• 한방안이비인후피부과학회지
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• 제21권3호
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• pp.10-19
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• 2008

Objective : To investigate the effects of Radix Ophiopogon japonieus on atopic dermatitis, I prepared DNCB(2,4-dinitrochlorobenzen) induced atopic dermatitis NC/Nga mice and observed the mice by four ways; eye observation, the number of skin behavior times, histological changes of skin and cytokine(Total IgE, IL-4, $IFN-{\gamma}$). Methods : After prepare Radix Ophiopogon japonicus extract, DNCB induced atopic dermatitis NC/Nga mice were divided into three groups. The first is Control group which was intact group. The second is Medication group which was orally medicated Radix Ophiopogon japonicus extract one time a day for consecutive 5 days. The third group is Application group which was applied Radix Ophiopogon japonicus extract externally one time a day for consecutive 5 days. After that, the effect of Radix Ophiopogon japonicus on atopic dermatitis was observed. Statistical analysis was performed by using Kmskal-Wallis test and statistical significance was set at less than 5%. Results : 1. Radix Ophiopogon japonicus showed some in both Medication group and Application At observation of skin morphologic change, effects to prevent erythema reaction on skin group. 2. At the number of scratching behavior times, Radix Ophiopogon japonicus showed an effect to decrease scratching behavior times, but there was no statistical significance among three groups. 3. At skin tissue H-E stain, Radix Ophiopogon japonicus showed an effect to prevent skin epidermal tissue damages and also showed that it could keep the skin healthy in both Medication group and Application group. Especially in Application group, the skin of mouse showed almost normal recovery. 4. At cytokines, there was no statistical significance among three groups in IgE and IL-4. But Radix Ophiopogon japonicus showed an significant effect to suppress $IFN-{\gamma}$ in both Medication group and Application group. There was no significant difference between two groups. Conclusion : Radix Ophiopogon japonicus has some effects on atopic dermatitis in both internal medication and external application.

• 한국작물학회지
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• 제47권3호
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• pp.236-239
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• 2002

한국산 맥문동과 중국산 소엽맥문동의 성분패턴비교에서 HPLC 분석 결과, 중국산 소엽맥문동(Ophiopogon japonicus)은 RT. 21.2분의 peak는 표준품과 대조결과 spicatoside B인 것으로 확인되었다 반면에 국산 맥문동(Liriope platyphylla)은 spicatoside A와 spicatoside B가 표준품 대조 결과 RT. 6.8분과 21.2분대에서 확인되었다. 따라서 건조된 상태에서 혼용되어 사용하고 있는 한국산 맥문동과 중국산 소엽맥문동은 HPLC 성분패턴상으로 감별이 가능하게 되었다.

• 생약학회지
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• 제39권2호
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• pp.75-79
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• 2008

Nerve growth factor (NGF) is a protein plays a major role in the development and maintenance of central and peripheral nervous system. Recent data suggest that reduced availability of NGF may play a significant role in the pathogenesis of diabetic $polyneuropathy.^{1)}$ In our previous study, steroidal saponin from Liriope platyphylla showed neurotrophic effect by stimulation of NGF synthesis and activation of tyrosine kinase $signaling.^{2)}$ In this study, we examined the neurotrophic effect of Liriope platyphylla (LP); which was from Mylyang(MYL) and Cheongyang(CHE), and Ophiopogon japonicus (CHI) on in vitro and in vivo model for the comparison of their NGF induction. We quantitatively analyzed spicatoside A in the LP and CHI by HPLC. And we investigated the correlation between the contents of spicatoside A and NGF induction efficacy on PC 12 cells and mouse serum. These results suggest that spicatoside A may enhance NGF induction in animal model.

• Archives of Pharmacal Research
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• 제28권11호
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• pp.1236-1238
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• 2005

A new phenolic glycoside, ophiopojaponin D (1), together with two known compounds, was isolated from the tubers of a famous traditional Chinese herb-Ophiopogon japonicus Ker-Gawl. The spectroscopic and chemical data revealed their structures to be 3-tetradecyloxy-4­hydroxy-allylbenzene-4-O-$\alpha$-L-rhamnopyranosyl (1$\rightarrow$6)-$\beta$-D-glucopyranoside (1), 3, 4-dihy-droxy-allylbenzene-4-O-$\alpha$-L-rhamnopyranosyl (1$\rightarrow$6)-$\beta$-D-glucopyranoside (2) and L-pyro­glutamic acid (3).

• 한국동물학회:학술대회논문집
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• 한국동물학회 2000년도 한국생물과학협회 학술발표대회
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• pp.162.2-162
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• 2000

• 아시안잔디학회지
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• 제7권1호
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• pp.19-30
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• 1993

Experiments were conducted to investigate propagation, shade tolerance, cold resistance and growth rate of evergreen ground cover plants ; Vinca minor K , Ajuga reptans L., Ophiopogon japonicus ker. f nanus hort , and Hedera helix.. The results were as follows : 1.It is convenient to use the growing case for rice seed to grow and transplant Vinca minor seed-ling. The most proper density of transplanting Vinea was 180 plants per 1m$^2$. At the end of growing season, the coverage came up to 90% The rooting ability of Hedera helix was best to cut from April to May (temperature 15~23˚C). The seedling length of Parthenocissus quinguefohlia were irregular and ranged from 5 cm of 200cm. 2. Ajuga reptans L., Ophiopogon j. and Vinca minor L. grew better under 50% light intensity than full sunlight. Particularly, under full sunlight and aestival high temperature, there were a few withering plants in Ajuga reptans L. , and V Vilica minor L. 3. Of Vinca minor K., Ajuga reptans L. , Ophiopogon japonicus ker. f. nanus hort. and Hedera helix. acclimatized in open field, where temperature was from -7~8˚C. There were few plants had damage in low temperature incubator to -16˚C after field acclimatization. 4.Tendrils of Parthenocissus quinguefolia strongly clung to the wire netting stone fence but intruded into the gap and cranny of the precast concrete fence and so clung to, so that it needed to install the bending net on the precast concrete fence.

• 한국조경학회지
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• 제45권2호
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• pp.68-75
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• 2017

정원소재로서 수요가 늘어날 것으로 예상되는 애기소엽맥문동(Ophiopogon japonicus 'Nanus')을 대상으로 18개월(2015년 5월~2016년 10월)간 차광생육실험을 실시해 내음성 범위와 피복정도를 알아보았다. 전남 장흥군 노지에 3년간 재배된 애기소엽맥문동을 공시재료로 이용했다. 전남 나주시의 실험장에서 식재상자($70cm{\times}70cm{\times}24cm$)에 애기소엽맥문동을 심고 차광막을 덮어 자연광을 차단했는데 차광처리 수준은 무차광(0%), 55%, 75%이었다. 차광처리구별 생장량(엽장, 엽수, 생중량 건중량)과 지표면 피복률을 조사했다. 애기소엽맥문동의 엽장 엽수는 무차광(0%)이 다른 처리구보다 통계적으로 높았다. 생중량 건중량은 무차광(0%) 차광처리 55%가 차광처리 75%보다 유의적으로 많았다. 애기소엽맥문동이 정상적으로 생육가능한 내음성 범위는 차광률 0~50%정도며, 50%이상의 자연광이 차단되면 생장량이 감소하는 것으로 판단된다. 차광처리구별 피복률은 통계적 차이를 보이지 않았다. 애기소엽맥문동을 $1m^2$당 220분얼을 심었는데 18개월 후에는 지표면 80%까지 덮었다. 애기소엽맥문동은 비옥한 토양에서 생육이 적합해 조기 피복을 위해선 충분한 질소비료 시비가 필요하다. 본 실험장에서 애기소엽맥문동은 동해를 입지 않아 온대 남부지역까지 식재 가능할 것으로 보인다.

• 한국조경학회지
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• 제40권4호
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• pp.127-134
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• 2012

이 연구는 저관리 경량형 옥상녹화시스템을 위한 내한성 식물 선발을 목적으로 6종 식물을 대상으로 저온 처리시간과 온도에 따라 전해질 용출 평가와 재생 검사를 연구하였다. Logistic 비선형 회귀분석을 이용하여 전해질 용출 평가를 통하여 치사 온도는 $-16.1{\sim}-24.4^{\circ}C$ 범위로 예측되었으며, 저온에 대한 저항성은 Sedum reflexum > S. spurium > Ophiopogon japonicus > S. album > S. takevimense > Dianthus chinensis의 순으로 나타났다. 2012년 2월 최저 온도인 $-13.4^{\circ}C$에 모든 식물의 전해질 용출은 50% 이하로 나타났으며, 겨울철 최적기온 $-13.5^{\circ}C$ 이상의 지역에서 식물들을 옥상에서 안정적으로 생육될 수 있을 것으로 예측되었다.

• 생약학회지
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• 제34권1호통권132호
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• pp.6-9
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• 2003

‘Maig Moon Dong(麥問冬)’ is one of the chinese crude drugs used mainly to cure a cough and sputum, etc. With regard to the botanical origin of ‘Maig Moon Dong’, it has been considered to be Liriope species of Liliaceae, but there has not been studied pharmacognostically. To clarify the botanical origin of Maig Moon Dong, we studied on the anatomical characteristics of Liriope and Ophiopogon species growing wild in Korea i.e. L. platyphylla, L. spicata, O. jaburan, O. japonicus and Maig Moon Dong from Korea. As a result, the botanical origin of Maig Moon Dong from Korea was proved as Liriope platyphylla and L. spicata.

• Natural Product Sciences
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• 제7권2호
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• pp.33-37
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• 2001

Methanol extracts of eighty Chinese medicinal plants were investigated for platelet-activating factor (PAF) receptor binding inhibitory activity using rabbit platelet. Extracts of Cratoxylon ligustrinum, Kalimeris indica, Euonymus japonica, Ophiopogon japonicus, Gleditsia sinensis, Clausena lansium, Agave sisalana were found to exhibit significant inhibitory effects. Chloroform partition of the Methanol extract of Kalimeris indica was further fractionated by column chromatography to afford one strong active subfraction with 93.6% inhibition at a concentration of $100{\mu}g/ml$.