• The Korean Journal of Pain
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• 제29권4호
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• pp.266-269
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• 2016

The superficial peroneal nerve is vulnerable to damage from ankle sprain injuries and fractures as well as surgery to this region. And it is also one of the most commonly involved nerves in complex regional pain syndrome type II in the foot and ankle region. We report two cases of ultrasound-guided pulsed radiofrequency treatment of superficial peroneal nerve for reduction of allodynia in CRPS patients.

• 동의생리병리학회지
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• 제23권3호
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• pp.678-684
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• 2009

It was reported that Dipsaci Radix has decrease pain effect on the Complex Region Pain Syndrome(CRPS). the CRPS was induced by unilateral loose occlusion in 4 part of the sciatic nerve of the rats. For the fingding significantly change on CRPS rats were divided into 4 different experimental groups. and each groups were induced CRPS. Experimental group I (control group; n=15), experimental group II (100 mg/kg Dipsaci Radix dieted rats; n=15), experimental group III (300 mg/kg Dipsaci Radix dieted rats; n=15), and experimental group IV(500 mg/kg Dipsaci Radix dieted rats; n=15). The study of Dipsaci Radix concentration was that foot withdrawal threshold to the thermal stimuli(Hot plate test), foot withdrawal threshold to the mechanical stimuli(von Frey's filament) and immunohistochemistry staining that were substance P. Hot plate test and von Frey Filament were increase in experimental group II, III, IV than group I, especially group III was most significantly change than group II and IV in post-hoc(Duncan's multiple range). and In immunohistochemistry observation; group I showed increase in the group II, III, IV. especially group III had the minimal level of the substance P expression while the experimental group II, III. These results suggested that the Dipsaci Radix dieted made the decrease of pain in CRPS.

• The Korean Journal of Pain
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• 제19권2호
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• pp.223-227
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• 2006

Complex regional pain syndrome (CRPS) is clinically characterized by pain, abnormal regulation of blood flow and sweating, edema of skin and subcutaneous tissues, sensory and motor disturbances, and trophic changes of the skin. A 21-year-old man was suffering from pain and swelling in his right hand and forearm. His arm had been in splints for 3 weeks following an extension injury of the right fingers and wrist, with the pain having developed 2 weeks after the splinting. He was treated with various nerve blocks including continuous epidural infusion, thoracic sympathetic block and peripheral nerve blocks, and squeezing his edematous region under general anesthesia as well as intravenous lidocaine and ketamine infusions. However, all of the performed treatments had no effect on the patient's pain or hand swelling. As a next line therapy, spinal cord stimulation should be considered because of intractable severe pain and swelling to almost all other modalities of therapy. We therefore performed an early intervention of spinal cord stimulation for the patient with refractory CRPS type I 5 months after the onset of pain and have got an excellent result.

• The Korean Journal of Pain
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• 제34권3호
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• pp.322-331
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• 2021

Background: The present study employed National Health Insurance Data to explore complex regional pain syndrome (CRPS) updated epidemiology in a Korean context. Methods: A CRPS cohort for the period 2009-2016 was created based on Korean Standard Classification of Diseases codes alongside the national registry. The general CRPS incidence rate and the yearly incidence rate trend for every CRPS type were respectively the primary and secondary outcomes. Among the analyzed risk factors were age, sex, region, and hospital level for the yearly trend of the incidence rate for every CRPS. Statistical analysis was performed via the chi-square test and the linear and logistic linear regression tests. Results: Over the research period, the number of registered patients was 122,210. The general CRPS incidence rate was 15.83 per 100,000, with 19.5 for type 1 and 12.1 for type 2. The condition exhibited a declining trend according to its overall occurrence, particularly in the case of type 2 (P < 0.001). On the other hand, registration was more pervasive among type 1 compared to type 2 patients (61.7% vs. 38.3%), while both types affected female individuals to a greater extent. Regarding age, individuals older than 60 years of age were associated with the highest prevalence in both types, regardless of sex (P < 0.001). Conclusions: CRPS displayed an overall incidence of 15.83 per 100,000 in Korea and a declining trend for every age group which showed a negative association with the aging shift phenomenon.

• The Korean Journal of Pain
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• 제26권3호
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• pp.295-298
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• 2013

Glomus tumors are benign tumors that account for 1% to 5% of all soft tissue tumors of the hand and are characterized by a triad of sensitivity to cold, localized tenderness and severe paroxysmal pain. Paroxysmal pain is a symptom common not only in glomus tumors but also in CRPS, and the hand is one of the commonly affected sites in patients with both glomus tumors and CRPS. Therefore, it is not easy to clinically diagnose glomus tumors superimposed on already affected region of CRPS patients. We report a case of glomus tumor concomitantly originating with CRPS at the hand.

• 대한핵의학회지
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• 제25권1호
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• pp.81-86
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• 1991

Reflex sympathetic dystrophy syndrome (RSDS), known also as Sudeck's atrophy, is an uncommon disorder recognized by its distinctive symptom complex consisting of pain and tenderness, vasomotor instability, swelling, and dystrophic skin changes and radiologic changes. The present study has been carried out to prospectively establish scintigraphic diagnostic criteria for RSDS using three-phase radionuclide bone scintigraphy (TPBS). In addition, the usefulness in the evaluation of treatment of RSDS was assessed. Patients included were 6 men and 7 women with the age ranging from 25 to 63 years (average 47 years). Diagnosis was based on typical clinical symptoms and signs as described above. Associated clinical conditions in these patients were cerebral infarction (4 patients), lung cancer (2 patients), trauma (1 patient), lymphoma (1 patient), and unknown cause (5 patients). All patients showed diffuse radionuclide accumulation in juxtaarticular region on the delayed static image and 11 patients showed diffusely increased activities also on scintiangiogram and blood-pool image. Fillow-up TPBS after corticosteroid therapy in 4 patients revealed near normal return of abnormal radionuclide accumulations in the affected hand. TPBS is an useful test for the diagnosis of as well as the evaluation of the therapeutic effects of RSDS.

• 동국한의학연구소논문집
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• 제8권2호
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• pp.115-129
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• 2000

동물성(動物性) 지방섭취량(脂肪攝取量)의 증가(增加), 운동부족(運動不足), 비만(肥滿), 스트레스의 가중(加重), 고령화(高齡化)의 증가(增加) 등(等)의 원인(原因)으로 순환기계질환(循環器系疾患)의 발병률(發病率)이 증가(增加)하고 있으며, 이러한 순환기계질환(循環器系疾患)의 위험인자(危險因子)로서 혈전증(血栓症)이 중요(重要)하게 대두되고 있다. 특히 최근 문제시되고 있는 협심증(狹心症)이나 심근경새(心筋梗塞)등의 허혈성(虛血性) 심질환(心疾患)은 혈소판응집(血小板凝集)에 의해 일어나는 혈전형성(血栓形成)에 기인(起因)하고 있다. 한의학(韓醫學)에서 혈전증(血栓症)은 어혈(瘀血)의 범주(範疇)에 속(屬)하며, 어혈(瘀血)은 각종 병리적(病理的) 원인(原因)에 의해 발생한 전신성(全身性) 또는 국소성(局所性)의 혈액순환(血液循環) 장애(障碍) 또는 혈류정체(血流停滯)와 그에 수반되는 일련의 증후(症候)를 나타내며, 경계정충, 고창(鼓脹), 적취(積聚), 미하, 전광(癲狂), 중풍등(中風等)의 발병원인(發病原因)이 된다. 또한 어혈(瘀血)에 의한 각종 증후(症候)에는 활혈거어제(活血祛瘀劑) 또는 구어혈제(驅瘀血劑)등이 사용되고 있다. 본(本) 연구(硏究)에서는 한의학(韓醫學)에서 어혈증(瘀血症)으로 야기(惹起)되는 여러 가지 증상(症狀)의 개선에 사용되는 구어혈제(驅瘀血劑)들의 혈소판응집(血小板凝集)에 미치는 영향을 검색하기 위하여 계지복령환(Geijibokryunghwan; GBH) 및 그 구성약물(構成藥物)을 사용(使用)하였다. 계지복령환은 "금궤요략" 에 있는 방(方)으로써 거사부상정(祛邪不傷正)하고 조기한열(調氣寒熱)하여 예로부터 구어혈제(驅瘀血劑)로 사용되어 왔다. 이에 계지복령환 및 그 구성약제(構成藥劑)의 ADP, AA 또는 collagen으로 유도되는 혈소판응집(血小板凝集)에 대하여 억제효과(抑制效果)를 탐색(探索)한 결과(結果), 계지복령환 및 개별(個別) 구성약물(構成藥物)의 혈소판응집억제작용(血小板凝集抑制作用)을 확인하였고, 혈소판응집(血小板凝集)으로 야기(惹起)되는 혈전증(血栓症)등에 계지복령환 및 개별(個別) 구성약물(構成藥物)은 매우 임상실험적(臨床實驗的) 응용가치(應用價値)가 있는 것으로 생각되었다.