창이자로부터 항산화 유효 성분의 분리

Isolation of Antioxidants from the Seeds of Xanthium strumarium

  • 이윤미 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 강대길 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 김명규 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 최덕호 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 이호섭 (원광대학교 한의학전문대학원 한약자원개발학과)
  • Lee Yun Mi (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Kang Dae Gill (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Kim Myung Gyu (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Choi Deok Ho (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University) ;
  • Lee Ho-Sub (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang University)
  • 발행 : 2004.06.01

초록

In the courses of in vitro screening for the antioxidant effect of the various extracts from medicinal plants, n-BuOH soluble extract of the seeds of Xanthium strumarium was found to exhibit distinctive antioxidant activity. Further purifications of this extract as guided by in vitro antioxidant assay afforded caffeic acid and 3,5-di-O-caffeoyl quinic acid, which scavenged 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical in a dose-dependent manner of which IC50 values were 23.4 μg/ml (132.9 μM) and 29.8 μg/ml (57.9 μM), respectively.

키워드

참고문헌

  1. 천연물 화학 연구법 우원식
  2. 한국식품영양과학회지 v.26 no.1 rkfrmsdptj 분리한 daidzin 및 puerarin의 사람 low density lipoprotein에 대한 항산화 효과 박종옥;김경순;지영애;류병호
  3. 약초의 성분과 이용 최옥자;과학백과사전 출판사(엮음)
  4. 단국대학교 석사학위논문 농산부산물에서 항산화 활성 물질의 검색 김삼인
  5. 천연물 과학 강삼식;윤혜숙;장일무
  6. Food Technol v.73 Antioxidants; Tools for preventing Lipid Oxidation. James Giese
  7. Sci Food Agric The phenolic constituents of Prunus domestica Swain T;Hillis WE
  8. Cereal Chem v.70 no.6 A group of phenolic antioxidants in oats. Dimberg LH;Theander O
  9. Nutr Rev v.53 no.3 The role of phenolics, conjugated linoleic acid, carnosine, and pyrroloquinoline quinineas nonessential dietary antioxidants. Decker EA
  10. Food Biotechnol v.2 no.1 Food Antioxidants. Hahm TS;King DL;Min DB
  11. 한국식품과학회지 v.24 no.6 음약곽 추출물 중의 항산화 성분의 분리 및 성질 김성렬;김진환;김승겸
  12. Kor J Food & Nutr v.16 no.1 Identification of antioxidative component from stem bark of Rhus verniciflua Kim JB
  13. 한국식품과학회지 v.35 no.3 복분자 열매에서 항산화 활성을 지닌 quercetin의 분리 및 동정 윤인;위지향;문제학;안태희;박근형
  14. 한국본초(1)도감 안덕균
  15. 한국의 약용식물 배기환
  16. J Ethnopharmacology v.87 no.2-3 Screening and comparison of antioxidant activity of solvent extracts of herbal medicines used in Korea. Kang DG;Yun C;Lee HS
  17. Phytochemisty. v.46 no.6 Thiazinedione from Xanthium Strumarium. Ma YT;Huang MC;Hsu FL;Chang HF
  18. J Ethnopharmo-cology v.83 Angiotensin converting enzyme inhibitors from cuscuta japonica. Oh H;Kang DG;Lee SY;Lee HS
  19. Drugs v.42 Drug antioxidant effects Halliwell B
  20. J Act Oxyg Free Rad v.1 Antioxidants Fukuzawa K;Takaishi Y
  21. Free radicals in biology v.6 Pryored WA
  22. Colorants Food Colorants Von JH;Elbe SJ
  23. Royal Soc Chemistry Natural antioxidants & food quality in atherosclerosis and cancer prevention, in role of oxidative stress in atherosclerosis and cancers Salonen TT;Herttaala Y.