• Journal of Applied Biological Chemistry
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• v.59 no.1
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• pp.5-7
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• 2016

One of oriental medicinal plants, Potentilla chinensis, has been used for anti-inflammation, hemostatic, decryption, and antipyretic. Especially, a root of Potentilla chinensis was used as important material for oriental medication. Although several kinds of bioactive component of Potentilla chinensis extract from stems and leaves were identified, the major component of Potentilla chinensis from roots is not well established. In this study, the root of Potentilla chinensis was extracted in different solvent system and analyzed by high performance liquid chromatography (HPLC). According to HPLC analysis, a major component was isolated and its physicochemical properties were evaluated by mass spectrometry and nuclear magnetic resonance. Based on these results, isolated compound was identified as 2,3,8-Tri-O-methylellagic acid. And quantification of 2,3,8-Tri-O-methylellagic acid with different extraction solvent system was performed for industrial application.

• Korean Journal of Pharmacognosy
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• v.25 no.2
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• pp.178-187
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• 1994

Korean folk medicine 'Jin Hae Cho' has been used as a remedy for neuralgia and an invigorating drug after a childbirth in Korea. The botanical origin of the crude drug has been no pharmacognostical confirmation on it. To clarify the botanical origin of 'Jin Hae Cho', studied on the morphological and anatomical characteristics of the roots of Potentilla species growing wild in Korea i.e. Potentilla chinensis Ser., P. cryptotaeniae Maxim., P. dickinsii Fr. et Sav., P. discolor Bunge, P. fragarioides L. var. major Maxim., P. freyniana Bornm., P. kleiniana Wight et Arnott, P. paradoxa Nutt., P. yokusaiana Makino and 'Jin Hae Cho' from Korea on Korean market. As a result, it was made clear that 'Jin Hae Cho' from Korea was derived from the roots of Potentilla chinensis Ser. and Potentilla discolor Bunge.

• YAKHAK HOEJI
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• v.33 no.6
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• pp.377-379
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• 1989

The methylated compound of ellagic acid was isolated from Potentilla chinensis (Rosaceae). The isolated compound was 3, 3', 4-tri-O-methylellagic acid, [2, 3, 7-trimethoxy-8-hydroxy[1] benzopyrano-[5, 4, 3, cde][1] benzopyran-5, 10-dione], $C_{17}H_{12}O_8$, m.p. $293-295^{\circ}C$. The isolation of trimethylellagic acid was conducted by the column chromatography and the identification of the compound was carried out by the methods of IR, NMR and MS spectroscopy.

• Journal of Applied Biological Chemistry
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• v.59 no.1
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• pp.13-17
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• 2016

As natural plant-based industry has been expanded, the use of oriental medicinal plants as cosmeceutical material received a lot of attentions in the cosmetic industry. Among various medicinal plants, Potentilla chinensis have drawn interests for its biological effects. Although several attempts were tried to study its biological effect as medicinal plant, only limited results were reported to evaluate its biological effect as cosmeceutical material. In this study, we examined the possibility of root extract from Potentilla chinensis as a cosmeceutical material because the root part has been reported to have several kinds of health promoting effects. After extraction of roots, biological evaluation including anti-inflammation, anti-wrinkle, whitening effect and moisturizing effect was performed. As a result, the root extract showed remarkable biological activities through stimulating synthesis of elastin and aquaporin-3, and inhibiting melanin synthesis, cyclooxygenase-2 expression and expression of metallopeptidase-1.

• KSBB Journal
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• v.28 no.1
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• pp.13-17
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• 2013

In this study, we investigated the anti-inflammation effect of Potentilla chinensis (PC) on Raw264.7 macrophage cells. Ethanol extract of PC decreased the production of nitric oxide (NO) in LPS-stimulated RAW264.7 cells. Ethanol extract was fractioned by n-hexane, chloroform, ethyl acetate, n-butanol, water and each fraction was tested for inhibitory effects on inflammation. Among the sequential solvent fractions, PC chloroform extracts (50, 100, 300, and 500 ${\mu}g/mL$) significantly suppressed LPS-stimulated production of NO. During the entire experimental period, 200 and 300 ${\mu}g/mL$ of PC chloroform extracts had no cytotoxicity. LPS-induced NO and prostaglandin $E_2$ ($PGE_2$) production were inhibited by PC chloroform extracts up to 50% and 90% of these productions, respectively. PC chloroform extracts reduced the expression of iNOS and COX-2 gene. These results suggest that PC chloroform extracts exhibit strong effects of anti-inflammation and can be a potential candidate in the treatment of acute and chronic inflammatory diseases.

• Korean Journal of Pharmacognosy
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• v.35 no.3 s.138
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• pp.215-228
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• 2004

The Korean folk medicine 'Jin Hae Cho Ip' has been used as a remedy for neuralgia and as an invigorating drug after a childbirth, etc in Korea. With regard to the botanical origin of 'Jin Hae Cho Ip', several species of Potentilla (Rosaceae) has been refired, but no pharmacognostical study has yet been performed in this regard. To clarify the botanical origin of the 'Jin Hae Cho Ip', the morphological and anatomical characteristics of the leaflets and petioles of Potentilla and Sibbaldia species growing in Korea, such as P. chinensis, P. cryptotaeniae, P. dickinsii, P. discolor, P. fragarioides var. major, P. freyniana, P. kleiniana, P. matsumurae, P. paradoxa, and S. procumbens, were compared. As a result, it was found that 'Jin Hae Cho Ip' was composed of the leaves of P. Chinensis and P. discolor.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.6
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• pp.1444-1448
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• 2009

Potentilla chinensis Ser. (Rosaceae) has long been used for a remedy of diarrhea and inflammation in Korea. In this study, the anti-inflammatory effects of the Potentillae chinensis Herba water extract (PCX) was investigated in proteinase-activated receptor-2 (PAR2)-mediated rat paw edema. Paw edema was induced by injection of trypsin or trans-cinnamoyl-LIGRLO-$NH_2$ (tc-$NH_2$) into the hind paw of rats. PCX (10, 50, 100 and 200 mg/kg) was orally administered 1 h before the induction of inflammation. At doses of 50, 100 and 200 mg/kg, PCX showed significant inhibition on both change in paw volume and vascular permeability. PCX (100 mg/kg) significantly inhibited PAR2 agonists-induced myeloperoxidase (MPO) activity in paw tissue. These results indicate that PCX has an anti-inflammatory action in PAR2-mediated paw edema.

• Proceedings of the Korean Society of Crop Science Conference
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• 2006.04a
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• pp.600-601
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• 2006

• Journal of the Korean Society of Environmental Restoration Technology
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• v.6 no.1
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• pp.15-27
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• 2003

A method of conserving the vegetation at Mt. Chonggye was established to persue a practical management of the natural ecosystem by the vegetative composition analysis. As a result, the vegetation of surveyed areas was classified into two communities and four subcommunities in Mt. Chonggye. Potentilla fragarioides var. major community, known as the roadside plant community, distributed near trails under heavy human impacts. Potentilla fragarioides var. major community included two subcommunities : Digitaria sanguinalis-Ambrosia artemisiifolia var. elatior subcommunity and Rhus chinensis subcommunities. In these communiyies, there were many naturalized plant species such as Aster pilosus and Artemisia princeps var. orientalis, known as heliophilous plant. Results indicated that the vegetation had been affected by intensive human activities. It is necessary to control the naturalized plant species such as Aster pilosus for conservation of the ecosystem and nature in this area. Quercus mongolica community, a common coppice woodland in central Korea, was mostly distributed around mountain tops and ridges above 529 m altitute. In the valley where the forests well conserved, the Quercus mongolica community contained the Syneilesis aconitifolia-Hemerocallis lilioasphodelus subcommunity. On the other hand, Potentilla dickinsii subcommunity was dominated in dry rocky ridge areas. In these areas, however, the vegetation and forest soil was not properly managed for conservation.

• The Korean Journal of Ecology
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• v.11 no.2
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• pp.97-107
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• 1988

The forest vegetation occurring mainly at the mountain areas in periphery of Seoul were inversigated phyeosociologically. The granitic rocky outcrops are typical physiognomy on the study areas. The greater part of forests was the secondary vegetation to be disturbed by hyman impacts, because of being situated near the metropolis with a highly dense population. Four community types were largely differentiated by species composition. The representitive ones were the Quercus monogolica community and Pinus densiflora-Juniperus schinensis community, which are predominantly gorwing at the slopes above about 100m in altituse and the rocky ridges, respectively. The Betula chinensis-Potentilla dickinsii community at several single-peaks of windswept and the Zelkova serrata-Prunus padus community at stony valley are sporadically growing in a small area.