• Title/Summary/Keyword: Physiological functional evaluation

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Development of Drink from Composition with Medicinal Plants and Evaluation of its Physiological Function in Aorta Relaxation (한약재를 이용한 음료의 개발 및 혈관개선에 미치는 기능성 평가)

  • Han Jong Hyun;Song You Jin;Park Sung Hye
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.4
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    • pp.1078-1082
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    • 2004
  • The purpose of this study was to investigate the possibility of medicinal plants application as an edible functional food resources. We carried out to develop a traditional functional beverage by using hot-water extraction of 4 medicinal plants(Polygonatun sibiricum, Ophiopogonis radix, Lycii fructus, Schizandriae fructus) and we examined the effects of drink on physiological function in aorta relaxation. Thus, the effect of developed beverage on phenylephrine induced contraction of isolated rat thoracic aorta. Contractile force was measured with force displacement transducer under 1.5g loading tension. Brix, pH and titratable acidity of developed drink were 9.5%, 3.3 and 0.22%. The approximate nutritional composition of beverage was carbohydrate, 5.98%, crude protein, 0.70%, crude fat, 0.20% and crude ash, 0.20%. Developed beverage contained K(4.00 ㎎%), Na(3.68 ㎎%), Ca(2.54 ㎎%), Mg(1.60 ㎎%) and Fe(0.29㎎%). The contraction forces by injection of phenylephrine in isolated thoracic aorta were significantly low in each experimental groups compared with control groups, These results that developed drink with medicinal plants can be used as a functional material to decrease aorta contraction.

Analysis of quercetin in extract of Hovenia dulcis Thunb (헛개나무과병추출물 중 퀘르세틴 분석)

  • Hu, SooJung;Oh, Jae-Myoung;Oh, Hyun-Suk;Moon, Myung-Hee;Bae, Yun-Young;Lee, Sung-Hye;Kim, Ji-An;Koo, Yong-Eui
    • Analytical Science and Technology
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    • v.29 no.6
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    • pp.255-260
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    • 2016
  • Based on the Korean Health Functional Food Act, health functional foods are dietary supplements containing nutrients or other substances that have nutritional or physiological effects. Since generic health functional food items have been expanded, this project was performed to develop a standardized analytical method of examining such sale items. The method exhibited high linearity in the quercetin calibration curve ($R^2$ > 0.999) over concentrations of $0-40{\mu}g/mL$. The limits of detection and quantitation for quercetin were $0.12{\mu}g/mL$ and $0.36{\mu}g/mL$, respectively, while quercetin recovery was 97.1-105.4 % with standard deviations of 1.15-3.11 %. To verify the accuracy of the analytical methods, the labeled amounts of purchased health functional foods were monitored. The recovery rate for multiple quercetin concentrations ranged from 82.5-105.1 % of the labeled amounts. Thus, the new method was suitable for all cases.

Nutritional Contents of Beverage from Lotus Root and Evaluation of its Physiological Function in Aorta Relation (연근음료의 영양학적 특징 및 흰쥐의 혈관개선에 미치는 효과)

  • Ham, Tae-Sick;Han, Jong-Hyun;Park, Sung-Hye
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.2
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    • pp.490-494
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    • 2005
  • The purpose of this was investigate the possibility of medicinal plants application as an edible functional food resources. We arried out to develop a beverage by using Nelumbo nucifera and we examined the nutritional characterics. Also we examined the effects of drink on physiological function in aorta relation. Thus, the effect of developed beverage on phenylephrine induced contraction of isolated rat thoracic aorta. Contractile force was measured with force displacement thansducer under 1.5g loading tension. Brix, pH and titratable acidity of developed drink were 12.25%, 4.5 and 0.092%. The approximate nutritional composition of beverage was carbohydrate, 9.40%, crude protein, 0.30%, crude fat, 0.25% and ash, 0.15%. Also insoluble fiber and soluble fiber were 1.30%, 0.80%. Developed beverage contained Na(11.45 mg%), K(6.87 mg%), Ca(2.53 mg%). The contraction forces by injection of phenylephrine in isolated thoracic aorta were significantly law in each beverage treatment groups compared with control group. These results that developed drink with medicinal plants can be used as a functional material to decrease aorta contraction.

Development of Drink from Composition with Medicinal Plants and Evaluation of Its Physiological Function (생약재를 이용한 음료의 개발 및 기능성 평가)

  • 박성혜;황호선;한종현
    • Journal of Nutrition and Health
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    • v.37 no.5
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    • pp.364-372
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    • 2004
  • The purpose of this study was to investigate the possibility of medicinal plants application as an edible functional food resource. We carried out to develop a traditional functional beverage by using hot-water extraction of 4 medicinal plants (Polygonatun sibiricum, Ophiopogonis radix, Lycii fructus, Schizandriae frutcus) and we examined the effects of drink on physiological response during exercise and recovery phase. The subjects were male baseball players, and exercise protocol was performed with 45 minutes treadmill running and 85% VO$_2$ max intensity. Brix, pH and titratable acidity of developed drink were 9.5%, 3.3 and 0.22%. The approximate nutritional composition of beverage was carbohydrate, 5.98%, total dietary fiber, 0.42%, crude protein, 0.70%, crude fat, 0.20% and crude ash, 0.20%. Developed. traditional functional beverage contained K (4.00 mg%), Na (3.68mg%), Ca (2.54mg%), Mg (1.60mg%) and Fe (0.29mg%). Developed beverage drinking group showed a lowest heart rate during exercise and recovery phase than the other two group (water group and ion beverage group). In the change of blood lactate concentration, developed beverage intake group showed a significant lowest values during exercise and recovery phase. And blood hematocrit values and osmolarity were lowest in the developed beverage intake group. In these results, exercise performance capacity was expected to improve most highly with the developed drink from composition with medicinal plants. Also developed beverage was effective in recovery of exercise-induced fatigue. Thus developed drink with medicinal plants can be used as a functional material improving decrease fatigue effects in beverage industry.

Preliminary Study to Develop the Instrument of Korean Medical Pattern Identification and Functional Evaluation for Five Organ (한의 오장변증진단평가 도구 개발을 위한 기초 연구)

  • Jang, Eunsu;Yun, Yong Gi;Yoo, Ho Rhyong;Yoo, Jeong Eun;Kim, In Chang;Park, Ji-Yeun;Jung, In-Chul
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.31 no.2
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    • pp.126-137
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    • 2017
  • This study was aimed to develop the instrument of Korean medical pattern Identification and Functional Evaluation for Five Organ. This study followed seven steps, consisted of first composition of research members, second set-up of the aim, third review for advanced research, fourth finding an important index, fifth puting on the weight for index, sixth advice from linguist and last development of draft of questionnaire. Twenty two in and out researchers joined and put the weight on each question. We developed a draft version of questionnaire of Korean medical pattern identification and functional evaluation for five organ. Most questions between pattern identification and functional evaluation of five organ have similar weight, but several ones have difference in order. Generally, specific symptom represented specific location or related with pain have relatively higher weight on pattern identification, and weakness question gained weight on functional evaluation. We develop the questionnaire of Korean medical pattern identification and functional evaluation for five organ. Following study, which will evaluate the reliability and validity, is needed.

Basic Physiological Research on the Wing Flapping of the Sweet Potato Hawkmoth Using Multimedia

  • Nakajima, Isao;Yagi, Yukako
    • Journal of Multimedia Information System
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    • v.7 no.2
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    • pp.189-196
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    • 2020
  • We have developed a device for recording biological data by inserting three electrodes and a needle with an angular velocity sensor into the moth for the purpose of measuring the electromyogram of the flapping and the corresponding lift force. With this measurement, it is possible to evaluate the moth-physiological function of moths, and the amount of pesticides that insects are exposed to (currently LD50-based standards), especially the amount of chronic low-concentration exposure, can be reduced the dose. We measured and recorded 2-channel electromyography (EMG) and angular velocity corresponding to pitch angle (pitch-like angle) associated with wing flapping for 100 sweet potato hawkmoths (50 females and 50 males) with the animals suspended and constrained in air. Overall, the angular velocity and amplitude of EMG signals demonstrated high correlation, with a correlation coefficient of R = 0.792. In contrast, the results of analysis performed on the peak-to-peak (PP) EMG intervals, which correspond to the RR intervals of ECG signals, indicated a correlation between ΔF fluctuation and angular velocity of R = 0.379. Thus, the accuracy of the regression curve was relatively poor. Using a DC amplification circuit without capacitive coupling as the EMG amplification circuit, we confirmed that the baseline changes at the gear change point of wing flapping. The following formula gives the lift provided by the wing: angular velocity × thoracic weight - air resistance - (eddy resistance due to turbulence). In future studies, we plan to attach a micro radio transmitter to the moths to gather data on potential energy, kinetic energy, and displacement during free flight for analysis. Such physiological functional evaluations of moths may alleviate damage to insect health due to repeated exposure to multiple agrochemicals and may lead to significant changes in the toxicity standards, which are currently based on LD50 values.

Physiological Responses of Wearing Protective Welding Clothing Considering the Work Environment of the Shipbuilding Industry (조선업 작업환경을 고려한 용접 보호복 착의시 인체생리반응)

  • Kim, Min-Young;Bae, Hyun-Sook
    • Journal of the Korean Society of Clothing and Textiles
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    • v.37 no.2
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    • pp.235-245
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    • 2013
  • Physiological responses and subjective sensations were evaluated for wearing protective welding clothing in consideration of the work environment for the shipbuilding industry. Experimental clothing was made of oxidant carbon nonwoven fabric (SW2) and oxidant carbon/p-aramid blended fabric (SW4). The values of all items in physiological responses were higher upon wearing oxidant carbon experimental clothing versus wearing oxidant carbon/p-aramid experimental clothing (p<.001). The results of the wearing evaluation in the welding work on-site showed that existing leather protective clothing had a very low satisfaction of permeability, weight sensation and wearing sensation. For the wearing sensation of experimental clothing with SW2, permeability and durability were poor and the pressure and weight sensation satisfaction was very high. In case of SW4, the satisfaction was very high in functional movement, pressure, weight sensation and management aspects; subsequently, the overall wearing satisfaction was very good.

The Model for Evaluation on Blood Flow of Functional Food in Human Intervention Study (인체에서 식품의 혈행 개선 효능 평가 모델)

  • Lim, Yeni;Kwon, Oran;Kim, Ji Yeon
    • Journal of Lipid and Atherosclerosis
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    • v.7 no.2
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    • pp.88-97
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    • 2018
  • The prevalence of atherothrombotic disease continues to rise, presenting an increasing number of challenges to modern society and creating interest in functional foods. Platelet activation, adhesion, and aggregation at vascular endothelial disruption sites are key events in atherothrombotic disease. Physiological challenges such as hyperlipidemia, obesity, and cigarette smoking are associated with vascular changes underlying platelet aggregation and inflammatory processes. However, it is difficult to determine the beneficial response of functional foods in healthy subjects. To address this problem, challenge models and high-risk models related to smokers, obesity, and dyslipidemia are proposed as sensitive measures to evaluate the effects of functional foods in healthy subjects. In this review, we construct a model to evaluate the effects of functional food such as natural products on blood flow based on a human intervention study.

Effect of the Shoulder Pad on Arm Movement -In the Area of Functionality and Sensory (팔동작에 미치는 어깨패드의 영향에 관하여 -심미성과 기능성을 중심으로-)

  • 이은정
    • The Research Journal of the Costume Culture
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    • v.6 no.2
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    • pp.66-76
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    • 1998
  • In order to investigate the effect of shoulder pad affecting the arm movement, eleven women volunteers of standard body whose age is from eighteen to twenty-four(x±1σ) were chosen and this experiment had done according to front-vertical motion, side-vertical motion and horizontal motion of upper limps for tow different materials of shoulder pad(sponge, non-woven) and four different thickness of shoulder pad(0.6cm, 0.8cm, 1.2cm). On the base of this, this study, when putting on shoulder pad, try to find the reform method of shoulder part pattern. The results are as follows. 1. When puting on shoulder pad to blouse pattern to rise shoulder pad for rate of two-third per thickness is seemingly the best for sensory evaluation. So, when putting on shoulder pad, we understand that in order to improve sensory evaluation. So, when putting on shoulder pad, we understand that in order to improve sensory evaluation of clothes, when that, rising shoulder pad for ate of two-third per thickness is the best. 2. From the results of measure of functional volume and physiological value for functionality evaluation according to thickness and material, motion of shoulder pad, 1.2 cm thickness and non-woven material is evaluated the worst for functionality. 3. From the results of sensory evaluation and functionality evaluation of material of shoulder pad, sponge material is superior for functionality but not for sensory evaluation, non-woven material is superior for sensory evaluation non-woven material is superior for sensory evaluation but not for functionality. So, think that it had better use sponge material for functional clothes, non-woven material for aesthetical clothes. 4. From the results of functionality of clothes, when putting on shoulder pad, the worst discomfortable parts are the armpit part and the shawl part, functionality of these part shoulder be reformed.

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Generalized Analysis on Validity of Sasang Type Diagnosis (사상체질 진단검사 타당성 분석지표의 일반화 연구)

  • Hwang, Sang-Moon;Park, So-Jung;Gang, Ki-Rim;Kwon, Young-Kyu;Chae, Han
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.5
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    • pp.950-957
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    • 2009
  • The purpose of this study was to develop generalized validity evaluation indexes for the Sasang type diagnostic test. As a generalized evaluation index for Sasang type diagnostic test, Generalized Squared Correlation (GC2), Mutual Information (I) and Mutual Information Coefficient (IC) as overall validity index, and Correlation Coefficient (C) and Mutual Information Contribution (ID) as type-specific validity index were suggested and the practicability of these indexes was assessed along with Percentage Correctly Predicted (PCP), adjusted PCP, type-specific sensitivity and type-specific specificity which was proposed previously. The usefulness of the nine validity indexes was examined using previously reported data and three mock Sasang type diagnosis results. We demonstrated here that the PCP is not adequate for the analysis of validity. We also showed that our validity index is recommendable for the comparison and improvement of Sasang type diagnosis. The generalized validity analysis of Sasang type diagnosis can provide a guideline for the development of new Sasang type diagnosis or pattern identification. The working sheet for calculating validity indexes can be acquired at http://www.sasangtypology.org/validity.