• Title/Summary/Keyword: Thromboangiitis Obliterans

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A Systematic Review of Acupuncture Treatment for Thromboangiitis Obliterans (폐색성 혈전 혈관염의 침 치료에 대한 체계적 문헌고찰)

  • Choi, Ji Min;Jeon, Seok Hee;Lim, Yong Ha;Jung, Min Jae;Kim, Seon Jong
    • Journal of Korean Medicine Rehabilitation
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    • v.32 no.1
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    • pp.37-49
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    • 2022
  • Objectives The purpose of this study is to present evidence by analyzing the research trends in acupuncture treatment in the last 10 years for thromboangiitis obliterans. Methods Randomized controlled trials about acupuncture on thromboangiitis obliterans were searched China National Knowledge Infrastructure (CNKI), PubMed, EMBASE, Cochrane Library, Oriental Medicine Advanced Searching Integrated System (OASIS), ScienceON, Koreanstudies Information Service System (KISS) and Research Information Sharing Service (RISS) from January 1, 2011 to November 13, 2021. Only randomized controlled trials were selected and we assessed the risk of bias (RoB) according to the revised Cochrane RoB2 criteria. Results A total of 5 randomized controlled trials (RCTs) were selected in this review and all were conducted in China. A total of 326 participants were in 5 RCTs. SP10, ST36, GB34 was the most commonly used treatment point. There were four types of acupuncture used: manual acupuncture, embedding acupuncture, pharmacopuncture, electroacupuncture. The most commonly used indicator for evaluation was the total efficacy rate, and all five studies were significantly higher. Conclusions All selected studies showed the group treated with acupuncture treatments on thromboangiitis obliterans were statistically more effective than the control group. However, the number of studies is too small and the interpretation of the results is limited due to the inclusion of subjective evaluation. So more objective and systematic studies should be conducted continuously.

Literature Review on Syndrome Differentiation and Herbal Medicine of Thromboangiitis Obliterans (폐색성 혈전혈관염의 변증과 처방에 관한 문헌적 고찰)

  • Jeong, Jong Jin;Sun, Seung Ho;Lee, Yong Hyun;Go, Ho Yeon;Jung, Ki Yong;Song, Yun Kyung;Kim, Tae Hoon;Hong, Sung In;Choi, You Kyung;Go, Seong Gyu;Lim, Eun Mee;Park, Jong Hyeong;Jeon, Chan Yong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.29 no.2
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    • pp.143-151
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    • 2015
  • This study was aimed at investigating the syndrome differentiation and herbal medicine of Thromboangiitis Obliterans by reviewing Chinese traditional medicine's journals. The journal search was carried out using China National Knowledge Infrastructure(CNKI) and PubMed from September 2009 to August 2014. Searching key words were the various combination of "Thromboangiitis Obliterans", "traditional chinese medicine", "syndrome differentiation", "herbal medicine". The final selection of 33 studies were selected and summarized by researchers. The syndrome differentiation was classified as yang deficiency, cold syncope and blood stasis. The most frequently herbs were blood-activating and stasis-resolving medicinals.

Early Diagnosis and Intervention Are Needed for a Reasonable Prognosis of Thromboangiitis Obliterans

  • Miju Bae;Sung Woon Chung;Jonggeun Lee;Eunji Kim;Gayeon Kang;Moran Jin
    • Journal of Chest Surgery
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    • v.56 no.5
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    • pp.328-335
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    • 2023
  • Background: Thromboangiitis obliterans (TAO) poses a higher risk of amputation than atherosclerosis obliterans. It is characterized by onset at a relatively young age. There are currently no clear treatment guidelines for TAO other than smoking cessation. In this study, we aimed to identify factors that could influence a favorable prognosis of TAO. Methods: From January 2009 to December 2019, we retrospectively reviewed the initial symptoms, characteristics, treatments, and disease course of 37 patients (45 limbs) with TAO. Logistic regression analysis was performed to investigate factors affecting the course of symptoms that persisted or worsened despite treatment. Results: Patients' mean age was 37.2±11.4 years, and all patients were men. The mortality rate was 0% during the follow-up period (76.9±51.1 months). All patients were smokers at the time of diagnosis, and 19 patients (51.4%) successfully quit smoking during treatment. When comparing the Rutherford categories before and after treatment, 23 limbs (51.1%) showed improvement, the category was maintained in 11 limbs (24.4%), and 11 limbs (24.4%) worsened. Symptom persistence or exacerbation despite treatment was associated with a higher initial Rutherford category (odds ratio [OR], 1.59; 95% confidence interval [CI], 1.04-2.42; p=0.03) and a higher score of the involved below-knee artery at the time of diagnosis (OR, 2.26; 95% CI, 1.10-4.67; p=0.03). Conclusion: The degree of disease progression at the time of diagnosis significantly affected patients' prognosis. Therefore, early diagnosis and intervention are important to improve the course of TAO.

Searching for Hidden, Painful Osteochondral Lesions of the Ankle in Patients with Chronic Lower Limb Pain - Two Case Reports -

  • Ri, Hyun Su;Lee, Dong Heon;Kim, Kyung Hoon
    • The Korean Journal of Pain
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    • v.26 no.2
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    • pp.164-168
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    • 2013
  • It is easy to overlook osteochondral lesions (OCLs) of the ankle in patients with chronic lower limb pain, such as complex regional pain syndrome (CRPS) or thromboangiitis obliterans (TAO, Buerger's disease). A 57-year-old woman diagnosed with type 1 CRPS, and a 58-year-old man, diagnosed with TAO, complained of tactile and cold allodynia in their lower legs. After neurolytic lumbar sympathethic ganglion block and titration of medications for neuropathic pain, each subject could walk without the aid of crutches. However, they both complained of constant pain on the left ankle during walking. Focal tenderness was noted; subsequent imaging studies revealed OCLs of her talus and his distal tibia, respectively. Immediately after percutaneous osteoplasties, the patients could walk without ankle pain. It is important to consider the presence of a hidden OCL in chronic pain patients that develop weight-bearing pain and complain of localized tenderness on the ankle.

Endovascular Revascularization for the Obstruction after Patch Angioplasty in Buerger's Disease

  • Jun, Hee Jae
    • Journal of Chest Surgery
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    • v.47 no.2
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    • pp.174-177
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    • 2014
  • Surgical revascularization for patients with Buerger's disease is possible only in a few cases, due to the diffuse segmental involvement and the lack of distal runoff vessels available for bypass surgery. We encountered a case of resting pain in the right foot, coldness with dysesthesia, and cyanosis on the right 1st toe. The patient was treated with an endovascular intervention after vein patch angioplasty failed due to an inflammatory reaction of Buerger's disease. We suggest that an endovascular procedure can be an effective treatment, even in addition to more conservative and surgical management, in patients with Buerger's disease and critical limb ischemia.

The Clinical Evaluation of the Epidurally Administered Clonidine for the Pain Control of the Patients with Buerger's Disease (Buerger병 환자의 통증 치료에서 경막외 Clonidine 투여의 임상적 고찰)

  • Ryu, Keon-Hee;Kil, Hyeon-Ja;Suh, Jae-Hyun;Kim, Sung-Nyeun
    • The Korean Journal of Pain
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    • v.8 no.2
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    • pp.286-292
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    • 1995
  • Buerger's disease(Thromboangiitis Obliterans) is characterized by peripheral arterial occlusion of the extremities in young smokers, and leading to ischemia of the tissue and gangrene. Most of these patients suffered from severe pain. therapy for Buerger's disease not enable to undergo reconstructive arterial surgery has been discouraging while multiple modes of analgesics have advanced. Eight subjects who had been operated due to Buerger's disease or diagnosed with this disease were evaluated retrospectively. Continuous epidural block was done at L 2~3 or L3~4 intervertebral space and multiday continuous infusor was connected to epidural catheter. The content of the infusor was clonidine-bupivacaine or clonidine-morphine-bupivacaine mixture. The minimum dose of clonidine was 75 ${\mu}g/day$ and the maximum 450 ${\mu}g/day$. The results were as follows: The analgesia produced by clonidine was superior to any other analgesics. 2) The incidence of the side effects produced by clonidine-bupivacaine mixture were less than that of clonidine-morphine-bupivacaine mixture. 3) Minimum dose of clonidine for the pain relief was required more than 225 ${\mu}g$ per day. From the above results, we recommend that clonidine is an effective agent to provide pain relief for the patients with Buerger's disease.

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