• Herbal Formula Science
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• v.24 no.1
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• pp.31-43
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• 2016

Objectives Based on related literature, cold and heat, deficiency and excess, true and false, and actually used formulas, paradoxical treatments presented in the 『Plain Questions of Inner Canon of Yellow Emperor』 including ‘treating pseudo-heat symptoms and real cold syndrome with cold herbs, treating pseudo-heat symptoms and real cold syndrome with cold herbs’ were analyzed.Methods Out of literature, paradoxical treatment related classics and papers were investigated and analyzed. Among diseases and syndromes, real cold syndrome with pseudo-heat symptoms, real heat syndrome with pseudo-cold symptoms, real deficiency syndrome with pseudo-excess symptoms, and real excess syndrome with pseudo-deficiency symptoms were reviewed. Among formulas, typical examples of the above mentioned paradoxical treatments were used as examples to analyze paradoxical treatments.Results Treating pseudo-heat symptoms and real cold syndrome with cold herbs is a method that uses herbs with cool and cold nature to treat real cold syndrome with pseudo-heat symptoms and Tongmaeksayeokgajeodamjeuptang is suitable for this method. Treating pseudo-cold symptoms and real heat syndrome with hot herbs is a method that uses herbs with warm and hot nature to treat real heat syndrome with pseudo-cold symptoms and Baekhogainsamtang is suitable for this method.Conclusions Based on the related literature, cold and heat, deficiency and excess, true and false, and actually used formulas examined as mentioned above, the paradoxical treatments presented in the 『Plain Questions of Inner Canon of Yellow Emperor』 are thought to be reasonable paradoxical treatments that fit the diseases and syndromes that actually appeared in our bodies.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.6
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• pp.1410-1415
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• 2008

Acupuncture and herbal treatment are based on diagnosis of cold and heat pattern in Traditional Korean Medicine. This diagnosis is accomplished through pulse, tongue and question examination, which are not objective. Quantification and objectification of this diagnosis process are required for efficacious treatment and traditional medicine development. In this study, we developed the cold-heat pattern questionnaire for this purpose. Seventy nine patients who visited oriental medical hospital were included in this study. The cold-heat pattern questionnaire was composed of many questions about patient's physical condition, which were derived from The Traditional Oriental Medical Literature with Delphi Technique. Patients filled out the cold-heat pattern questionnaire by themselves. Diagnosis of cold and heat pattern are conducted separately by oriental medical doctors with more than 5 years' clinical experience. Various physical condition factors were derived for the cold-heat pattern questionnaire. (Preference temperature, Body temperature, Pain type, Face color, Urine, Stool and secretion features) Each cold and heat symptoms group acquired internal consistency. (Cronbach's ${\alpha}$ : Cold - 0.605, Heat - 0.722) There were significant associations between doctor's diagnosis and cold symptoms in 'Aversion to cold', 'Desire for heat', 'Pale face', 'Loose stools'. (p-value < 0.05) There were significant associations between doctor's diagnosis and heat symptoms in 'Desire for cold', 'Body feverishness', 'Thirst'. (p-value < 0.05) The internal consistency results suggest that the cold-heat pattern questionnaire assured reliability. Besides, these results showed that cold-heat symptoms are apt to appear together with, and this can be indirect evidence that diagnosis of cold-heat pattern is valuable for comprehension about disease pattern. Moreover, respective symptoms of cold-heat pattern showed different significance with doctor's diagnosis. Consequently these significant symptoms can be more considered for comprehension of cold-heat pattern.

• Journal of Physiology & Pathology in Korean Medicine
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• v.30 no.2
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• pp.116-123
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• 2016

This study was performed to develop questionnaire of cold-heat pattern identification(PI) based on usual symptoms for general people, and we analyzed reliability of the questionnaire. We reviewed cold-heat PI questionnaire of advanced research and selected twenty-three items through three time experts meeting. Three hundred and fifty nine healthy subjects were joined in this study. As a results, Cronbach's α of cold-heat PI questionnaire was 0.79 and 0.83. According to the factor analysis about fifteen-chosen cold-heat PI questionnaires, each cold-heat consisted of two factors and each Convergence was 56.46% and 65.93%. Intra-class Correlation Coefficient was 0.67-0.83. Based on the median of samples of primary source, we classified subjects into four category as Cold, Heat, No Cold-Heat, and Cold-heat complex. We examined agreement of diagnosis and coefficient of kappa, and agreement rate of diagnosis was 64.2%, and coefficient of kappa was 0.51. Based on research result, we expect that validity study about questionnaire of cold-heat PI based on usual symptoms will be continued, and hope to be used as subsidiary diagnosis in clinical practice.

• The Journal of Korean Obstetrics and Gynecology
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• v.25 no.4
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• pp.27-37
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• 2012

Purpose: Dysmenorrhea is mostly depending on the causative factor, which usually falls under the categories of Cold and Heat pattern in traditional Oriental medical theories and diagnosis. Thus, we investigated menstruation symptom and sign related to dysmenorrhea and verified the validity of Cold and Heat pattern identification. Methods: We investigated menstruation symptom and sign related to dysmenorrhea in total 14 gynecology-medical books including ${\ll}$Exemplar Of Korean Medicine (Dongui Bogam)${\gg}$ and whole body symptom and sign identifying Cold and Heat pattern at the same time. A survey based on this investigation was carried out targeting women of childbearing age. Results: According to 14 gynecology-medical books, polymenorrhea is relevant to Heat pattern, oligomenorrhea to Cold pattern and darkness of menstrual blood is relevant to Heat pattern. Among the total of 343 womens, 196 subjects suffered from dysmenorrhea. The number of dysmenorrhea with polymenorrhea(Heat pattern) was 6 person, with oligomenorrhea(Cold pattern) was 27 person. And the number of dysmenorrhea with darkness of menstrual blood(Heat pattern) was 39 person. As the result of checking correlations of menstrual symptom scores and whole body symptom scores, there was no significance of Cold and Heat pattern between menstrual symptoms and whole body symptoms. Conclusions: The results suggest that the period of menstrual cycle and the color of menstrual blood provides some informations of Cold and Heat pattern identification. But considering with other whole body symptom and sign is needed for more precise result.

• Journal of Sasang Constitutional Medicine
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• v.17 no.3
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• pp.150-155
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• 2005

1. Objectives This case is aimed to verify the relation of Soeurnin Mang-yang Syndrome and Cold Syndrome with pseudo-heat syndrome. 2. Methods The patient has high fever, general body sweating, thirst and constipitation is diagnosed as Soeumin Mang-yang Syndrome. Mang-yang Syndrome one of the symptoms in the Exterior Febrile Disease induced from the Kidney affected by Heat in Soeumin(少陰人) marked by spontaneous sweating and fever with chills. This syndrome is similar to Cold syndrome with pseudo-heat symptoms in general symptoms and pathologic process. Therefore, We medicate Doksampalmul-tang to this patient who diagnosed as Soeumin Mang-yang Syndrome. 3. Results and Conclusions The symptoms that the patient has fever, sweating, thirst and constipitation are solved after the medication. This means recovery of Yang-Energy in Kidney and the spleen.

• Journal of Society of Preventive Korean Medicine
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• v.26 no.1
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• pp.59-74
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• 2022

Objectives : Evidence supporting the cold-heat symptom and sasang constitution type, which are diagnostic items of traditional Korean medicine, is needed to manage sleep disturbances, which is a typical symptom of mibyeong (subhealth). This study examined the association between each cold-heat symptom and sleep disturbances according to each sasang constitution type. Methods : This research was a cross-sectional study of 5,793 subjects from the Korean Medicine Data Center (KDC) community cohort survey. The association between each cold-heat symptom and sleep disturbances was analyzed by logistic regression analysis adjusted for several demographic variables. Subgroup analysis was then performed for each type of sasang constitution. Results : The soeum and soyang types were 1.53 and 1.26 times more likely to have sleep disturbances than the taeum type. Sleep disturbances were associated with 'coldness of the abdomen', 'watery mouth' in the cold domain items, and 'body feverishness', 'flushed face and eye', 'thirst', and 'scanty dark urine' in the heat domain items. The soeum and soyang types were 1.55 and 1.39 times more likely to sleep less than five hours per night than the taeeum type. In addition, the associations of those showed a different pattern for each sasang constitution type. Conclusions : Sleep disturbances are associated with specific cold-heat symptoms, and the associated cold-heat symptoms differ according to the sasang constitution type. These results may help traditional medicine specialists select customized interventions for patients with sleep disturbances.

• Journal of Sasang Constitutional Medicine
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• v.33 no.1
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• pp.1-21
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• 2021

Objective The purpose of this study was to examine the correlation between the Cold-damage Six-meridian disease of Qibo (岐伯六經病證) and Sasang Constitutional Symptomatology (四象體質病證), presented in Discourse on the Origin of Eastern Medicine (醫源論) of Longevity and Life Preservation in Eastern Medicine (Donguisusebowon, 東醫壽世保元). Method The process of development from Cold-damage Six-meridian disease of Qibo (岐伯六經病證) to Six Meridians Physical Symptoms and Medicines (六經形證用藥) in the chapter Cold(寒門) of the Treasure Mirror of Eastern Medicine (Donguibogam, 東醫寶鑑) was investigated. And the correlation between Six Meridians Physical Symptoms and Medicines (六經形證用藥) and Sasang Constitutional Symptomatology (四象體質病證) was considered. Results and Conclusions 1. The Cold-damage Six-meridian disease of Qibo (岐伯六經病證) in the chapter Heat Treatise (熱論篇) of Basic Questions (素問) had evolved into Six Meridians Physical Symptoms and Medicines (六經形證用藥) in the chapter Cold(寒門) of the Treasure Mirror of Eastern Medicine (Donguibogam, 東醫寶鑑) through Book for Life Saving (Huorenshu, 活人書), a work of Zhu Gong (朱肱), Six Books on Cold Damage disease (Shanghanliushu, 傷寒六書), a work of Tao Hua (陶華) and Introduction to Medicine (YixueRumen, 醫學入門), a work of Li Chan (李梴). 2. The correlation between the Cold-damage Six-meridian disease of Qibo (岐伯六經病證) and Sasang Constitutional Symptomatology (四象體質病證) can be analyzed and understood through Six Meridians Physical Symptoms and Medicines (六經形證用藥) in the chapter Cold(寒門) of the Treasure Mirror of Eastern Medicine (Donguibogam, 東醫寶鑑). 3. Greater Yang meridian disease of Qibo (岐伯) is related to Soyangin early stage of Lesser-Yang Wind-Injury symptomatology and Soyangin early stage of Chest-Heat symptomatology, Yang Brightness meridian disease and Greater Yin meridian disease to Taeeumin Liver-Heat symptomatology, Lesser Yin meridian disease to Soyangin Chest-Heat symptomatology, Lesser Yang meridian disease to Soyangin early stage of Lesser-Yang Wind-Injury symptomatology and Reverting Yin meridian disease to Soeumin Reverting Yin symptomatology of Greater Yang disease.

• Journal of Physiology & Pathology in Korean Medicine
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• v.30 no.6
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• pp.466-473
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• 2016

This study intended to find out the most substantial items in cold and heat pattern identification(CHPI) questionnaire based on usual symptoms through CHPI diagnosis and evaluation by experts. 120 participants, faculties of OO university, filled out CHPI questionnaire based on usual symptoms by the way of self-reporting. Then 2 Korean Medicine doctors independently diagnosed them whether they belonged to cold pattern identification(PI) or heat PI, and scored the result of it. Pearson correlation of 2 experts was 0.649 in cold PI and 0.605 in heat PI. Agreement was 75.8%(Kappa value 0.516) in cold PI and 74.2%(Kappa value 0.465) in heat PI. Pearson correlation of 2 experts was 0.649 in cold PI and 0.605 in heat PI. Agreement between two experts was 75.8%(Kappa value 0.516) in cold PI and 74.2%(Kappa value 0.465) in heat PI. Items of high correlation with experts' evaluation followed next: "do not usually like the cold", "usually like the warm", "usually feel cold" in cold PI and "do not usually like the hot", "usually feel hot", "usually feel burning sensation in the body" in heat PI. We could infer from that facts that experts give weight on 'subjective feeling of cold or heat in participants body' and 'preference on sensation of cold and heat'. We also expect this study to be an epidemiological foundation to disclose correlation between usual CHPI and diseases.

• Journal of Sasang Constitutional Medicine
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• v.23 no.2
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• pp.240-253
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• 2011

1. Objectives: The purpose of this study was to survey the Original symptoms(素證) of Soyangin's and to compare the tendency of their symptoms between Soyangin Heat-related diarrhea accompanied by headache(身熱頭痛亡陰證) and Soyangin Cold-related diarrhea accompanied by abdominal pain(身寒腹痛亡陰證). 2. Methods: We recruited 56 Soyangin subjects in the Korean Medicine clinic and researched their original symptoms. Subjects were diagnosed by the Sasang Constitutional specialists and Sasang Constitutional Medication. Subjects were two groups, confirmed to Soyangin Heat-related diarrhea accompanied by headache and Soyangin Cold-related diarrhea accompanied by abdominal pain. All subjects answered the questionnaire about their Original symptoms. We found the differences between 2 groups using the Independent-Samples T-test. Analysis was conducted using SPSS 12.0 for Korean. 3. Results and Conclusions: In Original symptoms, Tendency of overeating(p=0.01), Condition of digestion(p=0.04), Perspiration after exercise (p=0.02), Usual perspiration(p=0.00), Tiredness after perspiration(p=0.05) Cold intolerance on extremities(p=0.04), General edema(p=0.01) etc. are different between 2 groups. We found the differences of heat and cold in symptoms between two Soyangin syndromes.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.2
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• pp.532-538
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• 2007

In order to establish the standard symptoms in men and women and highly frequent symptoms(HFS) of Phlegm(痰) Blood Stasis(血於) Cold(寒) Heat(熱) Dryness(濕) pathogenesis(病機), 969 questionnaires were analyzed through Cronbach alpha value and Pearson's correlative efficient. The Cronbach ${\alpha}$ value of each pathogensesis was Phlegm(0.83500)${\cdot}$Cold(0.823272)${\cdot}$Heat(0.816344)${\cdot}$Dampness(0.760292)${\cdot}$Blood Stasis(0.692551)${\cdot}$Dryness(0.672783) respectively. Through this study of frequency number of symptoms, followings were found that the physiological differences of men and women made some differences of main symptoms in each pathogenesis, and the differences of several clinical symptoms in a pathogenesis were resulted from the difference of specimens between textbook and this study.