• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.1
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• pp.193-195
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• 2006

The effects of ethanol extract from Lepidolaena clavigera (L. clavigera) on antifungal activity were investigated. The crude ethanol extract of L. clavigera inhibited the growth of the Gram positive bacterium Bacillus subtilis ATCC 19659, (1 mm inhibition zone at 150 ${\mu}g/disc$) and the dermatophytic fungus Trichophyon mentagrophyes ATCC 28185, (2 mm inhibition zone at 150 ${\mu}g/disc$), and cytotoxic to P388 murine leukaemia cells ATCC CCL 46 P388D1, (IC50 >12,500 ${\mu}g/mL\;at\;150\;{\mu}g/disc$) and cytotoxic to BSC monkey kidney cells (@ 5 mg/mL, 150 ${\mu}g/disc$; ++: 50% activity). We suppose that this crude ethanol extract of L. clavigera is the antifungal activity.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.4
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• pp.1068-1072
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• 2005

The chlororinated bibenzyl compound (1) inhibited the growth of the Gram positive bacterium Bacillus subtilis ATCC 19659, (2mm inhibition zone at $30{\mu}g/disc$), Candida albicans ATCC 14053, (2mm inhibition zone at $30{\mu}g/disc$), and the dermatophytic fungus Trichophyon mentagrophtes ATCC 28185, (3mm inhibition zone at $30{\mu}g/disc$).

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.6
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• pp.1656-1658
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• 2005

The effects of chloroform extract from Lepidolaena tayiorii (L. tayiorii) on antifungal activity were investigated. The crude chloroform extract of L. tayiorii inhibited the growth of the Gram positive bacteria Bacillus subtilis ATCC 19659, (5 mm inhibition zone at $150{\mu}g/disc$) and the dermatophytic fungus Trichophyton mentagrophytes ATCC 28185, (6 mm inhibition zone at $150{\mu}g/disc$), and cytotoxic to P388 murine leukaemia cells ATCC CCL 46 P388D1, ($IC_{50}\;405.0{\mu}g/mL\;at\;150{\mu}g$/disc) and cytotoxic to BSC monkey kidney cells (@ 5 mg/mL, $150{\mu}g/disc;$ +++: 100% activity). We suppose that this crude chloroform extract of L. tayiorii is the strong antimicrobial and cytotoxic activities.