Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Effect of Sabaek-san on the Immunomodulatory Action

사백산의 면역조절 효과

  • Cho Seoung Yeoun (Department of Pathology, College of Oriental Medicine, Woosuk University) ;
  • Lee Dong Joe (Department of Pathology, College of Oriental Medicine, Woosuk University) ;
  • Jeong Han Sol (Department of Pathology, College of Oriental Medicine, Woosuk University) ;
  • Lee Sang Ryong (Department of AM-Pointology, College of Oriental Medicine, Woosuk University) ;
  • Lee Kwang Gyu (Department of Pathology, College of Oriental Medicine, Woosuk University)
  • 조성연 (우석대학교 한의과대학 병리학교실) ;
  • 이동주 (우석대학교 한의과대학 병리학교실) ;
  • 정한솔 (우석대학교 한의과대학 병리학교실) ;
  • 이상룡 (우석대학교 한의과대학 경혈학교실) ;
  • 이광규 (우석대학교 한의과대학 병리학교실)
  • Published : 2004.02.01
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Abstract

The purpose of this research was to investigate the effect of Sabaek-San(SBS) on the activity of immune cell and leukemia cell. The addition of SBS(1 ㎍/㎖) enhanced the proliferation of cultured-splenocytes and thymocytes. And also, administration of SBS(250, 500 mg/kg) accelerated subpopulation of splenic T lymphocytes in BALB/c mice. Administration of SBS eminently enhanced the production of IFN-γ, and IL-4. The treatment of high dose of SBS inhibit the proliferation of Jurkat cells and dose-dependently increased the apoptosis of cultured-Jurkat leukemia cells. These results suggest that SBS have a cell mediated immuno-regulatory effect.

Keywords

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