Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Antimicrobial Effect of Scutellariae Radix and Its Thermal Stability

황금 추출물의 항균효과 및 열안정성

  • Kim, Jong-Myoung (Department of Marine Biomaterials & Aquaculture, PuKyong National University) ;
  • Lee, Chul-Won (Institute of Marine BioTechnology, Pusan National University) ;
  • Ahn, Yong-Tae (Institute of Marine BioTechnology, Pusan National University) ;
  • Lee, Ho (Beautiful Science & Technology Inc. Ltd.) ;
  • Kim, Chul (Beautiful Science & Technology Inc. Ltd.) ;
  • Kim, Hyung-Woo (School of Korean Medicine, Pusan National University) ;
  • Cho, Su-In (School of Korean Medicine, Pusan National University) ;
  • An, Won-Gun (Institute of Marine BioTechnology, Pusan National University)
  • 김종명 (부경대학교 해양바이오신소재학과) ;
  • 이철원 (부산대학교 해양생물기술연구소) ;
  • 안용태 (부산대학교 해양생물기술연구소) ;
  • 이호 ((주)바이오 스킨테크) ;
  • 김철 ((주)바이오 스킨테크) ;
  • 김형우 (부산대학교 한의학전문대학원) ;
  • 조수인 (부산대학교 한의학전문대학원) ;
  • 안원근 (부산대학교 해양생물기술연구소)
  • Received : 2012.04.23
  • Accepted : 2012.06.04
  • Published : 2012.06.25
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Abstract

The present study investigated the antimicrobial properties of medicinal herbs including Scutellariae Radix (SR: dried root of Scutellariae bicalensis Georgi). Among hot-water extracts of medicinal herbs tested in this study, SR extract showed the most potent antimicrobial activity with minimum inhibitory concentration (MIC) of 0.625 mg/mL. In particular, synergistic effects of antimicrobial activity were observed upon combined application of SR and chitooligosaccharide as indicated by MIC of 0.125 mg/mL and FIC (fractional inhibitory concentration) index of 0.45. Thermal stability analysis indicated that the components responsible for antimicrobial activity was stable for 8 months at $45^{\circ}C$. Antimicrobial activity was proven to be effective in foods as well as in cosmetics as comparable to that of the chemical preservatives.

Keywords

References

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