• 제목/요약/키워드: UD

검색결과 290건 처리시간 0.026초

Flexural behavior of sandwich beams with novel triaxially woven fabric composite skins

  • Al-Fasih, M.Y.;Kueh, A.B.H.;Ibrahim, M.H.W.
    • Steel and Composite Structures
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    • 제34권2호
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    • pp.299-308
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    • 2020
  • This study aims to carry out the experimental and numerical investigation on the flexural behavior of sandwich honeycomb composite (SHC) beams reinforced with novel triaxially woven fabric composite skins. Different stacking sequences of the carbon fiber reinforcement polymer (CFRP) laminate; i.e., 0°-direction of TW (TW0), 0°-direction of UD (UD0), and 90°-direction of UD (UD90) were studied, from which the flexural behavior of SHC beam behaviors reinforced with TW0/UD0 or TW0/UD90 novel laminated skins were compared with those reinforced with UD0/90 conventional laminated skins under four-point loading. Generally, TW0/UD0 SHC beams displayed the same flexural stiffness as UD0/90 SHC beams in terms of load-deflection relationships. In contrast, TW0/UD90 SHC beams showed a 70% lower efficiency than those of UD0/90 SHC. Hence, the TW0/UD0 laminate arrangement is more effective with a mass reduction of 39% compared with UD0/90 for SHC beams, although their stiffness and shear strength are practically identical.

AOM/DSS 유발 대장암에 대한 유근피(楡根皮)와 백화사설초(白花蛇舌草) 단일 및 배합 추출물의 항암 및 항염 효과 (Anti-neoplastic and Anti-inflammatory Effects of Single and Mixed Extracts of Ulmus Davidiana and Oldenlandia Diffusa on Azoxymethane/dextran Sodium Sulfate-induced Colonic Neoplasms)

  • 이선아;백동기;문구
    • 대한한방내과학회지
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    • 제38권6호
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    • pp.863-876
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    • 2017
  • Objectives: The aim of this experimental study was to evaluate the anti-neoplastic and anti-inflammatory effects of single and mixed extracts of Ulmus davidiana (UD) and Oldenlandia diffusa (OD) on azoxymethane/dextran sodium sulfate (AOM/DSS)-induced colonic neoplasms in mice. Methods: AOM/DSS induces colitis-associated colonic neoplasms in mice. Mice were divided into seven groups: normal-no inducement and no treatment; control-colonic neoplasms with no treatment; UD-colonic neoplasms and treatment with UD; OD-colonic neoplasms and treatment with OD; UD1+OD1-colonic neoplasms and treatment with UD1 and OD1. UD1+OD2-colonic neoplasms and treatment with UD1 and OD2; UD2+OD1-colonic neoplasms and treatment with UD2 and OD1. Single and mixed preparations of UD and OD were applied to mice for six weeks. The colon length and weight and histopathologic changes of colon tissue were observed. Serum pro-inflammatory cytokines, including tumor necrosis factor-alpha ($TNF-{\alpha}$) and interleukin-6 (IL-6), were determined by enzyme-linked immunosorbent assay. The mRNA expression levels of Bax, Bcl-2, and interferon-gamma ($INF-{\gamma}$) were measured by RT-PCR. Results: The colon length was significantly increased in OD, UD1+OD2, and UD2+OD1 mice, and the colon weight was significantly decreased in OD and UD1+OD2 mice. The morphological change of colon epithelial cells was more suppressed in complex-treatment groups than in single-treatment groups. The inhibitory effect on inflammatory cell invasion was especially shown in UD1+OD2 mice. The serum level of the pro-inflammatory $TNF-{\alpha}$ was decreased in all complex-treatment groups, and the IL-6 level was decreased in UD1+OD1 mice. Single-treatment groups had an increase in the mRNA expression of the pro-apoptosis regulator Bax, and UD2+OD1 decreased the mRNA expression of the anti-apoptosis regulator Bcl-2. The mRNA expression of $INF-{\gamma}$ associated with inflammation was decreased in OD and UD1+OD2 mice. Conclusions: This study suggests that single and mixed extracts of Ulmus davidiana and Oldenlandia diffusa have anti-neoplastic and anti-inflammatory effects on AOM/DSS-induced colonic neoplasms in mice. Therefore, we conclude that UD, OD, and a mixture of UD and OD are potential therapeutic agents for colitis-associated colonic neoplasms.

전주시 건지산 숲길 Universal Design 사업 이용후 평가 (The Post Occupancy Evaluation of the Universal Design Project on Geonjisan Forest Trail Jeonju City, South Korea)

  • 박선아;이명우
    • 한국조경학회지
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    • 제40권6호
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    • pp.60-69
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    • 2012
  • 전주시 건지산 UD 숲길은 2008년 한국토지공사 초록사회 만들기 공모사업의 일환으로 전북생명의 숲이 주관하여 설계 및 시공이 추진되었다. 이 연구는 이용자 만족도, 이용자 수 조사의 이용후 평가를 통해 UD 숲길 설계의 적정성을 평가하는데 목적이 있다. 연구결과, 건지산 UD 숲길의 주이용자는 60대 이상의 지역주민이 전체이용자의 37%를 차지하며, 이용목적은 산책과 휴식 51.5%, 운동 및 재활치료 40.6%로 나타났다. UD 숲길 만족도는 5점 리커트 척도에서 3.91로 나타났고, 전체 만족도에 영향을 미치는 주요 요소는 관리, 이용충돌, 폭과 경사에 대한 만족도 순서로 나타났다. 이용자수 조사에서 교통약자는 UD 숲길 45명, 기존 숲길 6명으로 나타났다. 연구결과를 통해 건지산 UD 숲길은 교통약자의 이용을 유도하고, 일반인과 교류할 수 있는 기회를 제공하는 것으로 나타났다. 또한 UD 숲길 주변의 높은 경관만족도는 기존지형과 수목을 가능한 보존하고, 목재 데크를 설치함으로써 기존 자연경관이 잘 유지된 점을 나타냈다. 건지산 UD 숲길의 이용후 평가는 도시숲길 조성시 장애인, 노인, 약자, 임산부, 어린이 등 다양한 신체조건의 이용자들이 안전하고 편리하게 이용할 수 있도록 유니버설 디자인 개념의 도입 필요성을 나타내주고 있다.

MPEG-UD 표준을 준수하는 비쥬얼 커뮤니케이션 데모 프로그램 개발 (Implementation of Demo Program for Visual Communication in Compliance with MPEG-21 Part 22: User Description)

  • 임해진;최장식;전진영;변형기
    • 센서학회지
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    • 제25권4호
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    • pp.297-301
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    • 2016
  • ISO/IEC JTC1/SC29WG11 MPEG has been standardizing UD(user description) to give a user personalized recommendation services. Besides, CD(context description), service description(SD), and recommendation description(RD) are recently being standardized by UD Adhoc Group in MPEG with an advanced UD to cope with needs of current and upcoming services such as augmented reality and social network. The descriptions was reflected to MPEG-UD WD(Working Draft) at MPEG $107^{th}$ meeting and the document was finally approved as international standard by national bodies with standard number(ISO/IEC IS 21000-22 UD) at $114^{th}$ MPEG meeting. In addition, reference software WD to validate conformance of UD standard was approved at $113^{th}$ MPEG meeting. In this paper, we developed a demo program for visual communication according to guideline defined in reference software WD to validate the reference software as well as UD standard.

Inhibitory effect of Ulmus davidiana Planch extracts on bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts

  • Park, Jun-Sung;Kim, Kyung-Ho;Jo, Hyun-Seog;Kim, Kap-Sung;Hwang, Min-Seob
    • Journal of Acupuncture Research
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    • 제22권2호
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    • pp.55-70
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    • 2005
  • Objective: Ulmus davidiana Planch (Ulmaceae) has long been known to have anti-inflammnatory in the traditional Korean medicine. UD has been reported as a good enhancer for bone healing. Methods : In this experiment, we investigate the Inhibitory effects of UD on bone resorption using the bone cells culture. Different concentrations of crude extract of UD were added to mouse bone cells culture. The mitochondria activity of the bone cells after exposure was determined by colorimetric MIT assay. It was demonstrated that UD has potential effects on bone cells culture without any cytotoxicity. The most effective concentration of UD on bone cells were $100\;{\mu}g/ml$. Cathepsin K (Cat K) is the major cysteine protease expressed in osteoclasts and is thought to play a key role in matrix degradation during bone resorption. Results : When mouse long bone cells including osteoclasts and osteoblast were treated with the PI3-Kinase inhibitor, wortmannin (WT), WT prevented the osteoclast-mediated intracellular processing of Cat K. Similarly, treatment of osteoclasts-containing long bone cells with UD extracts prevented the intracellular maturation of Cat K, suggesting that UD may disrupt the intracellular trafficking of pro Cat K. This is similar to that of WT. Since secreted proenzymes have the potential to reenter the cell via mannose-6-phosphate (M6P) receptor, to prevent this possibility, we tested WT and UD in the absence or presence of M6P. Inhibition of Cat K processing by WT or UD was observed in a dose-dependent manner. Furthermore, the addition of M6P resulted in enhanced potency of WT and UD. Conclusion : UD dose-dependently inhibited in vitro bone resorption with a potency similar to that observed for inhibition of Cat K processing.

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일본어의 Universal Dependency 태그셋 적용 사례 연구 - 한국어와의 비교를 중심으로 (A Case Study on Universal Dependency Tagsets of Japanes)

  • 이진;한지윤;김한샘
    • 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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    • 한국정보과학회언어공학연구회 2018년도 제30회 한글 및 한국어 정보처리 학술대회
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    • pp.323-328
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    • 2018
  • 한국어는 교착어적 특성으로 인하여 어미와 조사가 매우 발달되어 있다. 그러므로 영어와 같은 굴절어를 중심으로 설계된 UD를 한국어에 적용하는 것에는 많은 어려움이 있다. 이를 해결하기 위해서 형태통사적 특성이 유사한 일본의 UD 적용 사례를 살펴보고 한국어의 UD 적용 양상과의 비교 분석을 통해서 한국어의 UD 적용 및 개선 방안을 고찰해 보고자 한다. 한국어와 일본어는 동일한 교착어로서 비슷한 특성을 지니고 있으나, 주석의 기본 단위 설정에서 차이를 보이면서 UD를 적용하는 양상이 달라졌음을 확인하였다. 일본어의 UD 주석에서 형태 분석 기본 단위인 단단위(Short unit word, 長單位)를 기본 구문 주석 단위로 하되 장단위(Long unit word, 短單位)와 문절 정보를 이용하는 것처럼, 한국어에서도 형태 분석 단위를 기준으로 의존 관계를 주석하는 방안에 대해서도 고려할 필요가 있다.

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Vasorelaxing Activity of Ulmus davidiana Ethanol Extracts in Rats: Activation of Endothelial Nitric Oxide Synthase

  • Cho, Eun-Jung;Park, Myoung-Soo;Kim, Sahng-Seop;Kang, Gun;Choi, Sung-A;Lee, Yoo-Rhan;Chang, Seok-Jong;Lee, Kwon-Ho;Lee, Sang-Do;Park, Jin-Bong;Jeon, Byeong-Hwa
    • The Korean Journal of Physiology and Pharmacology
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    • 제15권6호
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    • pp.339-344
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    • 2011
  • Ulmus davidiana var. japonica Rehder (Urticales: Ulmaceae) (UD) is a tree widespread in northeast Asia. It is traditionally used for anticancer and anti-inflammatory therapy. The present study investigated the effect of an ethanol extract of UD on vascular tension and its underlying mechanism in rats. The dried root bark of UD was ground and extracted with 80% ethanol. The prepared UD extract was used in further analysis. The effect of UD on the cell viability, vasoreactivity and hemodynamics were investigated using propidium iodide staining in cultured cells, isometric tension recording and blood pressure analysis, respectively. Low dose of UD ($10{\sim}100{\mu}g/ml)$ did not affect endothelial cell viability, but high dose of UD reduced cell viability. UD induced vasorelaxation in the range of $0.1{\sim}10{\mu}g/ml$ with an $ED_{50}$ value of $2{\mu}g/ml$. UD-induced vasorelaxation was completely abolished by removal of the endothelium or by pre-treatment with L-NAME, an inhibitor of nitric oxide synthase. UD inhibited calcium influx induced by phenylephrine and high $K^+$ and also completely abolished the effect of L-NAME. Intravenous injection of UD extracts (10~100 mg/kg) decreased arterial and ventricular pressure in a dose-dependent manner. Moreover, UD extracts reduced the ventricular contractility (+dP/dt) in anesthetized rats. However, UD-induced hypotensive actions were minimized in L-NAME-treated rats. Taken together, out results showed that UD induced vasorelaxation and has antihypertensive properties, which may be due the activation of nitric oxide synthase in endothelium.

3GPP UDC 성능 향상에 관한 연구 (A Study on the performance improvement of 3GPP User Data Convergence)

  • 전승훈;박철수;김진태;이성화
    • 한국인터넷방송통신학회논문지
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    • 제19권2호
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    • pp.53-58
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    • 2019
  • 가입자 및 디바이스의 폭발적인 증가와 복잡한 서비스에 대한 수요와 다양한 요구가 늘어나면서 이를 충족하기 위한 네트워크의 진화는 계속되고 있다. 특히, LTE를 기점으로 하여 LTE 네트워크에서 늘어나는 트래픽과 시그널링 폭증 및 5G로 발전을 위하여 다양한 기술적인 대안들이 나오고 있다. 본 연구는 늘어난 부하와 정보 관리의 복잡도로 인해 야기되는 UDC 성능 문제의 개선에 관한 것으로, 특히, 3GPP 표준 LDAP기반의 Ud 인터페이스 통신 프로토콜과 Private기반의 Ud 인터페이스 통신 프로토콜의 수신 메시지 수 및 응답 메시지수의 처리에 대한 비교 실험을 수행하였다. 결과적으로 새로 정의된 Ud 인터페이스 통신 프로토콜이 Ud 인터페이스방식에 기반한 LDAP보다 평균 1.7배 성능 개선이 이루어진 것을 확인하였다.

Assessment of Universal Design for Seoullo 7017 in Seoul, Korea - Using a New Seven Universal Design Principles -

  • Yoo, Jieun;Kim, Jin-Oh
    • 휴양 및 경관연구
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    • 제12권4호
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    • pp.35-44
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    • 2018
  • The purpose of this research is to evaluate Seoullo 7017 based on Universal Design (UD) principles and guidelines. To derive UD principles applicable to the site context, we used the 2017 Seoul Universal Design Guideline and assessment index provided by the Universal Design Research Center and established 11 evaluation criteria. With respect to research methods, a literature review and on-site field survey were applied, through which we derived UD principles and evaluation criteria to identify UD problems. The 11 evaluation criteria consist of pedestrian space, facilities, access, main entrance, parking lots, trails, restrooms, convenience facilities, information facilities, rest areas, and playgrounds, and these were associated with UD principles for evaluation. As a result, the main entrance had the highest UD score, while parking lots had the lowest in terms of equity, safety, simplicity, and accessibility. Restrooms received a lower UD score because of poor conditions of security and alert systems. Rest areas were found to be uncomfortable for disabled people. With respect to the internal trails, we found the lack of braille block and irregular placement of planting pots made blind people uncomfortable when walking. In terms of UD principles, flexibility received the highest score, followed by amenity, equity, simplicity, tolerance, accessibility, and safety. Flexibility received the highest score, owing to the provision of proper information about convenience facilities and trails, while safety received the lowest, based on poor access to parking lots, inadequate paving materials and colors, and a lack of 24-hour security systems. We hope this research contributes to improving the universal design, so that people are not discriminated against in the use of the park in terms of age, sex, or physical disability. We expect the study to help facilitate empirical studies to verify UD principles and provide improved quality of UD for Seoullo 7017.

MPEG-UD 표준 요소 검증을 위한 콘텍스트 기반 추천 시스템 구현 (Implementation of Context-Based Recommendation System to Verify Schema of MPEG-UD Standard)

  • 백종현;최장식;변형기
    • 센서학회지
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    • 제24권1호
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    • pp.62-68
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    • 2015
  • The MPEG user description (MPEG-UD) which is a standard under exploration to ensure interoperability among customized recommendation services has been contributed since MPEG $104^{th}$ meeting at 2013. Twenty-two use cases that were divided into different applications have been proposed in the MEPG meetings. Most of use cases were referred to specific and restricted regarding to applications, it appears to miss an overall and explicit infra-structure. In this paper we describe a reference model, namely methodology to overcome aforementioned problems. Thereafter, we have applied reference model to context-based recommendation system to demonstrate the methodology and MPEG-UD schemas. In addition, we propose a development process of recommendation system in compliance with MPEG-UD.