• Asian-Australasian Journal of Animal Sciences
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• v.2 no.3
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• pp.145-146
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• 1989

• Asian-Australasian Journal of Animal Sciences
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• v.2 no.3
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• pp.177-178
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• 1989

• Journal of Biomedical Engineering Research
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• v.12 no.3
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• pp.177-184
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• 1991

Characteristics of the lung inflation and deflation reflexes were measured at various temperatrues on the cervical vagi in five anesthetized mongrel dogs. Nerve temperature was maintained at the body temperature, and $2-14^{\circ}C$ with $2^{\circ}C$ apart using a specially designed automated vagal cooling apparatus with an accuracy to within ${\pm}0.1^{\circ}C$ at each temperature. The inflation reflex was blocked abruptly at $8-10^{\circ}C$. The deflation reflex started weakened at $14^{\circ}C$, thereafter showed a gradual blockade with the temperature decreased with a substantial variance among the animals. It was approximately 75% blocked at $2-6^{\circ}C$. These differences in temperature characteristics made it hard to differentiate the deflation reflex from the inflation reflex. In one animal, however, the inflation reflex was completely blocked with the deflation reflex almost alive at $6-8^{\circ}C$. This suegests that differential cold blockade of the vagal reflexes can be done only in selected subjects. Fur- thermore, the fact that these two reflexes were blocked at different temperatures may be due to the differences in the nerve fiber size and the changes in the conduction velocity with temperature.

• Journal of Biomedical Engineering Research
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• v.4 no.1
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• pp.3-8
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• 1983

Characteristics of the lung inflation and deflation reflexes were measured at various temperatures on the cervical vagi in five anesthetized mongrel dogs. Nerve temperature was maintained at the body temperature, and 2-14˚C with 2˚C apart using a specially designed automated vagal cooling apparatus with an accuracy to within $\pm$ 0.1˚c at each temperature. The inflation reflex was blocked abruptly at 8-10˚C. The deflation reflex started weakened at 14˚C, thereafter showed a gradual blockade with the temperature decreased with a substantial variance among the animals.It was approximately 75% blocked at 2-5˚C. These differences in temperature characteristics made it hard to differentiate the deflation reflex from the inflation reflex. In one animal, however, the inflation reflex was completely blocked with the deflation reflex almost alive at 6-8˚C. This suggests that differential cold blockade of the vagal reflexes can be done only in selected subjects. Furthermore, the fact that these two reflexes were blocked at different temperatures may be due to the differences in the nerve fiber size and the changes in the conduction velocity with temperature.

• Journal of Chest Surgery
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• v.51 no.5
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• pp.344-349
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• 2018

Background: We report our surgical technique for nonintubated uniportal video-assisted thoracoscopic surgery (VATS) pulmonary resection and early postoperative outcomes at a single center. Methods: Between January and July 2017, 40 consecutive patients underwent nonintubated uniportal VATS pulmonary resection. Multilevel intercostal nerve block was performed using local anesthesia in all patients, and an intrathoracic vagal blockade was performed in 35 patients (87.5%). Results: Twenty-nine procedures (72.5%) were performed in patients with lung cancer (21 lobectomies, 6 segmentectomies, and 2 wedge resections), and 11 (27.5%) in patients with pulmonary metastases, benign lung disease, or pleural disease. The mean anesthesia time was 166.8 minutes, and the mean operative duration was 125.9 minutes. The mean postoperative chest tube duration was 3.2 days, and the mean hospital stay was 5.8 days. There were 3 conversions (7.5%) to intubation due to intraoperative hypoxemia and 1 conversion (2.5%) to multiportal VATS due to injury of the segmental artery. There were 7 complications (17.5%), including 3 cases of prolonged air leak, 2 cases of chylothorax, 1 case of pleural effusion, and 1 case of pneumonia. There was no in-hospital mortality. Conclusion: Nonintubated uniportal VATS appears to be a feasible and valid surgical option, depending on the surgeon's experience, for appropriately selected patients.