• Title/Summary/Keyword: pysiological activity

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Effect of Blood Glucose Levels and Lipid Metabolism on Streptozotocin-induced Diabetic Rats of Processed Sulfur with Cordyceps Militaris Mycelium (동충하초 균사체를 이용한 법제 유황이 STZ 유발 당뇨쥐의 혈당 및 지질대사에 미치는 영향)

  • Kim, Ki-Chul;Kim, Hae-Ja;Cho, Hwa-Eun;Choi, Yun-Hee;Lee, Ki-Nam;Chong, Myong-Soo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.1
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    • pp.144-149
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    • 2009
  • The purpose of this study was evaluated physiological activity of processed sulfur with Cordyceps militaris mycelium. Effect of blood glucose levels and lipid metabolism on streptozotocin-induced Diabetic Rats. To evaluate of hypoglycemic effects in vivo, we examined blood glucose levels, serum lipid profile and hepatotoxicity of streptozotocin (STZ) induced diabetic rats. Hypoglycemic effect of CM, CM+PSL and CM+PSH groups was significantly higher than DC groups. The activities of ALT, AST and ALP in CM+PSH group were lower than DC, PC groups. These results suggested that processed sulfur with Cordyceps militaris mycelium have activities of hypoglycemic effects.

Purification and Pysiological Characterization of Isoperoxidase from Oat Root Treated with Alachlor (Alachlor 처리후(處理後) 귀리 근단(根端)에 존재(存在)하는 동위과산화효소(同位過酸化酵素) 정제(精製) 및 효소(酵素)의 생리적(生理的) 특성(特性))

  • Kwon, S.W.;Han, K.S.;Kim, J.C.
    • Korean Journal of Weed Science
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    • v.14 no.1
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    • pp.56-61
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    • 1994
  • The cationic isoperoxidases were isolated from oat root tips which had been grown in treatment with $1{\times}10^{-4}$ M alachlor and purified about 30-fold by treatment with ethylalchol and ion exchange chromatography on DEAF-celluose and CM-sephadex medium. The oat root was found to contain three isoperoxidase. The major activity peak (B) represented 65% of the total isoperoxidase activity. After purification, the major peak of isoperoxidase was purified about 37-fold from the oat root. Analysis of the major peroxidase peak(column fraction 58-78) by SDS revealed a single band which corresponed to a molecular mass of 42.5 kD. In vitro, isoperoxidase activies were inhibited by IAA. Isoperoxidase(50 unit) significantly inhibited 70.2% of cell division in oat root and 54.2% of cell elongation in oat coleoptile as compared with control.

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