• Journal of Ginseng Research
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• v.41 no.4
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• pp.450-455
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• 2017

Chronic liver disease, one of the most common diseases, typically arises from nonalcoholic fatty liver disease, alcoholic liver disease, chronic viral hepatitis, or hepatocellular carcinoma. Therefore, there is a pressing need for improved treatment strategies. Korean Red Ginseng has been known to have positive effects on liver disease and liver function. In this paper, we summarize the current knowledge on the beneficial effects of Korean Red Ginseng on chronic liver disease, a condition encompassing nonalcoholic fatty liver disease, alcoholic liver disease, chronic viral hepatitis, and hepatocellular carcinoma, as supported by experimental evaluation and clinical investigation.

• Journal of Nutrition and Health
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• v.30 no.1
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• pp.48-60
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• 1997

The purpose of this study was to evaluate alcohol consumption and nutritional status in patients with alcoholic liver disease. The subjects were 80 patients with alcoholic liver cirrhosis and 12 patients with alcoholic fatty liver. Also 57 alcoholics without liver disease, 32 patients with viral liver cirrhosis and 194 normal men were included as control groups. Data on anthropometric index, socioeconomic status, alcohol consumption, dietary habits and dietary intakes were collected by individual interview. Alcoholic liver disease group had significantly lower triceps skinfold thickness and mid-uppr-arm circumferences than other groups. Socioeconomic status of alcholoci subjects was middle class or lower than that. The amount, duration and frequency of alcohol consumption were significantly higher and the quality of side dishes consumed with alcoholic beverage was significantly poorer in patients with alcoholic liver cirrhosis than others. Patients with alchololic liver disease ingested approximately 40% of daily caloric intake as alcohol and all alcoholic subjects had lower average intakes of protein, carbohydrates, fat, vitamins and minerals as compared with Korean adult average intakes. The results suggest that alcohol and poor dietary intake could cause malnutrition and might be two of the important risk factors to develop alcoholic liver disease in alcoholics. But other factors like genetic and immunological factors should be also considered in elucidating the causes of alcoholic liver disease. An extensive nutritional education should be emphasized for alcohol consuming population to prevent development of alcoholic liver disease.

• The Journal of Internal Korean Medicine
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• v.21 no.2
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• pp.349-354
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• 2000

Objective : The studies on liver effect in administration of western medicine have been well-established so far, but the studies on liver effect in administration or herbal medicine haven't been made. To make things worse, people who have liver disease generally believe that taking a herbal medicine is not useful to take care or their disease and even think it can cause liver disease. But this belief is not verified at all. And some doctor claim that herbal medicine is good to cure liver disease. So those various assertion makes patients to feel confuse about taking a herbal medicine. so we feel the need to study about how taking herb medicine affect to liver disease patient. Methods : First we chose the 12 patient who seems to have the liver disease on the index of biochemistry test and we administrate the herbal medicine and after several day or weeks we recheck the biochemistry test. Results : Through the this method, we find the positive effect of taking herbal medicine on the patients who have the liver disease. Conclusions : Our results give no evidence that herbal medicine is harmful for liver disease. We need to study more about this.

• Journal of Sasang Constitutional Medicine
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• v.27 no.1
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• pp.57-70
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• 2015

Objectives This research was performed to present Clinical Practice Guideline(CPG) for Taeeumin Disease of Sasang Constitutional Medicine(SCM): Liver Heat-based Interior Heat (Gansuyeol-liyeol) disease. This CPG was developed by the national-wide experts committee consisting of SCM professors. Methods First, it was performed that search and collection of literature related to SCM such as "Dongeuisusebowon", Textbook of SCM, Clinical Guidebook of SCM and fundamental researches to standardize the diagnosis of Sasang Constitutional Medicine. And journal search related to clinical trials and case studies concerning SCM was performed domestic and overseas. Finally, 12 articles were selected and included in CPG for Liver Heat-based Interior Heat (Gansuyeol-liyeol) disease in Taeeumin Disease. Experts consensus was drawn through several meetings. Results & Conclusions CPG of Liver Heat-based Interior Heat (Gansuyeol-liyeol) disease in Taeeumin Disease include classification, definition and standard symptoms of each pattern. Liver Heat-based Interior Heat (Gansuyeol-liyeol) disease is classified into Liver-Heat (Ganyeol) symptomatology and Liver-Heat Lung-Dry (Ganyeol-paeJo) symptomatology. Depending on the severity of Liver Heat, Liver-Heat (Ganyeol) symptomatology is classified into mild pattern and moderate pattern. Mild pattern contains 1 disease, namely, Liver-Heat (Ganyeol) initial pattern. Moderate pattern classified into advanced pattern and intense pattern. Depending on the severity of the Lung-Dry, Liver-Heat Lung-Dry (Ganyeol-paeJo) symptomatology is classified into severe pattern and critical pattern. Severe pattern is classified into Dry-Heat (Joyeol) pattern and Dry-Heat (Joyeol) advanced pattern. Critical pattern contains 1 disease, namely, Dry-Heat (Joyeol) intense pattern (Eumhyeol-mogal yeolda pattern).

• The Journal of the Korean life insurance medical association
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• v.3 no.1
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• pp.142-148
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• 1986

Liver is an oragan which has various functions. For this functions in liver disease change variously, many methods of examination of them are invented. Each liver disease impairs these functions diversly rather than uniformly, thus it is possible to differentiate each disease by using various methods of testing it. Liver has high reproductive capacity and despite partial impairment of its function localized disease may not show any abnormality in liver function test due to compensation of remaining intact tissue of the liver. Thus the result of liver function test should be interpreted under adequate clinical investigation with other test, not depending on the liver function test only. This thesis deals with the composition, distribution in living body and clinical significance of liberating enzyme, GOT, GPT, and LDH which are included in serum enzyme that show abnormality in liver disease.

• The Korean Journal of Nuclear Medicine
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• v.21 no.2
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• pp.199-205
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• 1987

The fact there are increase of intrapulmonary arterioveneous shunt amount in the liver cirrhosis patient has been known since 1950. And the method of shunt amount calculation by radionuclide method using $^{99m}Tc-MAA$ was introduced in the middle of 1970. We measured intrapulmonary shunt amount by means of perfusion lung scan using $^{99m}Tc-MAA$ in the various type of liver diseases especially in chronic liver diseases and acute liver disease. The results were as followed. 1) The amount of arteriovenous intrapulmonary shunt in the total case of liver disease was $9.3{\pm}3.9%$, and that of in the control group was $4.6{\pm}2.1%$. 2) The amount of arteriovenous intrapulmonary shunt in the chronic liver disease was $10.8{\pm}4.4%$, and that of in the acute liver disease was $7.2{\pm}2.8%$. We observed significant differences between normal control group and liver disease group, and between chronic liver disease group and acute liver disease group in the amount of shunt by the nucleolide method.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.4
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• pp.630-636
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• 2002

After The Yellow Emperor's Canon of Internal Medicine, The text researches of pathologic change to the liver disease concluded the next, 1, The category of liver-disease(肝病) include the Symptoms of abnormality due to vital energy and blood motion, emotion and intention, muscular and reproductive function, and legions around descending liver channel. 2. In the theory that Liver-Yang energy(肝陽氣) is always overproducing, Liver-Yin blood(肝陰血) is always lacking, pathologic characteristics for liver disease is functional change of malfunction of the use of body(體用失調), So nourishing the liver and kidney is used for the principal aspects of a disease. regulating and calm the liver is used for the secondary aspects of a disease as the treatment plan, 3. If malfunctioning of the functions of dispersion and discharge(疏泄), Iiver-energy(肝氣) is becoming degected, So overproduct and overflow of ascent and exhalation of liver-yang(肝陽) is becoming blood are ascending following energy. complete usage of Yin-blood(陰血) is responsible for some kinds of mass formed by blood stasis in the early stage of pathogenesis of liver disease syndrome of the energy system as the progession of disease extravasated blood is forming. the pathologic characteristics is appeared loss of control of the vital energy and blood(體用失調) at the liver disease. 4. Sthenia-syndrome of liver(肝實證) and liver-heat syndrome(肝熱證) is appered that overproducing and overflow of dispersion(疏泄太過) and discharge is responsible for overfunctioning of liver disease or some kinds of heat syndrome such as liver fire(肝火), Sthenia of liver-yang(肝陽上亢), the syndromes of sthenic liver heat(肝實熱) are appered. deficiency of the liver(肝虛證) and cold syndrome of liver(肝寒證) is classified pathologic characteristics of cold and heat, deficiency and excess that regression of sensory, motor, mental due to lack of dispersion and discharge(疏泄不及), or intruding of the cold miasma, are degected. 5. The liver is close relation of physiologic function and internal organ such as spleen, stomach, lung, heart, kidney, gall bladder by the meridian channels, because of property of wind Zang, rapid progession is classified by phthologic charateristics.

• The Korean Journal of Nuclear Medicine
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• v.16 no.1
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• pp.63-72
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• 1982

Hepatoscintigram has been a useful diagnostic method for the liver diseases since 1953, but reasonable diagnostic criteria for parenchymal liver diseases are not yet accurately established. For the purpose of searching for more advanced diagnostic criteria for various types of live disease by the liver scan, a retrospective study was made of 272 cases who underwent both hepatoscintigram with 198 Au colloid and liver biopsy in Hanynag University Hospital from Jan., 1978 to Dec., 1981. The results were as follows: 1. Fuzzy margin (irregular indentation of the liver margin) in the hepatoscintigram was noted in 226 cases (97.79%). 2. Of 35 cases with fuzzy margin only, 28 cases (80%) revealed mild parenchymal liver disease, such as acute hepatitis or chronic persistent hepatitis by the liver biopsy. 3. Mottling change (209 cases) was always accompanied by fuzzy margin except only one case, and 31 cases (86.1%) of fuzzy and mottling cases (36 cases) showed mild parenchymal liver disease. 4. Configuration change (193 cases) was usually accompanied with other changes and espicially 104 cases had configuration change with fuzzy and mottling changes. 73 cases (88.44%) of 86 cases with severe configuration change revealed advanced parenchymal liver disease on biopsy. If liver scan showed mild configuration change, we could not decide the type of liver disease only liver scan, and so further studies are needed. 5. Splenic uptake was noted in 34 cases (40.48%) of 84 cases with advanced parenchymal liver disease, and the degree of splenic uptake was for the most part morderate or severe; whereas splenic uptake was noted in 18 cases (16.51%) of the mild parenchymal liver disease (109 cases), and the degree of splenic uptake was largely mild.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.19 no.3
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• pp.159-171
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• 2015

Objectives: Lately, non alcoholic fatty liver patients are increasing rapidly and the average age of patients are getting younger. Non alcoholic fatty liver often represents asymptomatic and korean pattern diagnosis is difficult to implement without symptoms. This study aimed to analyze interrelationship between non alcoholic fatty liver disease and Injinho-tang. Methods The AHP is a systematic procedure for analyzing the elements of any problem hierarchically. Based on survey of expertise, as series of pairwise comparison judgements is performed to evaluate the various elements in the hierarchy. We are expected to use the AHP analysis that would apply to oriental doctor's diagnostic process analysis. Results and conclusion Non-alcoholic fatty liver disease induced complex causes of the metabolic syndrome. Injinho-tang has been widely used disease that causes jaundice and liver biliary disease. According to AHP analysis, LFT is the most important facor in choosing Injinho-tang on non alcoholic fatty liver disease. BMI and body composition by bioelectrical impedance analysis are the next important factors. Personal hot temper also gives a big impact on choicing Injinho-tang on non alcoholic fatty liver disease.

• The Korean Journal of Health Service Management
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• v.7 no.3
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• pp.261-273
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• 2013

The purpose of this study is a chronic liver disease that affects the drinking behavior is to identify the factors. The subjects of the study was diagnosed with chronic liver disease outpatient visit were studied in 120 patients. The collected data were analyzed by using SPSS WIN 18.0. Drinking behavior of chronic liver disease to determine the factors influencing the results of the multiple regression analysis, the regression model was found to be significant(F=8.58, p<.001), drinking behavior of chronic liver disease a major contributor to the drinking habits(${\beta}$ = -.29, p = .004)was found in, followed by drinking motives(${\beta}$ = .20, p = .044), drinking refusal self-efficacy(${\beta}$ = -.17, p = .037), after which the diagnosis of the disease(${\beta}$ = .15, p = .041), respectively. These variables showed explanatory power of 44.1%. Drinking behavior is a serious health problem in patients with chronic liver disease. The factors that influence drinking behavior by considering the management of chronic liver disease drinking continued to provide information and education is needed abstinence.