인삼(人蔘) Alkaloidal Fraction이 지질대사(脂質代謝)에 미치는 영향(影響)

Effects of Ginseng Alkaloidal Fraction on Lipid Metabolism

  • 권영소 (서울대학교 의과대학 약리학교실) ;
  • 오진섭 (서울대학교 의과대학 약리학교실)
  • Kwon, Yong-So (Department of Pharmacology, College of Medicine, Seoul National University) ;
  • Oh, Jin-Sup (Department of Pharmacology, College of Medicine, Seoul National University)
  • 발행 : 1969.06.30

초록

Alkaloidal fraction, a principle of ginseng extract was administered to rats orally in the amount of 2.5 mg per day per 100 gm body weight continuously for eight weeks to assess the lipid content of the serum and liver tissue. The findings can be summarized as follows: 1. Total cholesterol contents of serum and liver tissue were found to decrease with the administration of ginseng alkaloidal fraction. 2. Phospholipid contents increased in the serum and decreased in the liver tissue with the administration of ginseng alkaloidal fraction. 3. Triglyceride contents of the serum as well as liver tissue increased with the administration of ginseng alkaloidal fraction during the first 4 weeks but decreased in the second 4 weeks to reach a level below that of the pre-experimental period.

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