture, electroacupuncture). We used photographs of eye movement to evaluate the changes in symptoms, Scott and Kraft score of left eye, visual field test for measuring peripheral visual field, subjective symptom, and VAS for headache, subjective symptom. Results : After treatment, Scott and Kraft score increase from -4 to -2. Visual field of left side improved from 45° to 80°. Also, other symptoms such as diploma, dizziness, headache, gait disturbance was also improved. There are no adverse effects and no relapse of ophthalmoplegia after 20 days of discharge. Conclusions : This case report suggests that Korean Medicine Treatment can be effective for patient with ophthalmoplegia in Miller-Fisher Syndrome.