• Title/Summary/Keyword: case-controlled study

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Acupuncture for the Treatment of Burns: A Systematic Review of Randomized Controlled Trials and Case Controlled Trials (화상의 침 치료에 대한 체계적 문헌고찰)

  • Lee, Jieun;Jeong, Seoyoon;Choi, Yoomin;Jeong, Minjeong
    • The Journal of Pediatrics of Korean Medicine
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    • v.31 no.4
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    • pp.19-30
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    • 2017
  • Objectives The study was conducted to evaluate the acupuncture treatment for burns by reviewing international randomized controlled studies and case controlled studies. Methods In the review, ten academic literature archives; NDSL, OASIS, PubMed, Cochrane library, CNKI, WANFANG, CINAHL, J-STAGE, CiNii, and EMBASE were used as the main databases to search for the randomized controlled trials or the case controlled trials about acupuncture treatment of burns using the keywords "burns AND acupuncture", "burn AND acupuncture", and "scald AND acupuncture". Results Initially, a total of 852 studies were founded except duplicate studies. 801 studies were excluded after screening of title and abstract. After reviewing 51 papers, a total of four randomized controlled trials and two case controlled trials were selected. These studies were analyzed by year, subjects, treatment intervention, evaluation criteria, treatment effect, adverse events, and 'Risk of Bias' assessment for randomized studies and non-randomized studies. From the six papers out of 51 papers those were reviewed, patients with burns were divided into two groups. The experimental group received acupuncture treatment, while the control group did not. The results of the completed studies have shown that the experimental group receiving acupuncture treatment demonstrated significant improvement compared to the control group, and there was no serious adverse events. Conclusions According to some of the studies, acupuncture in burn treatment is worth to try. However, additional well-designed randomized controlled studies will be required to justify the effectiveness of acupuncture treatment of burns.

A Review of Clinical Study on Jungsongouhyul Pharmacopuncture Treatment Published in Korea (중성어혈약침 치료에 대한 임상논문 고찰 - 국내학술지를 중심으로)

  • Yoon, Jeong-Won;Kim, Soon-Joong
    • Journal of Korean Medicine Rehabilitation
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    • v.27 no.4
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    • pp.75-84
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    • 2017
  • Objectives To review the case studies and controlled studies about Jungsongouhyul pharmacopuncture treatment. Methods We searched 92 studies about Jungsongouhyul pharmacopuncture from 6 Korean web databases, using words 'Jungsongouhyul', 'Jungsongouhyul and pharmacopuncture', 'ouhyulpharmacopuncture' and 'ouhyul and pharmacopuncture' in Korean alphabet. We removed 63 duplicated studies. And we excluded 12 studies by reviewing abstract and the contents of a study. Results We selected 5 case studies and 12 controlled studies, excluding experimental research and study not on humans, not using the Jungsongouhyul pharmacopuncture for major treatment. Jungsongouhyul pharmacopuncture was used mostly in whiplash injury and all studies showed that Jungsongouhyul pharmacopuncture is effective treatment. But we found some lacking parts with study design in most studies. Conclusions We found out that Jungsongouhyul pharmacopuncture is effective in various diseases. But we need to do more well-designed study to increasing reliability of Jungsongouhyul pharmacopuncture treatment.

An Intensive Review On Clinical Thesis about Hwangryunhaedok-tang Pharmacopuncture Treatment: Focused on Case Reports and Controlled Studies in Korean Academic Journals (황련해독탕약침 치료에 대한 임상 논문 고찰: 국내 학술지의 증례보고와 대조군 연구 중심으로)

  • Lee, Soo-Hwan;Kim, Soon-Joong
    • Journal of Korean Medicine Rehabilitation
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    • v.29 no.2
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    • pp.171-188
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    • 2019
  • Objectives The purpose of this thesis is to compare and analyze outcomes of case studies and controlled studies about Hwangryunhaedok-tang (HHT) pharmacopuncture in clinical studies. Based on these studies reporting clinical effects by using HHT pharmacopuncture, we object to deduct the comparative review in applying clinical disorders limitedly. And conclusionally, by using this comparative review, we aim to make the fine evidence in treating clinical specific diseases. Methods We searched 106 studies about HHT pharmacopuncture from 6 Korean web databases by using in Korean word 'Hwangryunhaedok-tang pharmacopuncture'. This search had been progressed throughout 1 month (January, 2019). There was 106 thesis and we excluded studies that are not related to HHT pharmacopuncture, experimental research, not the case report or randomized controlled trials, non-randomized controlled trials, not using HHT pharmacopuncture, not using only one pharmacopuncture, and not using HHT pharmacopuncture for major treating method. As a result, 39 thesis are selected as a population. Results We analyzed 34 case reports and 5 controlled studies. As the final outcome, HHT pharmacopuncture was used in musculoskeletal diseases, dermatopathy, and 32 specific diseases. Conclusions After analyzing 39 studies, effective symptom changes clinically and statistically by using HHT pharmacopuncture herbal acupuncture were identified. However, these thesis designs were reported deficiently in many parts such as not excluding other confounding variables. After modifying defects of thesis design and conduct study, it can play a role as the evidence using HHT pharmacopuncture more precisely.

Impact of Aerobic Exercise and Acupuncture Treatment on Obese Patients; A Retrospective Case-Controlled Study

  • Sezgin, Yilmaz;Kaplan, Askin Keskin
    • Journal of Pharmacopuncture
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    • v.24 no.2
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    • pp.54-58
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    • 2021
  • Objectives: The purpose of this study is to investigate the effects of aerobic exercise and acupuncture treatment in obese patients. Methods: The effects of exercise in obese patients receiving acupuncture therapy were investigated in this retrospective, case-controlled study in which subjects complying with exercise were enrolled in the case and non-compliers were enrolled in the control group. Results: There was a statically significant weight loss in both the study case group (94.39 ± 20.36; 88.91 ± 19.00; n = 22; p = 0.001) and the control group (103.18 ± 21.92; 99.56 ± 21.92; n = 34; p = 0.001) after 3 months. Weight loss occurred in all 22 patients in the case group. In the control group, while weight loss occurred in 27 of the 34 patients, weight gain occurred in three patients. Conclusion: In conclusion, the addition of modalities such as acupuncture, exercise and diet may provide effective improvement in weight control.

The Assessment of Risk of Bias on Clinical Trials of Korean Medicine for Alopecia (탈모증의 한약제제 임상연구에 대한 비뚤림 위험 평가)

  • Ryu, Deok-hyun;Roh, Seok-sun
    • Journal of Haehwa Medicine
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    • v.24 no.1
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    • pp.25-36
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    • 2015
  • Objective : This study aims to evaluate a risk of bias by Risk of Bias tool and RoBANS(Risk of Bias Assessment tool for Non-randomized Study) tool for clinical trial papers proving treatment effect of herbs to alopecia and provides the newest reason of effectiveness of herbs to alopecia. Methos : Data were collected through electronic database including NDSL, KISS, KMBASE, Koreantk, OASIS, KoreaMed, KISTI, Pubmd, Cochrane CENTRAL and CINAHL. Two experts in Oriental Medince assessed risk of bias of randomized controlled trials by Cochrane group's Risk of Bias tool and non-randomized controlled trials by RoBANS tool after searching, reviewing and selecting papers. Results : Total number of selected trials is 20 including 4 randomized controlled trials, 13 non-randomized controlled trials and 3 case reports. This study evaluates the risk of bias of 17 papers including 4 randomized controlled trials and 13 non-randomized controlled trials except 3 case reports by risk of bias tool and RoBANS tool. All papers of randomized controlled trials are evaluated unclear for random sequence generation and allocation concealment as there are no word on them. And all papers of non-randomized controlled trials are evaluated unclear for blinding of outcome assessments and relatively low for others. Conclusion : We must try to specify concretely methods of allocation concealment after planning and practicing it for reducing a selection bias in randomized controlled trials. Also report a reason of missing value and blinding outcome assessments. And we have to agonize and mention methods of blinding of researchers for reducing a detection bias in non-randomized controlled trials.

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A Comparative Review on Carthmi-Flos Pharmacopuncture Treatment - Focused on Clinical Study (홍화약침 시술에 관한 임상논문 비교연구)

  • Lee, Soo-Hwan;Yoon, Jeong-Won;Kim, Soon-Joong
    • Journal of Korean Medicine Rehabilitation
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    • v.27 no.4
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    • pp.55-65
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    • 2017
  • Objectives The purpose of this review is to analyze results of case studies and controlled studies about Carthmi-Flos pharmacopuncture. Based on the review, authors desire to suggest the study model including precise information and evident the effect of Carthmi-Flos pharmacopuncture objectively in treating clinical disorders. Methods We search 44 studies about Carthmi-Flos pharmacopuncture from 6 Korean web databases, using words 'Carthmi-Flos pharmacopuncture' in Korean alphabet. This study had been conducted throughout 1 month (July, 2017). We selected case studies and controlled trials in investigated 44 thesis, excluding experimental research and thesis not using the Carthmi-Flos pharmacopuncture for major treatment. Results We analyze 13 case reports and 7 controlled trials. As a result, Carthmi-Flos Pharmacopuncture was used mostly in musculoskeletal, neurological diseases. But this can be applied to internal diseases. Disorders reported effectively were carpal tunnel syndrome, degenerative knee joint arthritis, posterior neck pain, low back pain, radial nerve palsy, shoulder pain, lumbar compression fracture, alopecia areata, chronic daily headache, duverney fracture, oligomenorrhea, cervical disc herniation, rheumatoid arthritis and cervical headache. Conclusions As we analyzed, Carthmi-Flos pharmacopuncture is specifically effective in musculoskeletal and neurologic diseases. But there are various problems in study design. To design accurately, the study design should include much more specific information. And the result can be more precise by excluding other methods.

A Study of Supersonic Flow Around Lateral Jet Controlled Missile (측 추력 제어 미사일 주위의 초음속 유동현상 연구)

  • Min Byung-Young;Lee Jae-Woo;Byun Yung-Hwan;Hyun Jae-Soo
    • 한국전산유체공학회:학술대회논문집
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    • 2002.10a
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    • pp.28-34
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    • 2002
  • A computational study of supersonic flow around lateral jet controlled missile has been performed. For this study, three dimensional Navier-Stokes code(AADL3D) has been developed. Spalart-Allmaras one equation turbulence model has been implemented on the AADL3D code for relatively rapid computational time. For the validation of developed code, AADL3D, pressure distributions on an ogive-cylinder body has been compared with experimental data. Also, the shock structure of sonic jet on the flat plate in the supersonic flow field has been compared with experimental flow visualization result to see the analysis capability of freestream-jet interaction case. A case study has been performed through comparing the normal force coefficient and the moment coefficient of missile body for several jet flow conditions. Current results will be used to the optimum design of a lateral jet controlled missile.

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A Case Study on the Analysis of Man/Multi-Machine System Using Simulation (시뮬레이션을 이용한 작업자/복수기계 가동분석에 대한 사례연구)

  • Moon, Dug-Hee;Song, Cheng;Choi Mi-Jin;Jung, Jong-Yun
    • Journal of the Korea Society for Simulation
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    • v.12 no.1
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    • pp.21-34
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    • 2003
  • This paper deals with a case study of workload analysis of an operator in an automatic line for machining the race of ball bearing. Eleven machines and three hoppers are installed in the line which is operated by an operator. The elements of operation are separated into machine controlled elements, operator controlled elements and machine/operator controlled elements. In order to analyze the system, time and motion studies are used for gathering input data for the simulation model. The first objective of this study is to evaluate whether the workload of operator is reasonable or not. The second objective is to increase throughput by reducing tact time and the last one is to increase frequencies of inspection by reducing interval. Thus we suggest some ideas for improvement, and as a result, the throughput is improved about 9%. In spite of the increasing of throughput, the allowance of operator is also increased about 4%.

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The effects of Very Low Calorie Diet using meal replacements that contain Herbal extracts on weight reduction and health promotion (한약추출물을 함유한 식사대용식이가 체중감량과 초저열량식이의 부작용에 미치는 영향)

  • Choi, Seung;Kim, Ji-Young;Jang, Yu-Gyung;Kim, Sang-Yeon;Park, Mi-Hyun;Hong, Seong-Gil;Hwang, Seong-Ju;Choi, Hyung-Suk
    • Journal of Korean Medicine for Obesity Research
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    • v.4 no.1
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    • pp.81-94
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    • 2004
  • Background: The VLCD that supplies only 400-800kcal meal per day has a lot of problems and can severely harm the health. Certain herbs are known to the side-effects such as weakness, skin dehydration, and dizziness. If VLCD with meal-replacement containing these hearbs can effectively minimize the side-effects, it make weight management easier and reduce any possible danger the health. Objectives: This prospective, double-blinded study is intended to compare the severity of symptoms induced by VLCD and weight loss between the case group supplied with meal-replacement herbal extracts(n=29) and controlled group supplied with meal-replacement not containing herbal extracts(n=29). This was with 52 volunteers for 4 weeks. The measurements of this experiment were as follows: symptoms caused by patients' subjective judgments, the result of blood test illustratingerol level, total protein etc., and changes in overall weight, fat mass and lean body mass. Result: we concluded that there are no significant differences in weight change between case group and controlled group, and that the total protein at the end of trial was significantly higher in case group than in controlled group, and triglyceride level at the end of trial was lower in case group than in controlled group. As expected, the side-effects such as hair loss and dehydration in skin are also lessin case group than in controlled group.

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Efficacy and Safety of Gabapentin in the Treatment of Chronic Cough: A Systematic Review

  • Shi, Guanglin;Shen, Qin;Zhang, Caixin;Ma, Jun;Mohammed, Anaz;Zhao, Huan
    • Tuberculosis and Respiratory Diseases
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    • v.81 no.3
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    • pp.167-174
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    • 2018
  • Despite recent clinical guidelines, the optimal therapeutic strategy for the management of refractory chronic cough is still a challenge. The present systematic review was designed to assess the evidence for efficacy and safety of gabapentin in the treatment of chronic cough. A systematic search of PubMed, Embase, Cochrane Library databases, and publications cited in bibliographies was performed. Articles were searched by two reviewers with a priori criteria for study selection. Seven relevant articles were identified, including two randomized controlled trials, one prospective case-series designed with consecutive patients, one retrospective case series of consecutive patients, one retrospective case series with unknown consecutive status, and two case reports comprising six and two patients, respectively. Improvements were detected in cough-specific quality of life (Leicester Cough Questionnaire score) and cough severity (visual analogue scale score) following gabapentin treatment in randomized controlled trials. The results of prospective case-series showed that the rate of overall improvement of cough and sensory neuropathy with gabapentin was 68%. Gabapentin treatment of patients with chronic cough showed superior efficacy and a good safety record compared with placebo or standard medications. Additional randomized and controlled trials are needed.