The Korean Journal of Pharmacology (대한약리학회지)
- Volume 5 Issue 1
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- Pages.39-43
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- 1969
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- 0377-9459(pISSN)
Anti-inflammatory Action of Glycyrrhetic Acid Derivatives
Glycyrrhetic acid 유도체(誘導體)의 소염작용(消炎作用)
- Kyung, Woo-Hyun (Department of Pharmacology, College of Medicine Seoul National University)
- 경우현 (서울대학교 의과대학 약리학교실)
- Published : 1969.06.30
Abstract
In the present investigation, the anti-inflammatory activity of glycyrrhetic acid derivatives (abbreviated as AMKOA, 28-OMKOA, 30-OMKOA) was compared with hydrocortisone and sodium salicylate by a new anti-inflammatory test, utilizing the chorio-allantoic membrane of the chick embryo, which is outstandingly suitable for large scale screening of new compounds. The anti-inflammatory activity of the glycyrrhetic acid derivatives was similar to hydrocortisone and superior to sodium salicylate.
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