• Title/Summary/Keyword: single blinded test

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Effects of a Premarital Education Program for Single person (결혼준비교육 프로그램의 적용 효과)

  • Lee, Sung-Hee;Kim, Hee-Sook
    • Women's Health Nursing
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    • v.13 no.4
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    • pp.272-279
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    • 2007
  • Purpose: The purpose was to test the effects of a premarital education program for singles on their sex role attitude and marriage expectations. Method: Forty seven single people were recruited through website advertisements. Volunteers were randomly assigned either to participate in a 4 week premarital education program(2 hours per week)(n=23) or the option to get a hand-out used with the experimental group after a post-test(n=24). An interviewer blinded to the randomization collected questionnaire data from all subjects at pre and post test. The program covered 2 thematic areas: the value of marriage and gender equity-relations. The data was analyzed using $X^2$-test, t-test, and ANCOVA. Result: There was a significant difference in the marriage-expectation score between the two groups. However, the sex role attitudes score in the experimental group was not significantly different from that of the control group. Conclusion: This premarital education program for singles had positive effects on marriage expectations but not on sex role attitude. Longer follow-up might be needed to evaluate these effects.

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Evaluation on Toxicity of Habitual dose of Extract of Rheum Palmatum through Single Blinded Pilot Study (단일맹검시험을 통한 대황(大黃) 상용량(常用量)의 독성작용 평가)

  • Kwon, Hyork;Chi, Gyoo-Yong;Eom, Hyun-Sup
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.3
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    • pp.390-400
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    • 2010
  • This study is aimed to test physiological and hematological actions of Rheum palmatum through clinical pilot study optimized for usual oriental medicine prescription. Thirty-one cases were finally collected and the sample extract 100 $m{\ell}$ of Rheum palmatum (ERP) was administered two times in a day during 3 days and checked with blood CBC test, urinalysis, liver function test, abdominal X-ray as well as general diagnostic process of oriental medicine; pattern identification, assessment of shapes and constitution. The total toxic effective rate of ERP was 9.68% in 3 cases of the whole in case of consistent uneasy state in the subjective symptomatic assessment and aggravation of blood and urine examination. The relevant diagnostic factors were so-eum constitution and essence type subject, carapaces species, lung type in the aspect of Jisan shape theory. On the other hand, the positive effective rate of ERP was 29.03% manifesting improvement of vital signs or present illness and no abnormal changes of blood chemistry and urinalysis and simple abdomen radiology. The relevant diagnostic factors were tae-eum constitution, energy type subject, aves species, heart and liver type in Jisan's shape theory. And the other cases were manifesting no specific change through the administration of ERP. The ratio of the numbers of decrease and increase was 44:5 in the tenderness and hardness of abdominal palpation. But if the pattern identification doesn't comply with the aim of rhubarb application despite of constipation and abdominal pain, the tendeness and biochemical report was shown in abnormal change. The mean number of diarrhea by ERP was $16.77{\pm}6.95$ during 3 days after administration, and the frequent areas of abdominal pain were lower>middle>upper in order, and it meant the target site of ERP too. Besides, the toxic reaction against ERP was expressed highly in case of decrease in blood cell count and hemoglobin, hematocrit having blood deficiency syndrome. Likewise, the toxicity of ERP was influenced by pattern identification manifesting present disease condition and diagnostic factors of four constitutions, Jisan's shape theory collaterally. In conclusion, evaluation of herbal toxicity in order for using as a clinical guideline, various diagnostic pattern information and shape features like the above should be studied together with other pharmacologic toxicology test for the future.

The effect of single trial transcutaneous electrical nerve stimulation on balance and gait function in elderly people with dementia: a pilot study

  • Jung, Ju Yeon;Jung, Jin-Hwa;Hahm, Suk-Chan;Jung, Kyoungsim;Kim, Sung-Jin;Suh, Hye Rim;Cho, Hwi-young
    • Physical Therapy Rehabilitation Science
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    • v.6 no.2
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    • pp.59-64
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    • 2017
  • Objective: Elderly people with dementia experience not only cognitive dysfunction but also motor function deficits, such as balance and gait impairments. Recently, transcutaneous electrical nerve stimulation (TENS) has been used to reduce pain as well as to control muscle spasm, spasticity and motor performance in various types of subjects. The purpose of this study determined the effect of a single trial TENS on balance and gait function in elderly people with dementia. Design: A randomized controlled trial. Methods: Twenty-two subjects with dementia were assigned to the TENS group (n=12) and ten subjects were assigned to the control group (n=10) randomly. Subjects were classified into two groups: the TENS group (n=12) and the placebo-TENS group (n=10). The TENS group had electrical stimulation applied on the calf muscle for 15 minutes, while the placebo-TENS group had not received real electrical stimulation. The timed up and go test (TUG) and functional reach test (FRT) were used to measure the balance function, and the 10 meters walk test (MWT) and 6MWT were used to assess gait ability. All tests were performed before and after intervention under a single-blinded condition. Results: After intervention, there were significant improvements in TUG, FRT, 10MWT, and 6MWT results in the TENS group (p<0.05), while the placebo-TENS group did not show significant changes in all outcome measurements. There were also differences in all tests between the two groups at post-measurements (p<0.05). Conclusions: This study demonstrated that a single trial TENS application on the calf may be used to improve balance and gait function in elderly people with dementia.

Effects of Backward Walking Training with Task Orientation on the Functional Gait of Children with Spastic Hemiplegia

  • Choi, Ji Young;Son, Sung Min;Kim, Chang Ju
    • The Journal of Korean Physical Therapy
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    • v.31 no.5
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    • pp.292-297
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    • 2019
  • Purpose: This study examined the effects of backward walking training with task orientation on the functional walking ability of children with cerebral palsy. Methods: This study was a single-blinded, randomized controlled trial with a crossover design conducted at a single rehabilitation facility with cross-over to the other intervention arm following a two-week break. For a total of 12 children with spastic hemiplegia cerebral palsy, the forward walking training group (n=6) underwent training three times a week for three weeks, 40 minutes a day, and the backward walking training group (n=6) was also trained under the same conditions. To identify the functional walking ability, variables, such as the walking speed, stride length, and step length, were measured using a walk analyzer (OptoGait, Microgate S.r.l, Italy). Results: Both groups showed significant increases in walking speed, stride length, and step length (p<0.01). The backward walking group showed more significant improvement in the walking speed from pre- to post-test (p<0.05). The gait characteristics were similar in the two groups (stride length and step length) but the walking speed in the backward walking group showed a mean difference between the positive effects higher than the forward walking group. Conclusion: Task-oriented backward walking training, which was conducted on the ground, may be a more effective treatment approach for improving the walking functions of spastic hemiplegia children than forward walk training.

Study on the Efficacy of Acupuncture with Real and Sham Needle on Healthy Subjects: Single-Blind Test using Electrogastrogram (건강인을 대상으로 거짓침과 진짜 침을 이용한 침의 효능에 대한 연구: 위전도를 이용한 단일맹검)

  • Jang, Keuk Young;Kim, Kun Yil;Yu, Jun Sang;Kho, Chan Hee;Lee, Hyun Sook
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.28 no.1
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    • pp.107-112
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    • 2014
  • This study aimed to prove the effects of acupuncture treatment on acupoint Joksamni(ST36) related to gastrointestinal movement. Electrogastrogram (EGG) data were obtained in 11 healthy subjects treated by real or sham needle in single-blinded condition for 40 min, including before, during acupuncture treatment, and after removing needle. According to frequency analysis of EGG, median frequency(MF) was increased by real needle in 4 subjects, MF for another 2 subjects were increased by real and sham needle and no trend shift in MF showed in other 5 subjects. Our result showed that acupuncture treatment on Joksamni has some effects on gastrointestinal movement. In this study we have applied both real acupuncture and sham acupuncture on the same subjects. So its blinding was regarded as good but was effective in about 36%~55%. Two subjects were assumed that they showed placebo effects on both real and sham acupuncture. Therefore it is necessary to perform further study on case-control and a larger number of subjects with functional dyspepsia, in order to confirm our findings.

The Effects of Whole Body Vibration on Knee Extensor Strength, and Balance and Walking Ability with Chronic Stroke (전신 진동 운동이 만성 뇌졸중 환자의 슬관절신전근력, 균형 및 보행능력에 미치는 영향)

  • In, Tae-Sung;Song, Chang-Ho
    • Journal of the Korean Society of Physical Medicine
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    • v.5 no.4
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    • pp.675-683
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    • 2010
  • Purpose : The purpose of this study was to evaluate the effect of Whole body vibration exercise(WBVE) in patient with chronic stroke. Methods : Thirty patients were divided into two groups by randomly experimental group(14 subject) and control group(16 subject) in a single blinded, randomised study. experimental group was conducted for the 6-weeks WBVE program and had a structured exercise program for 16 minutes, 5 days per week and control group was conducted for the shame exercise program. Outcome variables included the knee extensor strength, Berg balance scale, Timed up and go test at 0 and 6 weeks. Results : The experimental group tended to improve more than the control group in balance(Berg balance scale) and walking ability(Timed up and go test). There were no trends in differences in change scores by the knee extensor strength. Conclusion : WBVE program may be helpful to improve knee extensor strengthening, dynamic balance and walking ability for patients with chronic patients.

The Effects of Action Observation Combined with Modified Constraint-induced Movement Therapy on Upper-extremity Function of Subacute Stroke Patients with Moderate Impairment -A Single-blinded Randomized Controlled Trial-

  • Bang, Dae-Hyouk;Lee, Soon-Hyun
    • PNF and Movement
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    • v.18 no.1
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    • pp.23-34
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    • 2020
  • Purpose: To explore the effects of action observation combined with modified constraint-induced movement therapy on upper-extremity function and the activities of daily living in subacute stroke patients. Methods: Twenty-four subacute stroke patients were randomly assigned to the experimental group or the control group (n = 12 each). Both groups received therapy based on motor learning concepts, including repetitive and task-specific practice. The experimental group watched video clips for 10 minutes related to tasks performed during modified constraint-induced movement therapy while the control group watched videos unrelated to upper-extremity movement. These programs were performed for 40 minutes a day five times a week for four weeks. Their scores on the Fugl-Meyer assessment of upper extremities (FMA-UE), the action research arm test (ARAT), a motor activity log (amount of use [AOU] and quality of movement [QOM]), and the modified Barthel index (MBI) were recorded. Results: In both groups, all variables were significantly different between the pre-test and post-test periods (p < 0.05). The post-test variables were significantly different within each group (p < 0.05). In the experimental group, the changes between pre-test and post-test scores in the FMA-UE (14.39 ± 4.31 versus 6.31 ± 4.63), the ARAT (16.00 ± 4.73 versus 11.46 ± 3.73), MAL-AOU (1.57 ± 0.15 versus 1.18 ± 0.28), and MBI (27.54 ± 4.65 versus 18.08 ± 8.52) were significantly higher than those of the control group (p < 0.05). Conclusion: These findings suggest that action observation combined with modified constraint-induced movement therapy may be a beneficial rehabilitation option to improve upper-extremity function in subacute stroke patients with moderate impairment.

Changes in Sensory Function After Transcranial Direct Current Stimulation on Primary Motor Cortex Area

  • Min, Dong-Ki
    • Physical Therapy Korea
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    • v.21 no.4
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    • pp.1-8
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    • 2014
  • Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low-intensity direct current to cortical areas, thereby facilitating or inhibiting spontaneous neuronal activity. This study was designed to investigate changes in various sensory functions after tDCS. We conducted a single-center, single-blinded, randomized trial to determine the effect of a single session of tDCS with the current perception threshold (CPT) in 50 healthy volunteers. Nerve conduction studies were performed in relation to the median sensory and motor nerves on the dominant hand to discriminate peripheral nerve lesions. The subjects received anodal tDCS with 1 mA for 15 minutes under two different conditions, with 25 subjects in each groups: the conditions were as follows tDCS on the primary motor cortex (M1) and sham tDCS on M1. We recorded the parameters of the CPT a with Neurometer$^{(R)}$ at frequencies of 2000, 250, and 5 Hz in the dominant index finger to assess the tactile sense, fast pain and slow pain, respectively. In the test to measure CPT values of the M1 in the tDCS group, the values of the distal part of the distal interphalangeal joint of the second finger statistically increased in all of 2000 Hz (p=.000), 250 Hz (p=.002), and 5 Hz (p=.008). However, the values of the sham tDCS group decreased in all of 2000 Hz (p=.285), 250 Hz (p=.552), and 5 Hz (p=.062), and were not statistically significant. These results show that M1 anodal tDCS can modulate sensory perception and pain thresholds in healthy adult volunteers. The study suggests that tDCS may be a useful strategy for treating central neurogenic pain in rehabilitation medicine.

Effects of Self-Traction Exercises on the Vertebral Alignment, Muscle Strength, and Flexibility of Adults in Their Twenties with Scoliosis

  • Kim, Yongmin;Jeon, Changkeun;Yoo, Kyoungtae
    • Journal of International Academy of Physical Therapy Research
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    • v.10 no.2
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    • pp.1810-1817
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    • 2019
  • Background: Effect of cervical and lumbar tractions on the reduction in the angle of curvature and the effect of a correction exercise or a general traction method on balance, muscle strength, pain, and body alignment, however insufficient research has been undertaken on self traction exercises targeting patients with scoliosis. Purpose: To determine the effect of cervical and lumbar tractions on the reduction in the angle of curvature and the effect of a correction exercise or a general traction method on balance, muscle strength, pain, and body alignment. Design: Randomized controlled clinical trial (single blinded) Methods: Twelve adults(20s) with scoliosis were included in this study and performed a traction program that was composed of a 5-min warm-up exercise, a 15-min main exercise, and a 5-min cool-down exercise (25 minutes in total), three times a week for four weeks. The Chiro traction machine was used for the self-traction exercise. Vertebral alignment, muscle strength, and flexibility were compared before and after the intervention using the paired T-test. Results: The scoliosis angle, pelvic torsion, and lumbar extensor were significantly changed by intervention; however, there was no significant difference in flexibility. Conclusion: The results revealed that self-traction exercise activated blood flow through the extension and contraction of muscles, effectively increasing the function of the muscles around the vertebrae.

Effects of Music-based Sling Exercise Program on Cognition, Walking, and Functional Mobility in Elderly with Dementia: Single-blinded, Randomized Controlled Trial (음악 기반 슬링운동 프로그램이 치매환자의 인지, 보행 및 기능적 운동성에 미치는 효과)

  • Park, Hyun-Ju;Kang, Tae-Woo;Oh, Duck-Won
    • Journal of the Korean Society of Physical Medicine
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    • v.14 no.4
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    • pp.143-152
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    • 2019
  • PURPOSE: This examined the effects of a sling exercise based on music on the cognition, physical performance of patients with dementia. METHODS: Thirty subjects with dementia volunteered to participate in this study. All subjects were allocated randomly to either the experimental group or control group, with 15 subjects in each group. All subjects underwent the exercise program for an average of 60 minutes per day for 16 weeks. The experimental group performed sling exercise based on music, and the control group performed the general exercise program. Assessments were made using the Korean version of mini-mental state examination (MMSE-K), 10 m walk test (10MWT), Tinetti mobility test (TMT), and Katz's Index of Independence in activity daily living (KIIADL) to detect changes in the cognitive level and physical performance before and after the 16-week training period. A paired t-test was conducted to compare the within-group change before and after the intervention. An independent t-test was performed to compare the between-group difference. The statistical significance level was set to α=.05 for all variables. RESULTS: The experimental group showed significant within-group changes in the MMSE-K, 10MWT, TMT, and KIIADL (p<.05). The control group showed a significant change in only the KIIADL (p<.05). A significant difference was observed between the experimental group and the control group regarding the change in MMSE-K and KIIADL after the interventions (p<.05). CONCLUSION: A music-based sling exercise program effectively improves cognition, physical performance, and ADL in patients with dementia. Further studies with a wider range of subjects and scientific equipment will be needed to strengthen the results of this study.