Annals of Clinical Neurophysiology

The Korean Society of Clinical Neurophysiology (대한임상신경생리학회)
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Colchicine Induced Myopathy Presenting Electrophysiologic Myotonia

근전도상 근긴장증이 관찰되는 콜치신에 의한 근병증 1예

  • Yang, Ji-Won (Department of Neurology, Gachon University of Medicine, Gil Medical Center) ;
  • Kim, Na-Re (Department of Pathology, Gachon University of Medicine, Gil Medical Center) ;
  • Park, Kee-Hyung (Department of Neurology, Gachon University of Medicine, Gil Medical Center)
  • 양지원 (가천의과학대학교 길병원 신경과) ;
  • 김나래 (가천의과학대학교 길병원 병리과) ;
  • 박기형 (가천의과학대학교 길병원 신경과)
  • Received : 2009.03.18
  • Accepted : 2009.08.21
  • Published : 2009.12.30
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Abstract

Colchicine is widely used in the treatment of gouty arthritis, and chronic use of colchicine can cause vacuolar myopathy. We report colchicine-induced myopathy with electrophysiological myotonia in a patient with gouty arthritis. A 86-year-old man with gouty arthritis presented with progressive proximal weakness and gait disturbance. Electrophysiological finding showed myotonic myopathy and muscle biopsy revealed a vacuolar myopathy. His symptoms soon resolved with the discontinuation of colchicine.

Keywords

References

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