• 동의생리병리학회지
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• 제34권4호
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• pp.159-169
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• 2020

Shanghanlun (Treatise on Cold Damage Diseases) is the oldest document in the literature on clinical records of Traditional Asian medicine (TAM), on which TAM theories about symptoms-herbs relationships are based. In this study, we aim to quantitatively explore the relationships between symptoms and herbs in Shanghanlun. The text in Shanghanlun was converted into structured data. Using the structured data, Term Frequency - Inverse Document Frequency (TF-IDF) scores of symptoms and herbs were calculated from each chapter to derive the major symptoms and herbs in each chapter. To understand the structure of the entire document, principal component analysis (PCA) was performed for the 6-dimensional chapter space. Bipartite network analysis was conducted focusing on Jaccard scores between symptoms and herbs and eigenvector centralities of nodes. TF-IDF scores showed the characteristics of each chapter through major symptoms and herbs. Principal components drawn by PCA suggested the entire structure of Shanghanlun. The network analysis revealed a 'multi herbs - multi symptoms' relationship. Common symptoms and herbs were drawn from high eigenvector centralities of their nodes, while specific symptoms and herbs were drawn from low centralities. Symptoms expected to be treated by herbs were derived, respectively. Using measurable metrics, we conducted a computational study on patterns of Shanghanlun. Quantitative researches on TAM theories will contribute to improving the clarity of TAM theories.

• 대한한의학회지
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• 제32권1호
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• pp.56-66
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• 2011

Background: This was a study to analyze Sanghanron through network theory, as the first attempt to construct network models for systems biomedicine in traditional Korean medicine. For this purpose, we investigated the network structure with priority given to two-node connections between symptoms and herbs of Taeyangbyung compilation in Sanghanron. Purpose: We had three goals in carrying out this study. First, to establish the minimum clinical grouping data sets for symptoms and herbs of Taeyangbyung compilation in Sanghanron. Second, to make index files for the obtained data sets. Third, to generate a network structure for systems biomedicine in this part, and analyze its relationship. Methods: Using MS office Excel and Netminer software, we constructed the minimum clinical grouping data sets and the network for systems biomedicine about symptoms and herbs of Taeyangbyung compilation in Sanghanron, and analyzed its relationship. Results: We established the minimum clinical grouping data sets for symptoms and herbs of Taeyangbyung compilation in Sanghanron, using MS Excel. We constructed a network to structurize our database through two-node connections of Netminer program, and analyzed its relationships. Conclusions: Further research on network model for systems biomedicine between symptoms and herbs for three Yang and three Um(Taeyang, Soyang, Yangmyung, Taeum, Soum, Gualum) disease compilation is necessary.

• 한국의사학회지
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• 제31권1호
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• pp.43-55
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• 2018

This is a review of Juchon (舟村) Sinman's (申曼) book "Juchonsinbang (舟村新方)", describing generations of clinical experience in pediatric practice. Written during King Sukjong era in the middle of the Joseon Dynasty, JuchonSinman used symptoms and general disease terminology, including prescription and treatments employed over generations, so the public could easily utilize the information. "Juchonsinbang (舟村新方)" "pediatric (小兒編)" is characterized by a symptom differentiation method of prescribing herbs which allowed the reader to add or subtract various substances according to symptoms based on Tongchibang (通治方). "Juchonsinbang" includes unique prescriptions and new ways to distinguish acute infantile convulsion (急驚風) according to the cause of fright. Although these prescriptions were not completely new, they present an aspect of an empirical book including JuchonSinman's clinical experience based on existing medical theories. "Juchonsinbang" has a medico-historical value in that it was cited in many medical books such a "Danbangsinpyun (單方新編)", "Sujinggyunghumsinbang (袖珍經驗神方)", and "Hanbang medical pediatric book (漢方醫學小兒全科)" in 1910-30.