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The effect of Acacia nilotica bark extract on growth performance, carcass characteristics, immune response, and intestinal morphology in broilers as an alternative to antibiotic growth promoter

  • Muhammad Umer Zahid (Department of Animal Nutrition, University of Veterinary and Animal Science) ;
  • Anjum Khalique (Department of Animal Nutrition, University of Veterinary and Animal Science) ;
  • Shafqat Nawaz Qaisrani (Department of Animal Nutrition, University of Veterinary and Animal Science) ;
  • Muhammad Ashraf (Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences) ;
  • Ali Ahmad Sheikh (Institute of Microbiology, University of Veterinary and Animal Sciences) ;
  • Muhammad Umar Yaqoob (College of Animal Science, Zhejiang University)
  • 투고 : 2022.07.25
  • 심사 : 2023.01.06
  • 발행 : 2023.07.01

초록

Objective: Present study was designed to evaluate the efficacy of Acacia nilotica bark extract as an alternative to antibiotic growth promoters in broilers. Methods: Six hundred, day-old broiler chicks were randomly divided into six groups (NC, without any supplementation; AB, NC+Zinc Bacitracin; PB, NC+Safmannan; ANBE1, NC+A. nilotica bark extract 0.1%; ANBE3, NC+A. nilotica bark extract 0.3%; ANBE5, NC+A. nilotica bark extract 0.5%), with ten replicates per group (10 chicks/replicate) and feeding trial was lasted for 35 days. Results: Results showed that weight gain (1,296.63 g) and feed conversion ratio (FCR, 1.59) of AB was better than NC, during the finisher phase. Overall FCR of AB (1.53), PB (1.54), and ANBE5 (1.54) was significantly (p<0.05) better than NC. From carcass parameters relative weight of wing and heart were highest in ANBE3 (2.5% and 1.51%, respectively). Significantly (p<0.05) highest blood glucose level was observed in NC (264.5 mg/dL) and highest albumin concentration was found in AB (1.46 mg/dL). In addition, antibody titer levels against ND and IBD were higher in ANBE5 than NC, while higher relative weight of bursa was observed in ANBE3 than NC. The villus height to crypt depth ratio in all experimental groups was better than NC. Conclusion: Acacia nilotica bark extract could be a suitable alternative to antibiotic growth promoters to support the growth in broilers.

키워드

과제정보

The authors acknowledged the Sultan Feed Pvt. Ltd., Sargodha, Pakistan for providing necessary facilities to conduct feeding trial.

참고문헌

  1. Yaqoob MU, Wang G, Wang M. An updated review on probiotics as an alternative of antibiotics in poultry. Anim Biosci 2022;35:1109-20. https://doi.org/10.5713/ab.21.0485
  2. Sorum H, Sunde M. Resistance to antibiotics in the normal flora of animals. Vet Res 2001;32:227-41. https://doi.org/10.1051/vetres:2001121
  3. Mathew AG, Cissell R, Liamthong S. Antibiotic resistance in bacteria associated with food animals: a United States perspective of livestock production. Foodborne Path Dis 2007;4:115-33. https://doi.org/10.1089/fpd.2006.0066 
  4. Akbar A, Anal AK. Isolation of Salmonella from ready-toeat poultry meat and evaluation of its survival at low temperature, microwaving and simulated gastric fluids. J Food Sci Technol 2015;52:3051-7. https://doi.org/10.1007/s13197-014-1354-2 
  5. Castanon JIR. History of the use of antibiotic as growth promoters in European poultry feeds. Poult Sci 2007;86:2466-71. https://doi.org/10.3382/ps.2007-00249
  6. Diarra MS, Malouin F. Antibiotics in Canadian poultry productions and anticipated alternatives. Front Microbiol 2014; 5:282. https://doi.org/10.3389/fmicb.2014.00282
  7. Marshall BM, Levy SB. Food animals and antimicrobials: impacts on human health. Clin Microbiol Rev 2011;24:718-33. https://doi.org/10.1128/CMR.00002-11
  8. Braga LC, Leite AAM, Xavier KGS, et al. Synergic interaction between pomegranate extract and antibiotics against Staphylococcus aureus. Can J Microbiol 2005;51:541-7. https://doi.org/10.1139/w05-022
  9. Mitcher LA, Okwute SK, Gollapudie SR, Drake S, Anova E. Antimicrobial pterocarpans of nigerian Erythrina mildbraedii. Phytochemistry 1988;27:3449-52. https://doi.org/10.1016/ 0031-9422(88)80746-5 
  10. Akinmoladun AC, Ibukun EO, Afor E, et al. Chemical constituents and antioxidant activity of Alstonia boonei. Afr J Biotechnol 2007;6:1197-201. 
  11. Surai PF. Selenium in poultry nutrition. Reproduction, egg and meat quality and practical applications. World's Poult Sci J 2002;58:431-50. https://doi.org/10.1079/WPS20020032 
  12. Ngambi JW, Nakalebe PM, Norris D, Malatje MS, Mbajiorgu CA. Effects of dietary energy level and tanniferous Acacia karroo leaf meal level of supplementation at finisher stage on performance and carcass characteristics of Ross 308 broiler chickens in South Africa. Int J Poult Sci 2009;8:40-6.  https://doi.org/10.3923/ijps.2009.40.46
  13. Lee K, Kim J, Oh S, Kang C, An B. Effects of dietary sanguinarine on growth performance, relative organ weight, cecal microflora, serum cholesterol level and meat quality in broiler chickens. J Poult Sci 2015;52:15-22. https://doi.org/10.2141/jpsa.0140073 
  14. Kim S, Lee K, Kang C, An B. Growth performance, relative meat and organ weights, cecal microflora, and blood characteristics in broiler chickens fed diets containing different nutrient density with or without essential oils. Asian-Australas J Anim Sci 2016;29:549-54. https://doi.org/10.5713/ajas.15.0426 
  15. Amad AA, Wendler KR, Zentek J. Effects of a phytogenic feed additive on growth performance selected blood criteria and jejunal morphology in broiler chickens. Emir J Food Agric 2013;25:549-54. https://doi.org/10.9755/ejfa.v25i7.12364 
  16. Odebiyi OO, Sofowora EA. Phytochemical screening of Nigerian medicinal plants II. Lloydia 1978;41:234-46. 
  17. Gundidza M. Phytochemical screening of some Zimbabwean medicinal plants. Cent Afr J Med 1985;31:238-9. https://doi.org/10.10520/AJA00089176_1836 
  18. Ebana RUB, Madunagu BG, Etok CA. Antimicrobial effect of Strophanthus Lipidis and Seramone afzelii on some pathogen bacterial and their drug resistant strains. Nig J Bot 1993;6:27-31. 
  19. Kumar B, Kumbhakar NK. Haematobiochemical profile of Aseel in Chhattisgarh region. Indian Vet J 2015;92:40-2. 
  20. Xie D, Wang ZX, Dong YL, et al. Effects of monochromatic light on immune response of broilers. Poult Sci 2008;87:1535-9. https://doi.org/10.3382/ps.2007-00317 
  21. Saini ML, Saini R, Roy S, Kumar A. Comparative pharmacognostical and antimicrobial studies of acacia species (Mimosaceae). J Med Plant Res 2008;2:378-86. https://doi.org/10.5897/JMPR.9000378 
  22. Abudabos AM, Abdullah HA, Yousif MD, Khan RU. The effect of phytogenic feed additives to substitute in-feed antibiotics on growth traits and blood biochemical parameters in broiler chicks challenged with Salmonella typhimurium. Environ Sci Pollut Res 2016;23:24151-7. https:// doi.org/10.1007/s11356-016-7665-2 
  23. Festus N, Bright SG, Orile JE, Anita F. Effect of oral administration of aqueous extract of Moringa oleifera seeds, gum arabic and wild mushroom on growth performance of broiler chickens. Inter J Med Plant Res 2016;5:200-8. 
  24. Marimuthu S, D'Souza P. Field performance of Kolin Plus, a poly herbal formulation to replace synthetic choline chloride. Int J Vet Sci Anim Husb 2019;4:32-4. 
  25. Olorede BR, Alade AR, Ajagbonna OP. Effects of substituting groundnut cake with acacia seed kernel meal on performance, haematology, serum biochemical parameters and economy of production of broilers. Trop J Anim Sci 2000;3:107-15.  https://doi.org/10.4314/tjas.v3i2.49783
  26. El-Galil A, Hassan MM, Abu El-Soud KM, El-Dayem A, Salem FM. Utilization of acacia saligna leaf meal as a nontraditional feedstuff by local growing hens under desert conditions. Egypt J Nutr Feeds 2019;22:211-7.  https://doi.org/10.21608/ejnf.2019.76354
  27. Buchanan NP, Hott JM, Cutlip SE, Rack AL, Asamer A, Moritz JS. The effects of a natural antibiotic alternative and a natural growth promoter feed additive on broiler performance and carcass quality. J Appl Poult Res 2008;17:202-10. https://doi.org/10.3382/japr.2007-00038 
  28. Khan RU, Naz S, Nikousefat Z, Tufarelli V, Laudadio V. Thymus vlugaris: alternative to antibiotics in poultry feed. World's Poult Sci J 2012;68:401-8. https://doi.org/10.1017/S0043933912000517 
  29. Natarajan M, Srinivasan M. Antidiabetic and antioxidant activity of Acacia nilotica leaf on alloxan induced diabetic rats. Int J Pharm Biol Sci 2015;6:110-26. 
  30. Mukundi MJ, Piero NM, Mwaniki NE, et al. Antidiabetic effects of aqueous leaf extracts of acacia nilotica in alloxan induced diabetic mice. J Diabetes Metab 2015;6:1000568. https://doi.org/10.4172/2155-6156.1000568 
  31. Abuelgassim AO. Antioxidant potential of date palm leaves and Acacia nilotica fruit in comparison with other four common Arabian medicinal plants. Life Sci J 2013;10:3405-10. 
  32. Umaru B, Saka S, Mahre MB, Dogo HM, Ojo NA, Onyiyili PA. Effects of aqueous pod extract of Acacia nilotica on white blood cells, platelets and clotting time in albino rats. Am J Pharmacol Pharmacother 2016;3:001-006. https://doi.org/10.21767/2393-8862.100035 
  33. Ladokun O, Ojezele M, Arojojoye O. Comparative study on the effects of aqueous extracts of viscum album (mistletoe) from three host plants on hematological parameters in albino rats. Afr Health Sci 2015;15:606-12. https://doi.org/10.4314/ahs.v15i2.38 
  34. Singh S, Taneja M, Majumdar DK. Biological activities of Ocimum sanctum L. fixed oil-an overview. Indian J Exp Biol 2007;45:403-12. 
  35. Koko WS, Mesaik MA, Yousaf S, Galal M, Choudhary MI. In vitro immunomodulating properties of selected Sudanese medicinal plants. J Ethnopharmacol 2008;118:26-34. https://doi.org/10.1016/j.jep.2008.03.007 
  36. Sharma AK, Amit K, Sharad KY, Rahal A. Studies on antimicrobial and immunomodulatory effects of hot aqueous extract of acacia nilotica L. leaves against common veterinary pathogens. Vet Med Int 2014;2014:747042. https://doi.org/10.1155/2014/747042 
  37. Moghaddam HN, Salari S, Arshami J, Golian A, Maleki M. Evaluation of the nutritional value of sunflower meal and its effect on performance, digestive enzyme activity, organ weight, and histological alterations of the intestinal villi of broiler chickens. J Appl Poult Res 2012;21:293-304. https://doi.org/10.3382/japr.2011-00396 
  38. Salim HM, Kang HK, Akter N, et al. Supplementation of direct-fed microbials as an alternative to antibiotic on growth performance, immune response, cecal microbial population, and ileal morphology of broiler chickens. Poult Sci 2013;92:2084-90. https://doi.org/10.3382/ps.2012-02947 
  39. Vondruskova H, Slamova RB, Trckova M, Zraly ZB, Pavlik I. Alternatives to antibiotic growth promoters in prevention of diarrhoea in weaned piglets: a review. Vet Med 2010;55:199-224. https://doi.org/10.17221/2998-VETMED